$181 Find Cheap Flights from San Diego to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from San Diego to South America departing on 9/5. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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Best South America Flight Deals from San Diego

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours

Lima
Lima1 stop$445
Bogotá
Bogotá1 stop$411
Buenos Aires
Buenos Aires1 stop$743
Rio de Janeiro
Rio de Janeiro1 stop$662
Cartagena
Cartagena1 stop$408
Santiago
Santiago3 stops$906
Quito
Quito1 stop$610
Cali
Cali2 stops$505
Cusco
Cusco2 stops$1,001
Montevideo
Montevideo2 stops$855
Florianopolis
Florianopolis3 stops$914

Cheap Flight Deals from San Diego to South America (SAN-0SA)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from San Diego to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.

Recent round-trip flight deals from San Diego to South America

Recommended round-trip deals departing in the coming months from the most popular airlines that fly from San Diego to South America.
Discover the best prices for you by selecting your travel dates on KAYAK.
Choose your dates
Copa Airlines Logo
9:03 pm - 8:17 amSAN-MDE
9h 14m1 stop
Copa Airlines Logo
9:15 am - 5:50 pmMDE-SAN
10h 35m1 stop
$403Copa Airlines
Find Deal
Fri, Sep 5 - Fri, Sep 12
Copa Airlines Logo
8:58 pm - 8:41 amSAN-CTG
9h 43m1 stop
Copa Airlines Logo
9:22 am - 5:44 pmCTG-SAN
10h 22m1 stop
$408Copa Airlines
Find Deal
Fri, Jul 4 - Wed, Jul 9
United Airlines Logo
6:15 am - 7:20 pmSAN-BOG
11h 05m1 stop
United Airlines Logo
12:14 am - 5:37 pmBOG-SAN
19h 23m1 stop
$513United Airlines
Find Deal
Mon, Jun 2 - Wed, Jun 11
Delta Logo
11:40 am - 10:55 amSAN-BOG
21h 15m2 stops
Delta Logo
10:45 am - 11:45 pmBOG-SAN
15h 00m2 stops
$517Delta
Find Deal
Sun, Sep 7 - Sat, Sep 13
United Airlines Logo
6:43 pm - 8:43 amSAN-CTG
36h 00m2 stops
United Airlines Logo
9:38 am - 12:15 amCTG-SAN
16h 37m2 stops
$518United Airlines
Find Deal
Wed, Jun 4 - Mon, Jun 16
American Airlines Logo
6:15 am - 10:30 pmSAN-BOG
14h 15m1 stop
American Airlines Logo
12:25 am - 8:46 pmBOG-SAN
22h 21m1 stop
$522American Airlines
Find Deal
Sun, May 18 - Thu, May 22
Delta Logo
3:35 pm - 7:15 pmSAN-BOG
25h 40m1 stop
Delta Logo
9:00 am - 9:19 pmBOG-SAN
14h 19m1 stop
$524Delta
Find Deal
Wed, Jun 4 - Fri, Jun 13
LATAM Airlines Logo
10:30 pm - 7:58 pmSAN-BOG
19h 28m2 stops
LATAM Airlines Logo
1:35 am - 11:29 pmBOG-SAN
23h 54m2 stops
$589LATAM Airlines
Find Deal
Tue, Jun 3 - Sun, Jun 15
LATAM Airlines Logo
10:30 pm - 7:58 pmSAN-BOG
19h 28m2 stops
LATAM Airlines Logo
10:45 am - 11:42 pmBOG-SAN
14h 57m2 stops
$596LATAM Airlines
Find Deal
Tue, May 20 - Thu, May 22
American Airlines Logo
11:00 pm - 8:20 pmSAN-LIM
19h 20m1 stop
American Airlines Logo
10:00 pm - 9:53 pmLIM-SAN
25h 53m1 stop
$659American Airlines
Find Deal
Sun, Aug 31 - Mon, Sep 15

KAYAK's insights & trends for San Diego to South America flights

Get data-powered insights and trends into flights from San Diego to South America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest time of day to fly to South America?

The average price for all round-trip flights from San Diego to South America depending on the time of departure, clicked by users on KAYAK in the last 2 weeks.
The cheapest time of day to fly to South America is generally at night, when round-trip flights cost $736 on average. Morning departures are around 8% more expensive than evening flights, on average. The most expensive time of day to fly to South America is generally in the morning, which is peak travel time and where the average cost of a ticket is $808.

What is the cheapest month to fly from San Diego to South America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from San Diego to South America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.
The cheapest month for flights from San Diego to South America is February, when tickets cost $684 (return) on average. On the other hand, the most expensive months are December and June, when the average cost of round-trip tickets is $998 and $981 respectively.

What’s the cheapest day of the week to fly from San Diego to South America?

The average price of all round-trip flights from San Diego to South America clicked on KAYAK for each day over the last 12 months.
Your flight ticket price will generally be cheaper if you fly to South America on a Monday and more expensive on a Friday. On your return trip to San Diego, you should consider flying back on a Tuesday, and avoid Fridays for better deals.

How far in advance should I book a flight from San Diego to South America?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from San Diego to South America, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.
To get a below average price on the flight from San Diego to South America, you should book around 5 weeks before departure. For the absolute cheapest price, our data suggests you should book 25 weeks before departure.

Good to know

Low season

February

High season

December

Cheapest flight

$181
Best time to beat the crowds with an average 12% drop in price.
Most popular time to fly with an average 40% increase in price.
Flight from San Diego to Medellín

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from San Diego to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from San Diego to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from San Diego to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from San Diego to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from San Diego to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from San Diego to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from San Diego to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from San Diego to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Top 5 airlines serving from San Diego to South America

Need help choosing which airline to fly with from San Diego to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
DeltaOverall score based on 7916 reviews
7.9Comfort
7.3Food
8.5Crew
8.2Boarding
7.9Entertainment
Airline reviews

Bathrooms dirty sinks clogged. No one seemed to clean them. Plane very old

4.0 OkayPeter, Mar 2025LAX - SYD
Read more Delta reviews

Bathrooms dirty sinks clogged. No one seemed to clean them. Plane very old

Thank you for not flipping the plane on the run way. You guys get a 5 star rating for the flight!!!

Boarding is, as it always is… horrible. Gate lice. Slow moving zones. Too many people with carry ons

It was terrible, if they ran flights on time it would make a big difference.

Delta seems to be improving in many areas, except they are super bad with the food available. Bring back normal food service on long flights.

I actually received a notification from kayak on email but not one by text from Delta when my departure gait changed and I almost missed my flight

New boarding doesn't make sense. Filling front first is slow.

Delta flight was great from the check in all the way to arrival. However, I had a very bad experience. I requested a wheelchair and the wheelchair employee that went to pick me up from the plane in Boston to bring me to the baggage claims told me I have to pay him. I was under the impression that it was a free service and I usually give tips but the person forced me to pay and since I said no because I was upset with his demand when my daughter walked in to pick me up he demanded payment from my daughter who paid him thinking maybe now it is a charged service.

Horrible. Grateful to be alive but spent 13 hours at airport only to return back to my familys house and flight changed to next day. They tried to fix a part on plane, had no back up plane and after 10 hours , reattempted the flight and it STILL wasn't fixed. We got a meal voucher and rescheduled flight but there should be some other compensation for the 15 hours spent in airport

My seat was changed at the last minute and I was moved to the last row, right next to the bathroom despite selecting my seat well in advance. I was also made to check my carry on due to space but when I got on the plane there was significant empty overhead space. Picking up my carry on from the luggage carousel added time to my trip which had already been extended due to delay.

It would have been better if they don't separate families in seating. We were seated in the aile row in the middle of a family of four. It would have been better if they they seat the family of four together than separated.

I upgraded myself to Business Class at the last minute so I had a DREAMS window seat. Seeing as I've never flown Business before everything was novel and fun for me and it made the 7 hour flight much more enjoyable for sure.

No headphones given for inflight entertainment. I missed my flight from the previous day and the customer service agent tried to extort an additional $100.00 US from me for missing my flight. Really?!

It was reasonably comfortable trip considering its duration (7 hours). Crew was very good and friendly, seats very more comfortable than other planes. Only negative comment would be that the bathroom light did not get its full brightness 🙃

The flight was delayed about 4 hours without any explanation. No wifi or entertainment at all on planes. Had to pay for checked bags I was allowed according to reservations.

It was good, plane is a bit older so seats are somewhat flat

Well the airline was fine. The only thing is I was charged for a checked in luggage. But when I reserved the ticket it showed a check in bag allowed. Who can I get in contact with for reimbursement.? The airline said I had to speak to whoever I booked ticket with.

I loved my experience. Very safe, Very informative and very friendly.

At JFK the Security line was extremely long and few checkpoints open.

Flight attendant -José? - was over the top friendly and professional. Beautiful new plane with lie flat seats in Business (worth it!)

We didn’t have any entertainment. I tried to go online without success. The airplane was extremely cold and they didn’t have blankets.

It was good, however the airplane was really cold. We received snacks and the crew was friendly.

Delta has an outstanding service. They are courteous and punctual most of the time. The flight departed a half hour late but we arrived 15 minutes early.

Not sure why there are so many security checks at this airport. Consistently annoying showing passport over and over, checking carryons at gate all the while trying to make tight connection. Basically it was uncomfortable crowded cabin with meidiocre service

Although the flight is goof and the crew is good, the way the airline charges you for every service is ridiculous.

Plane never left the ground. Mech issues - entire trip was rerouted through united.

Everything was good except the check in. Could not do it online neither on the machines in the airport. Needed special assistance from the airline desk clerk

No entertainment but not expected. Unless you are referring to monitor that you can use. Then Al, was fine on all flights.

Friendly staff, It was the first flight out for our plane, so had to be deiced from the frost. Only delayed a few minutes,

Basic experience, we were delayed causing less time to enjoy our destination and on the way back, we boarded when the flight should have been taking off.

The gate was too far away for the connecting flight

Compared with other carriers business class for an overnight was not worth the extra expense.

Seats were comfortable. It’s was so cold and very uncomfortable. I paid 2000 miles for wifi service that was choppy the whole flight. Would like to be reimbursed for my miles Food was so disappointing. Three cold and terrible meals for $3000 round trip. This needs to be better.

Easy to board. Flight was super crowded though so I didn't sleep well on that cross country red-eye flight. The aisles seem ot have gotten narrower and the seat smaller whn luggage and people are getting bigger so it would be AWESOME to have more space and breathing room in general ;)

Pilot Erika DeLong made us feel safe and at ease in a frankly scary time to be flying. Her warm smile and greeting and excellent command of the aircraft in foggy bumpy weather helped us all to calm our nerves and get us home safely.

Plenty of room for me and the cat in Premium Economy. Seat was comfortable. Boarding was a breeze. The lady at the special check-in desk was great, super helpful and professional.

Smooth flight. As always dinner could have been more generous. Breakfast was great.

AWFUL. I have had the experience of traveling with many airlines across the world, and hands down United Airlines is the worst. Not one flight was on time, and I don’t think I met one crew member or staff member who wasn’t rude.

Old and out of date plane, it seem like every time I fly with united there’s and issue. We were delayed,

We took off an hour late due to arrival airport not having enough gates. That was followed by 1:30 wait to get our bags delivered for the entire flight.

British Airways staff are very polite and willing to help.

The plane was late and then sat on the runway for almost 45 minutes before taking off.

We kept being told that the flight was full and that all overhead compartments were full and therefore had to check in our hand luggage. We were some of the last people to board and noticed that there was still sufficient space in the overhead compartments. We were obliged to check in hand luggage when there was space and so had to wait at luggage retrieval which took a while to then noticed damage to our luggage - not a great experience!

Worst seats I’ve ever had !!! The seats were very narrow and uncomfortable and misaligned with the seats in front of mine leading to bottom of the seat in front of mine pressing on my legs for 15.5 hours !

This was an overnight flight. There was no meal service in first class, just a simple snack basket was offered along with beverages. There should have been some type of continental breakfast prior to arrival in PHL. As an Executive Platinum American Airlines Advantage member, I received no name recognition from the first class flight attendant. When disembarking at PHL, the flight attendants were more interested in their cell phones than saying "thank you" to the passengers as they disembarked.

The flight was quick and to the point. The crew just did their job w/o excessive talking and everything was just perfect.

Awkward carry on process. Forced to check all carry on. No overhead space of worthiness. Left delayed, but made up the time. Crew was amicable.

Amazingly comfy flight - I had upgraded for a reasonable price and it was worth it. The food also was good.

Had to wait on pilot and crew to depart and had to wait to arrive at the gate because they only had 2 crews working. Delays, delays....Planes just keep getting smaller and tighter and they nickle and dime for everything. When will an airline actually wake up and make flying more enjoyable?

I paid for what I got which was cheap, I brought my own entertainment. I knew what to expect, so I could be prepared. If you’re flying economy, check in early like me. I have no problems with my flight, was on time, staff were friendly, and overall good experience.

Everything you need to know for your flight to South America

Information on your arrival and departure airports

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