$149 Find Cheap Flights from Panama City to Florida Keys

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to Florida Keys departing on 3/17. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Florida Keys, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Florida Keys, as well as popular online travel agencies
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Best Florida Keys Flight Deals from Panama City

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours

Miami
Miami1 stop$297
Key West
Key West1 stop$459

Good to know

Low season

April

High season

December

Cheapest flight

$149
Best time to beat the crowds but there is an average 21% increase in price.
Most popular time to fly with an average 8% increase in price.
Flight from Panama City to Miami

FAQs - booking Florida Keys flights

  • How does KAYAK find such low prices on flights from Panama City to Florida Keys?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to Florida Keys.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to Florida Keys?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Panama City to Florida Keys is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to Florida Keys?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Panama City to Florida Keys with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to Florida Keys?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Panama City to Florida Keys up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Top tips for finding cheap flights to Florida Keys

  • Book at least 1 week before departure in order to get a below-average price.
  • High season is considered to be March, April and May. The cheapest month to fly from Panama City is January.

Top 3 airlines serving from Panama City to Florida Keys

 
See real verified KAYAK customer reviews for airlines flying from Panama City to Florida Keys. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Panama City to Florida Keys? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.1
SouthwestOverall score based on 4411 reviews
7.1Food
8.7Crew
7.6Entertainment
8.2Boarding
8.1Comfort
Airline reviews

Flight was awfully bumpy and landing was a bit jolting. I was in the restroom when snacks and drinks were served and was not asked if i wanted any. I had to ask for water finally.

10.0 ExcellentRachel, Jan 2025TPA - MDW
Read more Southwest reviews

Flight was awfully bumpy and landing was a bit jolting. I was in the restroom when snacks and drinks were served and was not asked if i wanted any. I had to ask for water finally.

Excellent! Only question is how we check in at exactly 24 hours in advance and end up at the end of the B boarding group

Crew was great flight was great baggage claim was a failure. It took over 1 hour for bags to arrive. Poor communication poor effort when I spoke to the supervisor about the delay

It went well. Plane wasn't full. Will be great when assigned seating is in place

Planes are aged. The wifi is unreliable and on many fights, no-existent. The flight attendants were very good.

I had a wonderful flight, but the only thing that annoyed me was how crowded TSA was. I still believe airports and all planes work together to bunch everyone together to drive up cost.

Easy to book and to get check in and get on and off.

Excellent experience. WiFi worked on this leg of My trip

Flight was great, but golf bag never made it until later in the day. Even though I had a nonstop flight it was placed on a different one. They made it right with flight credits and I was able to get it the same day.

Everything worked well. Crew was as entertaining as is possible on a plane flight. Southwest still has good legroom:

The young man who was our flight attendant in first class was lazy and did not do his job well at all. Never offered drinks upon boarding - actually I take that back... said "are you okay with water" as if I do not want to get you anything else, only passed the snacks around once, got my drink order wrong and then never offered a second round of drinks. He was the worst I have ever seen on Delta and we fly a lot.

Flight left early and arrived early. the whole trip was excellent.

Newer plane, relatively easy boarding, not a full flight and was told that we could not be moved up because of weight and balance issues. Otherwise, a very good experience.

Other then mechanical/ computer problem and 3.5 hours flight delay the flight was great. I guess that what happened when you fly an old airplane now a day.

Everything was great. Great service, excellent communication, and early arrival

I sat in comfort plus. It was fine. Seats were comfortable. I got drinks and snacks.

Good and consistent Printer in lounge did not work for me :(

Great - This was the last flight before hurricane closures and did a quick turnaround to get the plane heading north. Much appreciated.

I liked the screens in the seat headrest with movies to watch. I didn’t like being forced to check my carryon bag and being told there wasn’t room for my bag - when there were 5 bins sitting empty on takeoff. I didn’t like the “I don’t give a fig” attitude of the flight attendants and the delta gate attendants when I asked why they decided to put me out. They gave me a 1800 number to call but I can’t get a live person on the phone. Customer service is non existent. My business must not be that important to them.

Don't waste your money or points on first class. Delta first class is a joke. The seats were rickety, the food was awful, and nothing worked, wifi, my light, the power plug - and it was dirty - the fold out table was gross. For 2-3 hours, tough it out in Economy.

The flights were terribly delayed and then cancelled which forced us booking another night at the hotel. Very poor management from American Airlines

Crew was late. Baggage was late. 2hs inside the plane waiting fro de-icing and traffic. A 3:30hs flight ended up being almost 6hs inside the airplane.

Checking in at the counter was very disappointing. The lady had a very bad attitude and smart at me. She had no smile, did not greet me by name, or acknowledge me as a valued customer. Poor reflection of the airline.

Miami lounges were overcrowded and we were unable to get in. We only had a short time. But the banks are too tight in all American hubs

I was pleasantly surprised with an upgrade at boarding. I finally had a mostly gluten free food options and a very attentive attendant.

Very poor. Our special services attendant gave us incorrect information. I also was mishandled at landing. There was no wheelchair waiting. I fell deboarding the plane. Appalling!

Boarded over an hour late, no communication, the sign just changed, no attendant to answer questions - she disappeared forever (hiding). Small plane and couldn’t hear the overhead nor understand.

Paid for a window and was assigned to a middle seat with 2 very large people on each side of me. Flight was sold out and I feel I need to be refunded foe paying for a window seat and being put in a middle one..

I had a very unpleasant encounter with one man from customer service: he was extremely rude and miserable. And his condition was reflected on his decision to send me to the worst airport hotel and get an awful flight connection. My hotel shuttle had never arrived and I had to book another hotel. People served by other representatives got a much better treatment and deal.

Very mediocre greeting as we boarded, and the lead flight attendant accent was almost unrecognizable. He joked around a lot, while trying to give the safety demonstration, but did not succeed. My wife’s row was completely missed for beverages and the lead flight attendant didn’t even know that our row was Main cabin and able to have beverages at no charge. We are platinum, 2,000,000 miles on American Airlines and this was not a stellar crew.

Book cheap flights from Panama City to Florida Keys

Recent round-trip flight deals

 
These are the cheapest round-trip flights from Panama City to Florida Keys found on KAYAK in the last 72 hours.
4/1Tue
1 stopDelta
5h 24mECP-MIA
4/2Wed
1 stopDelta
5h 28mMIA-ECP
$297
4/1Tue
2 stopsSouthwest
11h 35mECP-MIA
4/2Wed
1 stopSouthwest
4h 35mMIA-ECP
$302
5/25Sun
1 stopDelta
5h 45mECP-MIA
5/30Fri
1 stopDelta
4h 01mMIA-ECP
$307
3/8Sat
1 stopAmerican Airlines
7h 02mECP-MIA
3/11Tue
1 stopAmerican Airlines
6h 41mMIA-ECP
$312
4/1Tue
2 stopsSouthwest
11h 35mECP-MIA
4/2Wed
2 stopsSouthwest
8h 25mMIA-ECP
$322
3/6Thu
1 stopAmerican Airlines
5h 03mECP-MIA
5/9Fri
1 stopAmerican Airlines
7h 37mMIA-ECP
$337
3/18Tue
1 stopSouthwest
4h 50mECP-MIA
3/22Sat
1 stopSouthwest
6h 40mMIA-ECP
$354
3/18Tue
2 stopsSouthwest
13h 55mECP-MIA
3/22Sat
1 stopSouthwest
6h 40mMIA-ECP
$365
5/7Wed
2 stopsUnited Airlines
19h 46mECP-MIA
5/13Tue
1 stopUnited Airlines
12h 19mMIA-ECP
$524
5/7Wed
2 stopsUnited Airlines
19h 46mECP-MIA
5/13Tue
2 stopsUnited Airlines
25h 11mMIA-ECP
$546

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Recent one-way flight deals

 
Only flying one-way? Below are some of the best one-way flight deals from Panama City to Florida Keys found on KAYAK in the last 72 hours.
3/17Mon
1 stopDelta
6h 45mECP-MIA
$149
3/22Sat
1 stopDelta
4h 54mECP-MIA
$154
3/27Thu
1 stopAmerican Airlines
6h 04mECP-MIA
$157
4/17Thu
2 stopsSouthwest
14h 00mECP-MIA
$159
3/17Mon
1 stopAmerican Airlines
12h 14mECP-MIA
$169
3/12Wed
1 stopAmerican Airlines
5h 13mECP-MIA
$174
3/24Mon
2 stopsDelta
20h 54mECP-MIA
$175
3/12Wed
2 stopsSouthwest
11h 35mECP-MIA
$222
4/28Mon
2 stopsUnited Airlines
24h 10mECP-MIA
$489
4/28Mon
2 stopsUnited Airlines
20h 57mECP-MIA
$503

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Last minute flights from Panama City to Florida Keys

Last minute flight, train and bus deals

 
These last-minute flight deals are the cheapest flights found on KAYAK in the last 72 hours for flights from Panama City to Florida Keys that are departing in the next 10 days.
2/24Mon
multi-stopDelta
5h 06mECP-MIA
3/2Sun
multi-stopDelta
4h 51mMIA-ECP
$587
2/22Sat
multi-stopDelta
5h 31mECP-MIA
3/2Sun
multi-stopDelta
4h 51mMIA-ECP
$607
2/22Sat
multi-stopDelta
6h 21mECP-EYW
3/1Sat
multi-stopDelta
5h 49mEYW-ECP
$629
2/23Sun
multi-stopSouthwest
13h 30mECP-MIA
3/2Sun
multi-stopSouthwest
5h 50mMIA-ECP
$655
2/23Sun
multi-stopSouthwest
13h 30mECP-MIA
3/2Sun
multi-stopSouthwest
8h 05mMIA-ECP
$660
2/21Fri
multi-stopAmerican Airlines
7h 05mECP-MIA
2/23Sun
multi-stopAmerican Airlines
5h 04mMIA-ECP
$667
2/21Fri
multi-stopSouthwest
12h 15mECP-MIA
2/23Sun
multi-stopSouthwest
5h 50mMIA-ECP
$696
2/23Sun
multi-stopAmerican Airlines
7h 08mECP-EYW
2/25Tue
multi-stopAmerican Airlines
6h 50mEYW-ECP
$827
2/22Sat
multi-stopUnited Airlines
11h 08mECP-MIA
3/2Sun
multi-stopUnited Airlines
7h 19mMIA-ECP
$1,297
2/22Sat
multi-stopUnited Airlines
11h 08mECP-MIA
3/2Sun
multi-stopUnited Airlines
10h 09mMIA-ECP
$1,311

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Everything you need to know for your flight to Florida Keys

Information on your arrival and departure airports

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