$428 Find Cheap Flights from Myrtle Beach to Panama

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to Panama departing on 5/16. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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Best Panama Flight Deals from Myrtle Beach

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours

Panama City
Panama City2 stops$428

Cheap Flight Deals from Myrtle Beach to Panama (MYR-PA0)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to Panama that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.

Recent round-trip flight deals from Myrtle Beach to Panama

Recommended round-trip deals departing in the coming months from the most popular airlines that fly from Myrtle Beach to Panama.
Discover the best prices for you by selecting your travel dates on KAYAK.
Choose your dates
American Airlines Logo
3:56 pm - 12:19 pmMYR-PTY
21h 23m2 stops
American Airlines Logo
1:20 pm - 8:30 amPTY-MYR
18h 10m2 stops
$428American Airlines
Find Deal
Fri, May 16 - Fri, May 23
American Airlines Logo
6:16 pm - 12:54 pmMYR-PTY
19h 38m2 stops
American Airlines Logo
3:05 pm - 9:40 amPTY-MYR
17h 35m2 stops
$460American Airlines
Find Deal
Sat, Jul 5 - Sat, Jul 12
 Logo
6:00 am - 12:10 amMYR-PTY
19h 10m2 stops
 Logo
3:20 am - 9:05 pmPTY-MYR
16h 45m2 stops
Fri, May 16 - Thu, May 22
American Airlines Logo
6:05 pm - 12:19 pmMYR-PTY
19h 14m2 stops
American Airlines Logo
1:20 pm - 2:17 pmPTY-MYR
23h 57m2 stops
$550American Airlines
Find Deal
Sun, May 4 - Sat, May 10
United Airlines Logo
11:08 am - 7:31 pmMYR-PTY
9h 23m1 stop
United Airlines Logo
10:55 pm - 9:07 amPTY-MYR
9h 12m1 stop
$683United Airlines
Find Deal
Fri, May 16 - Fri, May 23
 Logo
5:32 pm - 8:19 pmMYR-PTY
27h 47m1 stop
 Logo
7:55 am - 9:05 pmPTY-MYR
12h 10m2 stops
Fri, May 16 - Fri, May 23
 Logo
6:30 am - 7:15 pmMYR-PTY
13h 45m2 stops
 Logo
3:25 am - 10:54 pmPTY-MYR
18h 29m2 stops
Sat, Jul 5 - Fri, Jul 11
Delta Logo
1:06 pm - 7:02 pmMYR-PTY
6h 56m1 stop
Delta Logo
2:12 pm - 11:39 pmPTY-MYR
8h 27m1 stop
$785Delta
Find Deal
Sat, Jul 5 - Sat, Jul 12
United Airlines Logo
11:08 am - 7:31 pmMYR-PTY
9h 23m1 stop
United Airlines Logo
10:55 pm - 11:01 amPTY-MYR
11h 06m1 stop
$847United Airlines
Find Deal
Thu, May 15 - Thu, May 22
Delta Logo
6:00 am - 12:55 pmMYR-PTY
7h 55m1 stop
Delta Logo
8:00 am - 4:33 pmPTY-MYR
7h 33m1 stop
$897Delta
Find Deal
Sun, May 4 - Sat, May 10

KAYAK's insights & trends for Myrtle Beach to Panama flights

Get data-powered insights and trends into flights from Myrtle Beach to Panama to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest time of day to fly to Panama?

The average price for all round-trip flights from Myrtle Beach to Panama depending on the time of departure, clicked by users on KAYAK in the last 2 weeks.
The cheapest time of day to fly to Panama is generally in the morning, when round-trip flights cost $572 on average. The most expensive time of day to fly to Panama is generally in the morning, which is peak travel time and where the average cost of a ticket is $572.

What is the cheapest month to fly from Myrtle Beach to Panama?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Myrtle Beach to Panama, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.
The cheapest month for flights from Myrtle Beach to Panama is June, when tickets cost $417 (return) on average. On the other hand, the most expensive months are March and February, when the average cost of round-trip tickets is $788 and $777 respectively.

What’s the cheapest day of the week to fly from Myrtle Beach to Panama?

The average price of all round-trip flights from Myrtle Beach to Panama clicked on KAYAK for each day over the last 12 months.
If your flying dates are flexible, you should consider flying to Panama on a Wednesday, as we generally find the cheapest rates on that day for this route. On the other hand, Thursday is the most expensive day to fly from Myrtle Beach to Panama. For your return ticket, we recommend flying on a Monday and avoiding Wednesdays for the best deals.

Good to know

Low season

March

High season

January

Cheapest flight

$428
Best time to beat the crowds but there is an average 31% increase in price.
Most popular time to fly and prices are also 5% lower on average.
Flight from Myrtle Beach to Panama City

FAQs - booking Panama flights

  • How does KAYAK find such low prices on flights from Myrtle Beach to Panama?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to Panama.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to Panama?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Myrtle Beach to Panama is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to Panama?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Myrtle Beach to Panama with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to Panama?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Myrtle Beach to Panama up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Top airlines flying from Myrtle Beach to Panama

Need help choosing which airline to fly with from Myrtle Beach to Panama? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
DeltaOverall score based on 7898 reviews
7.9Entertainment
8.2Boarding
7.9Comfort
7.3Food
8.5Crew
Airline reviews

Simply outstanding. Their new lounge for Delta One customers is a cut above the rest.

10.0 ExcellentSunderesh, Mar 2025AUS - BOS
Read more Delta reviews

Simply outstanding. Their new lounge for Delta One customers is a cut above the rest.

The Dekta Rep that checked us in was great. She's very personable, pleasant, and can tell she enjoys her job.

After a 5 hour delay waiting at the gate (3 delays adding up) with no clear reason provided, we finally boarded flew 3/4 of the way to Toronto then were turned back to New York. As we neared New York, the pilot declared that it was his fault, something to do with timing and him not being allowed into the country???? How could the airline let his happen? They had hours to prepare and make sure they had a crew available for the flight! We ended up in Toronto a day late with no sleep.

The plane was old with small storage areas that had problems closing/latching and not enough storage for everyone, and worn, damaged seats. Service was great but feel a little unsafe on such well used planes.

Terrible and im avoiding them in the future. My initial flight was delayed causing me to rebook my flight and when speaking with the representative to rebook I explained this is the second time my flights were delayed and they did nothing to help me. I wasn't booked to comfort plus or given a voucher or anything. I was almost late for my meeting that I needed to attend on Monday because of the games delta played delaying my flights even more and putting me in the very back of the plane next to an extremely intoxicated passenger

Friendly flight attendants, smooth 8-9 hours flight. Economy seats are small and uncomfortable as usual.

Flights on time. .Ride was as comfortable as can be expected in steerage. Luggage arrived at destination. Attendants were fairly friendly.

Great staff. Wifi is terrible. Signing up for skylines is a painstaking process. Had to call customer service just to get my flight itinerary and confirmation sent to me. Consistent delays. A well staffed company that is run so poorly. Upper management needs to be renewed.

The WiFi didn't seem as fast as it normally is

Bathrooms dirty sinks clogged. No one seemed to clean them. Plane very old

The trip was very smooth and they provided great customer service

The plane was late and then sat on the runway for almost 45 minutes before taking off.

Wonderful as usual except for other guests that were unruly and not kept in check by the Crew.

The flight was initially delayed, then cancelled. American Airlines says the cancellation was weather related, though the actual weather was not bad in both Washington and Providence and between. There were very few cancellations that day. In fact, AA2120 from Washington, DC to Boston flew with a minor delay at about the same time. So, the weather somehow affected only this particular flight AA5230. The next available flight was the following morning. The American Airlines refused to reimburse accommodation (hotel at DCA)

I have long legs, my foot was out in the aisle and when a flight attendant came walking by and I didn't notice, instead of saying "excuse me" or anything like that, she kicked my foot. Extremely rude

One bottle of water and a package of cookies for comfort plus. We had to literally beg a flight attendant for an extra bottle of water later in the flight due to feeling dehydrated.

Fine. On time, cabin service was fine, bag arrived. All good. Flying into DCA so did not collide with any helicopters, which is also good. Horrid incident that could have and should have been prevented.

Cabin was roomy enough to easily slide my carry on under the seat in front of me!

Everything was fine. Flight boarded and departed on time. Seating was spacious enough for my carryon to fit under the seat in front of me. No complaints at all. Flight even arrived early.

We kept being told that the flight was full and that all overhead compartments were full and therefore had to check in our hand luggage. We were some of the last people to board and noticed that there was still sufficient space in the overhead compartments. We were obliged to check in hand luggage when there was space and so had to wait at luggage retrieval which took a while to then noticed damage to our luggage - not a great experience!

Everything you need to know for your flight from Myrtle Beach to Panama

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