$51 Find Cheap Flights from Louisville to South Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Louisville to South Carolina departing on 5/2. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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KAYAK searches hundreds of travel sites at once for deals on flights to South Carolina

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Louisville to South Carolina.
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Louisville to South Carolina.
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Best South Carolina Flight Deals from Louisville

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours

Charleston
Charlestonnonstop$107
Myrtle Beach
Myrtle Beachnonstop$78
Greenville
Greenville1 stop$237
Columbia
Columbia1 stop$259
Florence
Florence1 stop$470

Cheap Flight Deals from Louisville to South Carolina (SDF-USSC)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Louisville to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.

Recent round-trip flight deals from Louisville to South Carolina

Recommended round-trip deals departing in the coming months from the most popular airlines that fly from Louisville to South Carolina.
Discover the best prices for you by selecting your travel dates on KAYAK.
Choose your dates
12:04 pm - 1:32 pmSDF-MYR
1h 28mnonstop
2:17 pm - 3:52 pmMYR-SDF
1h 35mnonstop
$78Allegiant Air
Find Deal
Sat, May 24 - Sat, May 31
4:45 pm - 6:23 pmSDF-MYR
1h 38mnonstop
2:22 pm - 3:57 pmMYR-SDF
1h 35mnonstop
Sat, May 17 - Sat, May 24
4:45 pm - 6:23 pmSDF-MYR
1h 38mnonstop
1:50 pm - 3:50 pmMYR-SDF
2h 00mnonstop
$89Spirit Airlines
Find Deal
Sat, May 10 - Sat, May 17
8:41 am - 10:19 amSDF-MYR
1h 38mnonstop
1:50 pm - 3:50 pmMYR-SDF
2h 00mnonstop
$90Spirit Airlines
Find Deal
Sat, May 3 - Sat, May 10
8:35 pm - 10:11 pmSDF-CHS
1h 36mnonstop
7:05 am - 8:52 amCHS-SDF
1h 47mnonstop
$107Breeze Airways
Find Deal
Fri, May 9 - Mon, May 12
8:35 pm - 10:11 pmSDF-CHS
1h 36mnonstop
7:05 am - 8:52 amCHS-SDF
1h 47mnonstop
$118Breeze Airways
Find Deal
Mon, Jul 14 - Fri, Jul 18
7:30 am - 12:21 pmSDF-CHS
4h 51m1 stop
4:24 pm - 9:03 pmCHS-SDF
4h 39m1 stop
$199American Airlines
Find Deal
Wed, Apr 30 - Wed, May 7
7:34 am - 3:28 pmSDF-MYR
7h 54m2 stops
7:54 pm - 12:18 amMYR-SDF
4h 24m1 stop
$206American Airlines
Find Deal
Sat, May 10 - Sat, May 17
5:30 pm - 9:31 pmSDF-CHS
4h 01m1 stop
3:51 pm - 9:48 pmCHS-SDF
5h 57m1 stop
$218Delta
Find Deal
Sat, Apr 26 - Sat, May 3
6:00 am - 11:39 amSDF-MYR
5h 39m1 stop
6:00 am - 11:55 amMYR-SDF
5h 55m1 stop
$219Delta
Find Deal
Wed, May 21 - Tue, May 27

KAYAK's insights & trends for Louisville to South Carolina flights

Get data-powered insights and trends into flights from Louisville to South Carolina to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest Louisville to South Carolina flight route?

The cheapest price for flight routes found by users searching on KAYAK in the last 2 weeks for round-trip flights from Louisville to South Carolina.
The cheapest ticket to South Carolina from Louisville found in the last 72 hours was to Myrtle Beach, at $83 round-trip. The most popular route is from Louisville (SDF) to Myrtle Beach (MYR), and the cheapest round-trip airline ticket found on this route in the last 72 hours was $83.

What is the cheapest time of day to fly to South Carolina?

The average price for all round-trip flights from Louisville to South Carolina depending on the time of departure, clicked by users on KAYAK in the last 2 weeks.
The cheapest time of day to fly to South Carolina is generally at night, when round-trip flights cost $106 on average. Morning departures are around 7% cheaper than evening flights, on average. The most expensive time of day to fly to South Carolina is generally in the evening, which is peak travel time and where the average cost of a ticket is $322.

What is the cheapest month to fly from Louisville to South Carolina?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Louisville to South Carolina, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.
The cheapest month for flights from Louisville to South Carolina is August, when tickets cost $120 (return) on average. On the other hand, the most expensive months are December and February, when the average cost of round-trip tickets is $378 and $354 respectively.

What’s the cheapest day of the week to fly from Louisville to South Carolina?

The average price of all round-trip flights from Louisville to South Carolina clicked on KAYAK for each day over the last 12 months.
If you are looking for a flight deal from Louisville to South Carolina, look for departures on Fridays and avoid leaving on a Saturday, as it's usually the priciest day. When flying back from South Carolina, Friday is the cheapest day to fly and Sunday is the most expensive.

How far in advance should I book a flight from Louisville to South Carolina?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Louisville to South Carolina, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.
To get a below average price on the flight from Louisville to South Carolina, you should book around 2 weeks before departure. For the absolute cheapest price, our data suggests you should book 6 weeks before departure.

Good to know

Low season

January

High season

June

Cheapest flight

$51
Best time to beat the crowds but there is an average 7% increase in price.
Most popular time to fly with an average 9% increase in price.
Flight from Louisville to Charleston

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Louisville to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Louisville to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Louisville to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Louisville to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Louisville to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Louisville to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Louisville to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Louisville to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Top tips for finding cheap flights to South Carolina

  • Looking for a cheap flight? 25% of our users found tickets from Louisville to the following destinations at these prices or less: Charlotte $149 one-way - $355 round-trip

Top 5 airlines serving from Louisville to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Louisville to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Louisville to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.1
Breeze AirwaysOverall score based on 157 reviews
8.3Boarding
6.7Food
8.8Crew
6.6Entertainment
8.2Comfort
Airline reviews

My original booking was a nonstop flight. It got changed to a flight with a 6vhour layover that became a 7+ hour lay over. I'll never fly this airline again after this roundtrip is over.

2.0 MediocreAnonymous, Mar 2025TPA - PVD
Read more Breeze Airways reviews

My original booking was a nonstop flight. It got changed to a flight with a 6vhour layover that became a 7+ hour lay over. I'll never fly this airline again after this roundtrip is over.

I was surprised at how wonderful it was. The aircraft was clean. The crew was warm and welcoming and as a result the passengers were friendly. One warning the only free thing was water. I kind of liked picking wet hat I was willing to pay for and what I was willing to skip.

The flight wasn’t big on frills, which is fine with me. I flew into Islip MacArthur Airport, which saved me from having to go through LaGuardia to visit friends on Long Island. It was inexpensive and super convenient!

Great experience! This was my first time flying with them and I could not have been happier.

Airplane was newer and very clean, lots of space. Crew was great. There was no food and entertainment but that was expected so not an issue.

I like that the price is right! The airplane is clean and the staff is friendly. We landed safely, so that is always a gold star in my book! Great job!

Purposely delayed the flight by 2 hours and 58 minutes so that they would not have to give me the FAA mandated refund for a delay of 3 hours. Offered flight credit instead. All that is offered on board is water and coffee, everything else costs money. They charge you for carry on and checked bags. Would not fly again.

nice flight. no frills but a 3 hour flight I caught up on my sleep. Stan O

First time flying Breeze, was very impressed. I will use Breeze again.

The flight was rescheduled and canceled. I had to go with another airline last minute to honor my school commitment. The reimbursement is a joke -$150 for a one way plane ticket.

Simply outstanding. Their new lounge for Delta One customers is a cut above the rest.

The Dekta Rep that checked us in was great. She's very personable, pleasant, and can tell she enjoys her job.

The plane was old with small storage areas that had problems closing/latching and not enough storage for everyone, and worn, damaged seats. Service was great but feel a little unsafe on such well used planes.

Terrible and im avoiding them in the future. My initial flight was delayed causing me to rebook my flight and when speaking with the representative to rebook I explained this is the second time my flights were delayed and they did nothing to help me. I wasn't booked to comfort plus or given a voucher or anything. I was almost late for my meeting that I needed to attend on Monday because of the games delta played delaying my flights even more and putting me in the very back of the plane next to an extremely intoxicated passenger

Flights on time. .Ride was as comfortable as can be expected in steerage. Luggage arrived at destination. Attendants were fairly friendly.

Great staff. Wifi is terrible. Signing up for skylines is a painstaking process. Had to call customer service just to get my flight itinerary and confirmation sent to me. Consistent delays. A well staffed company that is run so poorly. Upper management needs to be renewed.

The WiFi didn't seem as fast as it normally is

Thank you for not flipping the plane on the run way. You guys get a 5 star rating for the flight!!!

The crew was wonderful and attentive. The seats near exit row were restrictive. Offer healthy snacks please

Delta is a premier airline so my expectations are most always met.

Easiest flights I’ve ever taken. Plane was comfortable without overly crowded seating.

Terrible. Still have not received the refund from them. They sent it to some account that I don't even know. Spoke with costumer service and they are unable to help.

I didn’t like it at all. I miss my second flight because of the delay on Allegiant Air now I m stuck in MCO.

Good, but a bit late on take off after loading. Don't like charging for carry ons!

First time flying with them and will definitely fly again in the future. Crew was so nice and friendly, fought was seamless. They are simple planes, no entertainment, but it’s fine for a short flight or if you have personal devices Rates are competitive, and they did so well with keeping the flight on time after a tropical storm, where other airlines had delays and cancellations.

They boarded passengers that sat in the back of the plane first, making boarding very efficient.

I didn't even take this flight. My plans changed and I couldn't get ahold of customer service and the website kept breaking down during the attempt to change the flight. I wound up taking another airline entirely and eating the cost.

The worst flying experience ever 3 delays. No accommodations. Had to deboard the plane after being delayed.

Posted a 20minute delay but didn’t delay at all. Caused boarding issues and confusion. Also, didn’t release baggage. Took over an hour and 20 minutes to get luggage.

Flight was good, boarding was a breeze, flight attendants were friendly and professional. There was a medical issue with another passenger and the crew handled it in a calm and professional way.

The trip was very smooth and they provided great customer service

The plane was late and then sat on the runway for almost 45 minutes before taking off.

Wonderful as usual except for other guests that were unruly and not kept in check by the Crew.

The flight was initially delayed, then cancelled. American Airlines says the cancellation was weather related, though the actual weather was not bad in both Washington and Providence and between. There were very few cancellations that day. In fact, AA2120 from Washington, DC to Boston flew with a minor delay at about the same time. So, the weather somehow affected only this particular flight AA5230. The next available flight was the following morning. The American Airlines refused to reimburse accommodation (hotel at DCA)

I have long legs, my foot was out in the aisle and when a flight attendant came walking by and I didn't notice, instead of saying "excuse me" or anything like that, she kicked my foot. Extremely rude

One bottle of water and a package of cookies for comfort plus. We had to literally beg a flight attendant for an extra bottle of water later in the flight due to feeling dehydrated.

Fine. On time, cabin service was fine, bag arrived. All good. Flying into DCA so did not collide with any helicopters, which is also good. Horrid incident that could have and should have been prevented.

Cabin was roomy enough to easily slide my carry on under the seat in front of me!

Everything was fine. Flight boarded and departed on time. Seating was spacious enough for my carryon to fit under the seat in front of me. No complaints at all. Flight even arrived early.

We kept being told that the flight was full and that all overhead compartments were full and therefore had to check in our hand luggage. We were some of the last people to board and noticed that there was still sufficient space in the overhead compartments. We were obliged to check in hand luggage when there was space and so had to wait at luggage retrieval which took a while to then noticed damage to our luggage - not a great experience!

I book a filght for me and my daughter from Miami home to Las Vegas and getting her checked in was awful the lady at the baggage check in was horrible!!! She was the rudest person I have ever encountered in my entire life!!!! My daughter dose not speak Spanish and so I was trying to translate for her but the woman would not let me so my daughter was 100 💯 confused because she could not understand what was going on or being said at all horrible absolutely horrible and rude extremely stressful worst experience ever!!!!!!! And then we were actually told by other air port staff not to complain because if we did sprint would make sure we miss our flight ✈️ that they do it all the time 😧

Terrible! They kept postponing and finally canceled our flight. They canceled so late. We had no other options but to drive to a different city and try to find a new flight to get onto our cruise. We still aren’t there yet and might not make it.

The flight was on time. The seats are very narrow.

My only complaint is that the standing recline. I wasn’t aware of that when I booked the ticket.

Unclear pricing; ended up being charged an extra $52 just to get onboard

Spirit is awful. Too expensive for what you get. Stop nickel and diming.

No leg room AT all extremely uncomfortable flight water even cost 5 dollars

Seats are poor. They do not lean back. They do not even have pockets on the back, making it impossible to store a phone or a coke bottle. If you opt for basic economy cheap seats, they stick you always in the middle or window seat, even though there are unoccupied seats on the aisle. And then there is the nickel and diming. No carry-ons. And checking your carry-on is $70. At the end there is no price advantage but there is plenty of aggravation.

Not good. No updates regarding the flight status until after the fact on the delays and then a cancellation.

Flight crew was great. Spirit leaves a lot to be desired in terms of comfort.

Everything you need to know for your flight from Louisville to South Carolina

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