$210 Find Cheap Flights from San Diego to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from San Diego to South America departing on 3/28. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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Best South America Flight Deals from San Diego

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours

Lima
Lima1 stop$497
Bogotá
Bogotá1 stop$435
Buenos Aires
Buenos Aires1 stop$820
Rio de Janeiro
Rio de Janeiro1 stop$569
Cartagena
Cartagena2 stops$298
Santiago
Santiago1 stop$874
Quito
Quito1 stop$509
Guayaquil
Guayaquil2 stops$562
Cali
Cali1 stop$465
Cusco
Cusco2 stops$821
Montevideo
Montevideo2 stops$1,255
Florianopolis
Florianopolis2 stops$633

Cheap Flight Deals from San Diego to South America (SAN-0SA)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from San Diego to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.

Recent round-trip flight deals from San Diego to South America

Recommended round-trip deals departing in the coming months from the most popular airlines that fly from San Diego to South America.
Discover the best prices and deals for you by selecting your travel dates.
Choose your dates
8:07 pm - 12:07 pmSAN-CTG
14h 00m2 stops
1:12 pm - 7:41 amCTG-SAN
20h 29m2 stops
$298Spirit Airlines
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Tue, Mar 25 - Wed, Apr 2
8:07 pm - 1:00 pmSAN-MDE
14h 53m2 stops
2:14 pm - 7:34 amMDE-SAN
19h 20m2 stops
$424Spirit Airlines
Find Deal
Tue, Apr 8 - Wed, Apr 16
6:15 am - 7:15 pmSAN-BOG
11h 00m1 stop
2:55 pm - 10:07 amBOG-SAN
21h 12m1 stop
$512LATAM Airlines
Find Deal
Wed, Apr 9 - Tue, Apr 15
10:16 am - 9:10 pmSAN-MDE
8h 54m1 stop
12:15 am - 9:17 amMDE-SAN
11h 02m1 stop
$513United Airlines
Find Deal
Wed, May 28 - Tue, Jun 10
9:50 pm - 1:40 pmSAN-BOG
13h 50m1 stop
2:55 pm - 10:07 amBOG-SAN
21h 12m1 stop
$513Delta
Find Deal
Mon, Mar 31 - Mon, Apr 14
10:16 am - 9:10 pmSAN-MDE
8h 54m1 stop
12:15 am - 9:14 pmMDE-SAN
22h 59m2 stops
$517United Airlines
Find Deal
Wed, May 28 - Tue, Jun 10
5:15 pm - 4:15 pmSAN-BOG
21h 00m2 stops
2:55 pm - 10:07 amBOG-SAN
21h 12m1 stop
$517Delta
Find Deal
Wed, Apr 9 - Tue, Apr 15
6:15 pm - 1:40 pmSAN-BOG
17h 25m2 stops
9:00 am - 10:49 pmBOG-SAN
15h 49m2 stops
$535LATAM Airlines
Find Deal
Fri, Apr 25 - Thu, May 1
7:30 pm - 11:20 amSAN-BOG
13h 50m2 stops
6:30 am - 7:20 pmBOG-SAN
14h 50m2 stops
$542American Airlines
Find Deal
Wed, Jul 9 - Wed, Jul 23
7:12 am - 10:30 pmSAN-BOG
13h 18m1 stop
12:25 am - 10:01 amBOG-SAN
11h 36m1 stop
$585American Airlines
Find Deal
Wed, Apr 9 - Mon, Apr 14

Good to know

Low season

February

High season

December

Cheapest flight

$210
Best time to beat the crowds with an average 10% drop in price.
Most popular time to fly with an average 40% increase in price.
Flight from San Diego to Cartagena

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from San Diego to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from San Diego to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from San Diego to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from San Diego to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from San Diego to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from San Diego to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from San Diego to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from San Diego to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Top tips for finding cheap flights to South America

  • Book at least 1 week before departure in order to get a below-average price.
  • High season is considered to be January, November and December. The cheapest month to fly from San Diego is February.
  • Morning departure is around 19% more expensive than an evening flight, on average*.
*Average of the lowest prices shown in KAYAK’s search results for departures within the next 30 days

Top 5 airlines serving from San Diego to South America

Need help choosing which airline to fly with from San Diego to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
DeltaOverall score based on 7973 reviews
8.2Boarding
8.5Crew
8.0Comfort
7.3Food
7.9Entertainment
Airline reviews

Bathrooms dirty sinks clogged. No one seemed to clean them. Plane very old

4.0 OkayPeter, Mar 2025LAX - SYD
Read more Delta reviews

Bathrooms dirty sinks clogged. No one seemed to clean them. Plane very old

Thank you for not flipping the plane on the run way. You guys get a 5 star rating for the flight!!!

Boarding is, as it always is… horrible. Gate lice. Slow moving zones. Too many people with carry ons

It was terrible, if they ran flights on time it would make a big difference.

Delta seems to be improving in many areas, except they are super bad with the food available. Bring back normal food service on long flights.

I actually received a notification from kayak on email but not one by text from Delta when my departure gait changed and I almost missed my flight

New boarding doesn't make sense. Filling front first is slow.

Delta flight was great from the check in all the way to arrival. However, I had a very bad experience. I requested a wheelchair and the wheelchair employee that went to pick me up from the plane in Boston to bring me to the baggage claims told me I have to pay him. I was under the impression that it was a free service and I usually give tips but the person forced me to pay and since I said no because I was upset with his demand when my daughter walked in to pick me up he demanded payment from my daughter who paid him thinking maybe now it is a charged service.

Horrible. Grateful to be alive but spent 13 hours at airport only to return back to my familys house and flight changed to next day. They tried to fix a part on plane, had no back up plane and after 10 hours , reattempted the flight and it STILL wasn't fixed. We got a meal voucher and rescheduled flight but there should be some other compensation for the 15 hours spent in airport

My seat was changed at the last minute and I was moved to the last row, right next to the bathroom despite selecting my seat well in advance. I was also made to check my carry on due to space but when I got on the plane there was significant empty overhead space. Picking up my carry on from the luggage carousel added time to my trip which had already been extended due to delay.

I loved my experience. Very safe, Very informative and very friendly.

At JFK the Security line was extremely long and few checkpoints open.

Flight attendant -José? - was over the top friendly and professional. Beautiful new plane with lie flat seats in Business (worth it!)

Horrible food. No wine or any other alcohol is served on the flight. Water is not served often and they refused when I asked for water in two cups. On the other hand, both going and coming back flights were on time.

Seats are getting smaller and smaller...and as hard as a rock , mediocre entertainment

Very good flight and crew Food was a surprise on a short flight

Biggest issue was that they only had two restrooms in the back of the aircraft. Too many people for only two restrooms. The trash was overflowing and there was paper on the floor too. Long lines in the isle to use it. Food was also a bit meh. They don’t offer snacks with drinks, so you might want to buy a snack to hold you off on a longer trip, since the meals are very small.

It was first time fling in copa airline. In general I am satisfied except bag size. I got a email from copa with 17-10-6 for carry on bag. In airport the check in show 22-14-10 . However that mistake means $100,00 in over cost.

On the trip to Rosario, we raw dogged it for 7 hours. No wifi, no charging outlets, Gilbert girls on every third row monitor with no audio. It was better on the return flight—at least we had screens and earplugs.

Have veg meal going forward . Other than e everything was excellent !!!

Everything was good except the check in. Could not do it online neither on the machines in the airport. Needed special assistance from the airline desk clerk

No entertainment but not expected. Unless you are referring to monitor that you can use. Then Al, was fine on all flights.

Friendly staff, It was the first flight out for our plane, so had to be deiced from the frost. Only delayed a few minutes,

Staff encountered friendly and helpful. Flight delayed 1 hour due to mechanical issue, but made it through Atlanta immkgration and security in plenty of time,

Basic experience, we were delayed causing less time to enjoy our destination and on the way back, we boarded when the flight should have been taking off.

reliable, relatively relaxed, helpful and kind staff and clean airplanes. No need for more.

Very poor ! Latam is really excellent in mistreating its premium passengers and their family. They should go out of business for good.

Only complaint is that the entertainment system wasn’t working on our seats and some others.

Please guy check the food I almost end up to the hospital

Very slow boarding, 1 hour late - uncomfortable chairs and crew barely speaking english even at the airport!

Pilot Erika DeLong made us feel safe and at ease in a frankly scary time to be flying. Her warm smile and greeting and excellent command of the aircraft in foggy bumpy weather helped us all to calm our nerves and get us home safely.

Plenty of room for me and the cat in Premium Economy. Seat was comfortable. Boarding was a breeze. The lady at the special check-in desk was great, super helpful and professional.

Smooth flight. As always dinner could have been more generous. Breakfast was great.

AWFUL. I have had the experience of traveling with many airlines across the world, and hands down United Airlines is the worst. Not one flight was on time, and I don’t think I met one crew member or staff member who wasn’t rude.

Old and out of date plane, it seem like every time I fly with united there’s and issue. We were delayed,

We took off an hour late due to arrival airport not having enough gates. That was followed by 1:30 wait to get our bags delivered for the entire flight.

For an 8.5 hour flight the service on board lacked a bit. Service start was slow, the food was worse than usual and they skipped the snack they were supposed to deliver before landing.

Wish movie and music choices changed more often. Mostly same from a month or two ago when I last flew.

It was good. Just that the seats could not be reclined. The people behind were not ready to let the chairs be reclined

Checkin was painful and slow! Lady didn’t seem to know what was going on and couldn’t explain the delay. Seemed ahe couldnt see the computer scree and we couldn’t hear her talk through her mask.

This was an overnight flight. There was no meal service in first class, just a simple snack basket was offered along with beverages. There should have been some type of continental breakfast prior to arrival in PHL. As an Executive Platinum American Airlines Advantage member, I received no name recognition from the first class flight attendant. When disembarking at PHL, the flight attendants were more interested in their cell phones than saying "thank you" to the passengers as they disembarked.

The flight was quick and to the point. The crew just did their job w/o excessive talking and everything was just perfect.

Awkward carry on process. Forced to check all carry on. No overhead space of worthiness. Left delayed, but made up the time. Crew was amicable.

Amazingly comfy flight - I had upgraded for a reasonable price and it was worth it. The food also was good.

Had to wait on pilot and crew to depart and had to wait to arrive at the gate because they only had 2 crews working. Delays, delays....Planes just keep getting smaller and tighter and they nickle and dime for everything. When will an airline actually wake up and make flying more enjoyable?

I paid for what I got which was cheap, I brought my own entertainment. I knew what to expect, so I could be prepared. If you’re flying economy, check in early like me. I have no problems with my flight, was on time, staff were friendly, and overall good experience.

DO NOT BOOK THROUGH AMERICAN AIRLINES IF YOU HAVE ANY ADDITIONAL NEEDS. Great flight, crew etc. it wasn’t full so had space to stretch out Only downside was there was no GF option for my partner. We booked through American and it was a Qantas flight so despite contacting both airlines to confirm, she didn’t have a gluten free meal for the 16 hour flight (nor the flight in the other direction). The flight attendants did their best to accommodate but it was not super substantial.

After several delays and being rebooked onto a layer flight, I had to speak to three AA agents for baggage claim to get an attendant. All were in foul mode and reluctant to assist or offer any assistance.

Multiple maintenance delays and the missed and rebooked connection changed gates at least 6 times including one which had us walking 20 minutes to another terminal and then back again. Seated our family of three in different middle seats throughout the plane and then there was an empty seat next to me. Very long travel day which I would have never agreed to if I knew the itinerary would be changed at 5 am, 2 hours before takeoff.

It was as expected for such a short flight. No complaints

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