$65 Find Cheap Flights from St. Louis to South Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from St. Louis to South Carolina departing on 1/18. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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These are the airlines KAYAK users have selected most often from within our search results in flight searches from St. Louis to South Carolina, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from St. Louis to South Carolina, as well as popular online travel agencies
In the last 7 days travelers have searched 41,299,237 times on KAYAK, and here is why:

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Best South Carolina Flight Deals from St. Louis

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours

Charleston
Charleston1 stop$185
Myrtle Beach
Myrtle Beach1 stop$217
Greenville
Greenville1 stop$286
Columbia
Columbia1 stop$248

Good to know

Low season

January

High season

May

Cheapest flight

$65
Best time to beat the crowds with an average 19% drop in price.
Most popular time to fly and prices are also 2% lower on average.
Flight from St. Louis to Charlotte

FAQs - booking South Carolina flights

  • How long is the flight to South Carolina from St. Louis?

    Flights to Charleston2h 10m
  • What is the cheapest flight to South Carolina from St. Louis?

    The cheapest ticket to South Carolina from St. Louis found in the last 72 hours was $65 one-way, and $118 round-trip. The most popular route is from St. Louis to Charleston, and the cheapest round-trip airline ticket found on this route in the last 72 hours was $91.

  • How does KAYAK find such low prices on flights from St. Louis to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from St. Louis to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from St. Louis to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from St. Louis to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from St. Louis to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from St. Louis to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from St. Louis to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from St. Louis to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Top tips for finding cheap flights to South Carolina

  • Looking for a cheap flight? 25% of our users found tickets from St. Louis to the following destinations at these prices or less: Charlotte $187 one-way - $374 round-trip
  • Book at least 1 week before departure in order to get a below-average price.
  • High season is considered to be January, November and December. The cheapest month to fly from St. Louis is January.
  • Morning departure is around 20% cheaper than an evening flight, on average*.
See more tips
*Average of the lowest prices shown in KAYAK’s search results for departures within the next 30 days

Top 5 airlines serving from St. Louis to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from St. Louis to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from St. Louis to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.1
SouthwestOverall score based on 4854 reviews
7.2Food
8.1Comfort
8.7Crew
8.2Boarding
7.7Entertainment
Airline reviews

Crew was great flight was great baggage claim was a failure. It took over 1 hour for bags to arrive. Poor communication poor effort when I spoke to the supervisor about the delay

10.0 ExcellentRoxann, Dec 2024MCO - STL
Read more Southwest reviews

Crew was great flight was great baggage claim was a failure. It took over 1 hour for bags to arrive. Poor communication poor effort when I spoke to the supervisor about the delay

Much better than the.last. flight on SW on Thanksgiving day

Fine, but how to board on SW versus othrr airlines, is just lame. Goood staff though and all was solid otherwise.

The movies using Southwest WiFi kept pausing and I had to restart multiple times.

It went well. Plane wasn't full. Will be great when assigned seating is in place

Everything was great except the food. The pretzels are really crappy.

For the first time in a long time we had a flawless experience with Southwest. Both flights were early and no mechanical errors at all. We were shocked and pleasantly surprised 😮.

It was fine. For some reason the flight was much longer than usual. It may have been explained, but I had noise cancelling earbuds on and missed a couple of announcements. The crew was fine, but there was a flight attendant who kept telling dumb jokes, occasionally one I found distasteful. This was my second time with him, but luckily it was a late flight so he didn't do as many. But I heard all of today's jokes twice, which was two times too many. Good takeout and landing.

One of the crew performed a hilarious skit to accompany the standard instructions. Passengers enjoyed it so much they applauded at the end!

First, my flight was a usual flight nothing exceptional or unexpected. Over all it was a normal, good flight! Second, your questionaire is wholly lacking in the proper options to which one can answer a question. Often on short flights, there is no food let alone entertainment so why isn't that reflected in your questionaire? A simple "not applicable" would cover that issue appropriately but no, your form arbitrarily enters an answer based on the initial assessment which normally isn't factual. Until you provide an accurate means of assessing flights, I'll no longer be completing of these unimpressive and misleading assessements. Thank you!

The dear was very limited in space. I could put my water bottle in seat basket. Also, there was no inflight entertainment in the delta app?

Typically I give delta excellent reviews. Our flight was delayed 2hrs, I was one of the fortunate ones who were able to get to my connecting flight. Also, annoying that on the connecting flight boarding personnel make me put away a small bag into my carryon. It small enough to put in back pocket seat, why hold me and the line up to just push it into my carryon.

Everything was great. Great service, excellent communication, and early arrival

Delta flight attendants poorly managed the boarding process and overhead storage. My bag was checked last minute and no claim ticket was provided. My bag is now lost. Complete incompetence by all flight crew involved.

Inexpensive, got an exit row aisle aeat with no middle passenger, bought a great breakfast sandwich, flight comfortable & arrived ahead of schedule.

Customer service at the gate in the flight was exceptional. On time. Aircraft and seat was decent. Thanks Delta. 💗

It was terrible, if they ran flights on time it would make a big difference.

Great flight. On-time, comfortable, clean aircraft, and offered snacks pre-flight to plan for a potentially turbulent route. I wish there was Wi-Fi an all Delta Aircrafts but for a short flight this is not much of a problem.

Delta seems to be improving in many areas, except they are super bad with the food available. Bring back normal food service on long flights.

If I pay extra for "comfort+" I expect leg room where I can stretch my legs. I was seated with an attendant's seat blocking my feet. Knee space was fine but my feet had less room than the non-"comfort+" seats. Also, don't go cheap on food when you have flights of 3+ hours. It's insulting.

We were delayed 3x and because I didn’t purchase my tickets directly from United Airlines I was told I Have to take care of it myself so I called Underpricer and they helped me but before I changed my flights I took the risk of sticking by what my tickets were and was lucky to have gotten on the original all flight with only 15 mins before take off. not sure if I will do this again

The planes are so dirty! Food crumbs and finger print smudges, Dust over the vents and carpet stains. It’s disgusting.

Everything good until we waited for jet bridge at SFO. Then pilot gets on speaker & said it won’t reach plane- too short, need to go to different gate. Then 5 min later, adjusted plane/jetbridge & all ok?!?

David went above and beyond to make our flight the best that it could be

Was a pain having to leave the plane and reboard but glad the plane was fixed

How badly can you screw up baggage claim? We were told to go to baggage claim too for our bags from this flight. Another flights bags were there. They finished up. More bags from a different flight arrived. Our bags did not Finally the baggage claim belt stopped working and and are flight was still listed on the arrivals for that baggage claim 2. And then nothing It turns out that they had been delivered not only the United baggage claim but far away on a Delta baggage claim No I never told us. It was only the people looking around who had been on the flight But I’m sure there was plenty of time for the employees to raffle through the bags and steal whatever they wanted

The bag drop personal were not helpful. There was no food on the flight. Boeing aircraft, lousy as always. Everything else was fine.

We had to wait almost an hour for the wheelchair porter to be ready to pick up my mother. And when she arrived in Newark airport the porter was not there and she started walking with her cane and her poor mobility. When the Newark porter found her they didn't want to transfer her bags to the wheelchair for her.

I was forced to check my carry-on backpack despite there being space - but it came out on the baggage carousel so fast it didn't even delay my pickup. Otherwise a good flight. Boarding began early (which was disadvantageous for me) but fine.

Overall great. I was forced to check my carry-on backpack from EWR to BOS but it came out on the luggage carousel so fast I didn't even get delayed for my pickup.

Flight attendant walked away once they landed and we were forced to wait another hour after an already 3hr delay.

No overhead space so all carryons were checked. No internet.

The flight was on time and everything went very smoothly.

A thousand choices for movies and nothing to watch. I avoid 'R' rated shows and others with violence and sexual content, which results in a handful of flicks to view and I have them already.

I think I paid for an extra legroom seat and to be honest, there was not a lot of space available for my not very long legs. The flight was totally full and the staff did everything possible to meet the needs of all passengers. My only concern was for the size and spacing of my seat.

Two issues. The plane was old and dirty. The armrest looked like an old car that had the vinyl rubbed off. The Seats in these aircraft are about as hard and uncomfortable. I want to tour Italy for a month and I want to buy a one-way ticket to Thailand but I will not sit in the seats these planes have. It is seriously stupid how hard they are.

The meals were mediocre and the alcohol selection was poor. I enjoyed the selection of movies and other entertainment.

I chatted with the captain before the flight, and similarly during the welcome announcement, he warned of a turbulent flight that may impact the in-flight service. However, once at altitude, he announced that the weather changed and he immediately turned off the seatbelt sign. But it appeared the cabin crew had already decided to take off this flight. They remained seated and then just chatted in the galley. The flight was fully catered, but only first class received service.

they should make XXL people buy two seats. sitting next to a person that was half on my seat and could not even buckle the seat belt, so I had to lean in the isle the whole trip.

The flight left a bit late, but arrived close to time expected…With the flight being close to full the crew did well serving drinks to all in a very timely fashion. The flight was a pleasure…

I thought since I upgraded my seat I would get some perks. Free water, free snacks. Free carry on luggage.

Seats were surprisingly comfortable, and crew was polite. I did not like the baggage fee prices, the minimal amount of flight choices for my area and the difficulty of the self service bag drop.

Lost MacBook, had time to retrieve, but was told I had no time. Need Silver MacBook back

It’s ridiculous to pay for carry-on luggage. I also wasn’t given an option to specify I have carry on bag at time of ticket purchase. I also could not specify I have carry on luggage at time of online check-in.

I’ve now flown Spirit a few times and while the general perception of Spirit I feel is poor, I’ve had a great experience each time. They do charge extra for everything but you should know that going in

The people were wonderful, but I hated the way they over charged for luggage, especially for stops which were charged the same as starting point to final destination.

First time flying Spirit and I was pleasantly surprised. Service was as advertised. Crew were very professional and friendly and excellent in dealing with a customer who felt ill on the flight.

Delayed fight LAS to LAX. OK, fog in LA, not your fault. But all your staff, onboard in in lounge, speak so fast, enunciate so poorly and often have a accent that it is impossible to understanding anything they are saying.

Very mean staff. No entertainment.. No WiFi, a baby cried for over 3 hours no staff offer to assist. My son $500 computer screen got damaged under the plane due to force check in of my bag. TERRIBLE EXPERIENCE!

Nothing I liked. Seats uncomfortable child behind kicking my seat entire flight. Delayed. Couldn't get free glass of water

Book cheap flights from St. Louis to South Carolina

Recent round-trip flight deals

 
These are the cheapest round-trip flights from St. Louis to South Carolina found on KAYAK in the last 72 hours.
1/9Thu
1 stopFrontier
13h 46mSTL-CLT
1/11Sat
1 stopFrontier
13h 41mCLT-STL
$118
1/9Thu
1 stopFrontier
13h 46mSTL-CLT
1/13Mon
1 stopFrontier
8h 34mCLT-STL
$124
1/23Thu
1 stopSpirit Airlines
5h 30mSTL-CHS
1/26Sun
1 stopSpirit Airlines
8h 28mCHS-STL
$185
1/16Thu
1 stopSpirit Airlines
5h 30mSTL-CHS
1/19Sun
1 stopSpirit Airlines
8h 28mCHS-STL
$203
1/17Fri
1 stopDelta
5h 44mSTL-CAE
1/21Tue
1 stopDelta
5h 57mCAE-STL
$248
12/31Tue
1 stopDelta
5h 42mSTL-CAE
1/7Tue
1 stopDelta
5h 57mCAE-STL
$253
1/1Wed
1 stopAmerican Airlines
5h 05mSTL-CAE
1/8Wed
2 stopsAmerican Airlines
7h 13mCAE-STL
$258
1/11Sat
1 stopAmerican Airlines
3h 58mSTL-HHH
1/17Fri
1 stopAmerican Airlines
6h 41mHHH-STL
$258
1/13Mon
2 stopsSouthwest
8h 20mSTL-CHS
1/16Thu
2 stopsSouthwest
9h 05mCHS-STL
$352
1/13Mon
2 stopsSouthwest
10h 55mSTL-CLT
1/20Mon
nonstopSouthwest
2h 05mCLT-STL
$358

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Recent one-way flight deals

 
Only flying one-way? Below are some of the best one-way flight deals from St. Louis to South Carolina found on KAYAK in the last 72 hours.
1/18Sat
1 stopFrontier
13h 50mSTL-CLT
$65
1/24Fri
1 stopFrontier
23h 36mSTL-CLT
$75
1/23Thu
1 stopSpirit Airlines
6h 00mSTL-CLT
$90
1/23Thu
1 stopSpirit Airlines
5h 30mSTL-CHS
$91
12/25Wed
1 stopDelta
5h 19mSTL-GSP
$148
1/14Tue
1 stopDelta
5h 54mSTL-SAV
$151
1/14Tue
nonstopAmerican Airlines
2h 02mSTL-CLT
$160
2/21Fri
1 stopAmerican Airlines
4h 16mSTL-GSP
$163
1/16Thu
nonstopSouthwest
1h 45mSTL-CLT
$172
1/17Fri
2 stopsSouthwest
10h 00mSTL-SAV
$176

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Last minute flights from St. Louis to South Carolina

Last minute flight, train and bus deals

 
These last-minute flight deals are the cheapest flights found on KAYAK in the last 72 hours for flights from St. Louis to South Carolina that are departing in the next 10 days.
12/18Wed
multi-stopFrontier
14h 14mSTL-CLT
12/23Mon
multi-stopFrontier
5h 51mCLT-STL
$408
12/20Fri
multi-stopFrontier
7h 02mSTL-CLT
12/22Sun
multi-stopFrontier
10h 48mCLT-STL
$424
12/20Fri
multi-stopAmerican Airlines
4h 38mSTL-CAE
12/22Sun
multi-stopAmerican Airlines
5h 45mCAE-STL
$479
12/21Sat
multi-stopAmerican Airlines
5h 01mSTL-AGS
12/30Mon
multi-stopAmerican Airlines
4h 50mAGS-STL
$558
12/20Fri
multi-stopDelta
4h 19mSTL-GSP
12/29Sun
multi-stopDelta
4h 23mGSP-STL
$586
12/22Sun
multi-stopDelta
4h 27mSTL-MYR
12/25Wed
multi-stopDelta
4h 27mMYR-STL
$592
12/19Thu
multi-stopSouthwest
4h 35mSTL-GSP
12/23Mon
multi-stopSouthwest
5h 10mGSP-STL
$606
12/19Thu
multi-stopSouthwest
6h 50mSTL-GSP
12/23Mon
multi-stopSouthwest
4h 50mGSP-STL
$611
12/19Thu
multi-stopSpirit Airlines
26h 24mSTL-CHS
12/21Sat
multi-stopSpirit Airlines
19h 35mCHS-STL
$675
12/22Sun
multi-stopSpirit Airlines
30h 46mSTL-MYR
12/25Wed
multi-stopSpirit Airlines
21h 11mMYR-STL
$800

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Everything you need to know for your flight from St. Louis to South Carolina

Information on your arrival and departure airports

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