$124 Find Cheap Flights from Panama City to Florida Keys

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to Florida Keys departing on 3/12. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Florida Keys, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Florida Keys, as well as popular online travel agencies
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Best Florida Keys Flight Deals from Panama City

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours

Miami
Miami1 stop$342
Key West
Key West1 stop$379

Good to know

Low season

February

High season

December

Cheapest flight

$124
Best time to beat the crowds but there is an average 11% increase in price.
Most popular time to fly with an average 8% increase in price.
Flight from Panama City to Miami

FAQs - booking Florida Keys flights

  • How does KAYAK find such low prices on flights from Panama City to Florida Keys?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to Florida Keys.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to Florida Keys?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Panama City to Florida Keys is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to Florida Keys?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Panama City to Florida Keys with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to Florida Keys?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Panama City to Florida Keys up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Top tips for finding cheap flights to Florida Keys

  • Book at least 1 week before departure in order to get a below-average price.
  • High season is considered to be March, April and May. The cheapest month to fly from Panama City is January.

Top airlines flying from Panama City to Florida Keys

 
See real verified KAYAK customer reviews for airlines flying from Panama City to Florida Keys. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Panama City to Florida Keys? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
DeltaOverall score based on 8521 reviews
8.2Boarding
7.3Food
8.0Comfort
8.6Crew
7.9Entertainment
Airline reviews

Flight left early and arrived early. the whole trip was excellent.

10.0 ExcellentNick, Jan 2025TPA - SEA
Read more Delta reviews

Flight left early and arrived early. the whole trip was excellent.

Other then mechanical/ computer problem and 3.5 hours flight delay the flight was great. I guess that what happened when you fly an old airplane now a day.

Don't waste your money or points on first class. Delta first class is a joke. The seats were rickety, the food was awful, and nothing worked, wifi, my light, the power plug - and it was dirty - the fold out table was gross. For 2-3 hours, tough it out in Economy.

Loyal Delta traveler, but last nights flight was a train wreck. Seated in 1B after multiple delays. Then we couldn’t takeoff because of an issue with the passenger that was ‘not in compliance’ and had to deplane along with the threat if they did not deplane, all the passengers would be required to do so. Finally they were escorted off, but the experience threw off the crew. Disruptive for everyone. Service was a mess, televisions didn’t work, bathroom door kept swinging open during the entire flight whenever empty …

My flight was cancelled twice and the third time I tried to rebook it online I cancelled the flight because it looked like I would get a refund to my credit card. Instead I now have a credit. I was also on hold for three hours waiting for a representative and then disconnected. I will never fly delta again.

Awful. Flight was continuously getting delayed and gates kept changing without any reason. Flight was delayed for more then 3 hours

5-hour delay due to storms in Tanoa and airspace restricted by Miami traffic controllers.

I would fly again the whole experience was great. The only feed back I can give that they don't do that American Airlines does is the crew there is more humorous with boarding and thank their passengers. It makes it more fun to fly with them. I would however fly Delta again.

Horrible. This was not first class. This was a connecting flight whi h was late. My original flight never came. I hated the fact that delta gave me a connecting flight from New York to Orlando Florida. No meals and the television screens were not working. There wasn't even any power to charge your phones. This is NOT FIRST CLASS DELTA!!! Do better next time!

They did a fine job. Can't wait to use Delta in the future.

Boarded over an hour late, no communication, the sign just changed, no attendant to answer questions - she disappeared forever (hiding). Small plane and couldn’t hear the overhead nor understand.

Paid for a window and was assigned to a middle seat with 2 very large people on each side of me. Flight was sold out and I feel I need to be refunded foe paying for a window seat and being put in a middle one..

I had a very unpleasant encounter with one man from customer service: he was extremely rude and miserable. And his condition was reflected on his decision to send me to the worst airport hotel and get an awful flight connection. My hotel shuttle had never arrived and I had to book another hotel. People served by other representatives got a much better treatment and deal.

Very mediocre greeting as we boarded, and the lead flight attendant accent was almost unrecognizable. He joked around a lot, while trying to give the safety demonstration, but did not succeed. My wife’s row was completely missed for beverages and the lead flight attendant didn’t even know that our row was Main cabin and able to have beverages at no charge. We are platinum, 2,000,000 miles on American Airlines and this was not a stellar crew.

Two issues. The plane was old and dirty. The armrest looked like an old car that had the vinyl rubbed off. The Seats in these aircraft are about as hard and uncomfortable. I want to tour Italy for a month and I want to buy a one-way ticket to Thailand but I will not sit in the seats these planes have. It is seriously stupid how hard they are.

The flight left a bit late, but arrived close to time expected…With the flight being close to full the crew did well serving drinks to all in a very timely fashion. The flight was a pleasure…

Check bag location is full of rude employees who are unwilling to assist with issues after talking to AA on the phone and relaying messages. The boarding was good. While on the flight it got really hot. Asked flight attendant if there’s a way to drop the temp and make it more comfortable as we are flying from DC to Miami so flying from cold to hot weather. No changes made. Stayed hot and uncomfortable on the plane. When asked again about the AC being down the flight attendant said no the WiFi was down but not the AC. I mentioned it was still hot. No changes.

There was a delay that affected all passengers with connecting flights.

Missed our connector because our first flight was delayed, it was a miracle that we managed to get a second flight. Luggage was lost. People were rude. Flight was delayed and overbooked. Terrible experience. Worst flight I’ve ever had out of hundreds of domestic and international flights. I’ve been on a more comfortable 20 hour flight from Guam than the two hours it took NC TO FL.

Great flight from Charlotte to Orlando. In flight wifi and entertainment was not working til 25 minutes were left in the flight would be my only complaint.

Book cheap flights from Panama City to Florida Keys

Recent round-trip flight deals

 
These are the cheapest round-trip flights from Panama City to Florida Keys found on KAYAK in the last 72 hours.
2/20Thu
1 stopAmerican Airlines
5h 17mECP-MIA
2/24Mon
1 stopAmerican Airlines
7h 26mMIA-ECP
$342
2/22Sat
1 stopDelta
6h 36mECP-MIA
2/28Fri
1 stopDelta
13h 55mMIA-ECP
$354
2/24Mon
1 stopAmerican Airlines
7h 05mECP-MIA
3/1Sat
1 stopAmerican Airlines
5h 09mMIA-ECP
$370
3/25Tue
1 stopDelta
4h 35mECP-EYW
4/1Tue
1 stopDelta
6h 49mEYW-ECP
$379
3/25Tue
2 stopsAmerican Airlines
6h 19mECP-EYW
4/1Tue
1 stopAmerican Airlines
7h 06mEYW-ECP
$384
3/6Thu
1 stopDelta
3h 51mECP-MIA
3/15Sat
1 stopDelta
5h 17mMIA-ECP
$402
2/11Tue
1 stopSouthwest
9h 35mECP-MIA
2/13Thu
1 stopSouthwest
10h 15mMIA-ECP
$409
2/11Tue
2 stopsSouthwest
13h 10mECP-MIA
2/13Thu
1 stopSouthwest
10h 15mMIA-ECP
$414
2/24Mon
2 stopsUnited Airlines
17h 57mECP-MIA
3/1Sat
1 stopUnited Airlines
10h 54mMIA-ECP
$648
2/5Wed
2 stopsUnited Airlines
14h 51mECP-MIA
3/7Fri
1 stopUnited Airlines
18h 30mMIA-ECP
$743

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Recent one-way flight deals

 
Only flying one-way? Below are some of the best one-way flight deals from Panama City to Florida Keys found on KAYAK in the last 72 hours.
3/12Wed
1 stopDelta
4h 54mECP-MIA
$124
2/8Sat
1 stopDelta
6h 37mECP-MIA
$194
2/23Sun
1 stopSouthwest
7h 10mECP-MIA
$206
3/12Wed
2 stopsSouthwest
11h 35mECP-MIA
$211
2/8Sat
2 stopsSouthwest
8h 40mECP-MIA
$234
2/23Sun
2 stopsSouthwest
13h 30mECP-MIA
$266
3/12Wed
3 stopsUnited Airlines
27h 04mECP-MIA
$479

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Last minute flights from Panama City to Florida Keys

Last minute flight, train and bus deals

 
These last-minute flight deals are the cheapest flights found on KAYAK in the last 72 hours for flights from Panama City to Florida Keys that are departing in the next 10 days.
1/22Wed
multi-stopAmerican Airlines
4h 48mECP-MIA
2/22Sat
multi-stopAmerican Airlines
6h 57mMIA-ECP
$593
1/22Wed
multi-stopDelta
4h 14mECP-MIA
2/22Sat
multi-stopDelta
7h 05mMIA-ECP
$626
1/22Wed
multi-stopAmerican Airlines
9h 01mECP-MIA
2/22Sat
multi-stopAmerican Airlines
6h 57mMIA-ECP
$769
1/22Wed
multi-stopUnited Airlines
14h 05mECP-MIA
2/22Sat
multi-stopUnited Airlines
13h 52mMIA-ECP
$856

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Everything you need to know for your flight to Florida Keys

Information on your arrival and departure airports

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