$375 Find Cheap Flights from Manchester to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Manchester to South America departing on 3/1. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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Best South America Flight Deals from Manchester

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours

Lima
Lima2 stops$913
Buenos Aires
Buenos Aires2 stops$1,375
Sao Paulo
Sao Paulo1 stop$863
Cartagena
Cartagena2 stops$876
Rio de Janeiro
Rio de Janeiro2 stops$703
Quito
Quito2 stops$752
Guayaquil
Guayaquil2 stops$959

Good to know

Cheapest flight

$375
Flight from Manchester to Medellín

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Manchester to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Manchester to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Manchester to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Manchester to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Manchester to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Manchester to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Manchester to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Manchester to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Top tips for finding cheap flights to South America

  • High season is considered to be January, February and December. The cheapest month to fly from Manchester is January.
  • Morning departure is around 38% cheaper than an evening flight, on average*.
*Average of the lowest prices shown in KAYAK’s search results for departures within the next 30 days

Top airline flying from Manchester to South America

Need help choosing which airline to fly with from Manchester to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 10000 reviews
7.5Boarding
6.5Food
7.2Comfort
7.0Entertainment
8.0Crew
Airline reviews

This was a pleasant, short flight and the crew was friendly.

10.0 ExcellentBenjamin, Jan 2025DFW - TUL
Read more American Airlines reviews

This was a pleasant, short flight and the crew was friendly.

Very poor. Our special services attendant gave us incorrect information. I also was mishandled at landing. There was no wheelchair waiting. I fell deboarding the plane. Appalling!

It was good. It’s been a long time since my wife and I fly any where and things have changed. Our trip was to see our new grandson. We fly economy and that was not good for my bad back. It was a quick flight but uncomfortable.

I paid for what I got which was cheap, I brought my own entertainment. I knew what to expect, so I could be prepared. If you’re flying economy, check in early like me. I have no problems with my flight, was on time, staff were friendly, and overall good experience.

Boarded over an hour late, no communication, the sign just changed, no attendant to answer questions - she disappeared forever (hiding). Small plane and couldn’t hear the overhead nor understand.

Service in first class no longer exists on American Airlines .

Customer service in first class does not exist on American Airlines

I never have a good experience with American and this was no different. The airplane was INCREDIBLY hot. Like unbearably so. Everyone was fanning themselves with pamphlets and sweating. When someone asked the flight attendant to turn down the temperature they were told there was nothing the crew could do. Once we pushed back from the gate we then had to wait an hour to take off and the communication from the crew was not good. People were getting up this whole time and a man was even in the bathroom when we took off. Once we landed at our destination we waited another 30 minutes at the gate to deplane with, again, no communication from the crew as to what was going on.

Flight was delayed due to a steering issue with plane. The delay caused me to miss the connecting flight. The delay caused me to spend an extra 21 hours in airports and flights to get to my destination. The plane issue obviously should have been found and fixed before we even boarded. Ridiculous.

First, to be fair, the flight was on time and the trip through the air was relatively smooth. But the flight was full, and they were checking carryons. As this process went on, the crew got increasingly rude and overbearing. During the drink service, a young girl (maybe 9) who had gotten up to use the lavatory got stuck behind the cart. At some point, she started feeling fearful and overwhelmed. Passengers noticed this and asked the crew to let her return to her seat. They refused. Then she started crying, and they still refused to move the cart forward to let her sit. The poor girl was trying to be brave and compose herself. The crew handled the situation terribly and with zero grace or decency. That episode, to me, encapsulates AA’s attitude toward its passengers. Disgraceful. The plane itself was cramped and miserable, as usual. There was zero inflight media or entertainment, other than the lane and borderline inappropriate jokes the steward made during the safety briefing. Then, of course, it took the better part of an hour for the checked bags to show up at the carousel. AA is no better than the el cheapo airlines these days and a far, far cry from its former self.

Book cheap flights from Manchester to South America

Recent round-trip flight deals

3/20Thu
2 stopsAmerican Airlines
19h 12mMHT-BOG
3/27Thu
2 stopsAmerican Airlines
17h 00mBOG-MHT
$542
3/20Thu
2 stopsAmerican Airlines
18h 59mMHT-BOG
3/26Wed
2 stopsAmerican Airlines
15h 25mBOG-MHT
$553
3/20Thu
1 stopUnited Airlines
11h 20mMHT-BOG
3/27Thu
1 stopUnited Airlines
10h 45mBOG-MHT
$579
3/20Thu
2 stopsUnited Airlines
30h 05mMHT-BOG
3/27Thu
1 stopUnited Airlines
10h 45mBOG-MHT
$643
5/24Sat
2 stopsUnited Airlines
27h 20mMHT-MDE
5/31Sat
2 stopsUnited Airlines
23h 58mMDE-MHT
$656
3/18Tue
2 stopsUnited Airlines
26h 35mMHT-GIG
3/24Mon
2 stopsUnited Airlines
20h 45mGIG-MHT
$703
3/20Thu
1 stopUnited Airlines
11h 20mMHT-BOG
3/26Wed
2 stopsUnited Airlines
19h 03mBOG-MHT
$776
3/16Sun
2 stopsAmerican Airlines
23h 48mMHT-GIG
3/23Sun
2 stopsAmerican Airlines
24h 41mGIG-MHT
$803
2/14Fri
2 stopsAmerican Airlines
22h 38mMHT-GIG
2/20Thu
2 stopsAmerican Airlines
16h 06mGIG-MHT
$853
2/14Fri
3 stops
23h 30mMHT-GIG
2/20Thu
2 stops
30h 45mGIG-MHT
$863

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Recent one-way flight deals

3/1Sat
2 stopsUnited Airlines
16h 05mMHT-MDE
$375
2/27Thu
2 stopsUnited Airlines
28h 35mMHT-MDE
$402
3/7Fri
2 stopsUnited Airlines
28h 35mMHT-MDE
$455
3/8Sat
2 stopsUnited Airlines
16h 05mMHT-MDE
$505
3/12Wed
2 stopsUnited Airlines
25h 20mMHT-EZE
$818
3/16Sun
2 stopsUnited Airlines
37h 50mMHT-EZE
$848
3/14Fri
2 stopsUnited Airlines
23h 20mMHT-EZE
$868
3/6Thu
2 stopsUnited Airlines
16h 05mMHT-MDE
$883
3/14Fri
3 stops
31h 25mMHT-EZE
$2,711

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Everything you need to know for your flight to South America

Information on your arrival and departure airports

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