$62 Find Cheap Flights from St. Louis to South Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from St. Louis to South Carolina departing on 4/2. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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These are the airlines KAYAK users have selected most often from within our search results in flight searches from St. Louis to South Carolina, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from St. Louis to South Carolina, as well as popular online travel agencies
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Best South Carolina Flight Deals from St. Louis

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours

Charleston
Charleston1 stop$123
Myrtle Beach
Myrtle Beach3 stops$283
Greenville
Greenville1 stop$287
Columbia
Columbia1 stop$249

Good to know

Low season

January

High season

June

Cheapest flight

$62
Best time to beat the crowds with an average 6% drop in price.
Most popular time to fly with an average 5% increase in price.
Flight from St. Louis to Charlotte

FAQs - booking South Carolina flights

  • How long is the flight to South Carolina from St. Louis?

    Flights to Myrtle Beach2h 05m
    Flights to Charleston2h 05m
  • What is the cheapest flight to South Carolina from St. Louis?

    The cheapest ticket to South Carolina from St. Louis found in the last 72 hours was $62 one-way, and $120 round-trip. The most popular route is from St. Louis to Charleston, and the cheapest round-trip airline ticket found on this route in the last 72 hours was $78.

  • Which airlines fly to South Carolina?

    Southwest flies most frequently to Charleston from St. Louis.

  • How does KAYAK find such low prices on flights from St. Louis to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from St. Louis to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from St. Louis to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from St. Louis to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from St. Louis to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from St. Louis to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from St. Louis to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from St. Louis to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Top tips for finding cheap flights to South Carolina

  • Looking for a cheap flight? 25% of our users found tickets from St. Louis to the following destinations at these prices or less: Charlotte $181 one-way - $384 round-trip
  • Book at least 1 week before departure in order to get a below-average price.
  • High season is considered to be May, June and July. The cheapest month to fly from St. Louis is October.
  • Morning departure is around 12% more expensive than an evening flight, on average*.
See more tips
*Average of the lowest prices shown in KAYAK’s search results for departures within the next 30 days

Top 5 airlines serving from St. Louis to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from St. Louis to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from St. Louis to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.1
SouthwestOverall score based on 4411 reviews
8.1Comfort
8.7Crew
7.1Food
8.2Boarding
7.6Entertainment
Airline reviews

Gate agents were informative and friendly… flight attendants were as well. Had a fun time chatting about their legacy AirTran experiences as a former fan of the airline that Southwest acquired.

10.0 ExcellentAnonymous, Jan 2025ATL - LGA
Read more Southwest reviews

Gate agents were informative and friendly… flight attendants were as well. Had a fun time chatting about their legacy AirTran experiences as a former fan of the airline that Southwest acquired.

Flight was awfully bumpy and landing was a bit jolting. I was in the restroom when snacks and drinks were served and was not asked if i wanted any. I had to ask for water finally.

Wi Fi was horrible kept cutting out the whole time and too expensive

I really like open seating. I hate that I've heard this is going away. This is one of the unique things that makes Southwest my goto choice.

Boarding was a little late, but made up for it. It was quick to taxi to the runway, since it's a smallish airport.

Excellent! Only question is how we check in at exactly 24 hours in advance and end up at the end of the B boarding group

Multiple delays and gate changes. Arrived at final destination 6 hours late. All rental cars had been taken.

Employees were kind and funny, as always! Flight was late but no announcements were made for people with tight connections to help them transition quickly. No service due to turbulence.

It was 2 hours 45 minutes late, for no apparently clear reason.

I recently flew Southwest from San Jose to Honolulu. I was very impressed with the flight crew, especially the flight attendant in charge of the front of the plane. She came through the aisle at least five times for drinks and water, and two times for snacks. I have not seen such service since I flew first class. Also, for the first time, they gave us the correct baggage claim number, and the luggage came out quickly. I can't wait for Southwest to have assigned seating! I absolutely hate the Cattle Call boarding procedure and the mad dash to get seats and overhead bins. However, the boarding was efficient.

Boarding is, as it always is… horrible. Gate lice. Slow moving zones. Too many people with carry ons

I loved having a most black flight crew during Black History Month; rather by design or accident I appreciated the representation. ❤️

This was the second flight this week with flight attendant Marcus I’m not sure if his last name is Lane or Lang but this guy is awesome. He funny, attentive and his service is 5 stars. Marcus makes business travel more enjoyable !

Although the flight left late, we arrived early. It was one of the quickest boarding and off boarding experiences I’ve had. It was kind of annoying the only drinks they had were water, coffee, and tea. The flight was very smooth, temperature was just right, and flight attendants were friendly.

Lower number on this flight so spaced out passengers. Able to enjoy more room to relax during flight. It was lovely.

Kind staff. Snacks are small but that’s the new normal.

The young man who was our flight attendant in first class was lazy and did not do his job well at all. Never offered drinks upon boarding - actually I take that back... said "are you okay with water" as if I do not want to get you anything else, only passed the snacks around once, got my drink order wrong and then never offered a second round of drinks. He was the worst I have ever seen on Delta and we fly a lot.

Great service. Great staff. Boarding was a little slow, but I think there was a service dog slowing things down.

Flight left early and arrived early. the whole trip was excellent.

Seats were really tight and the seat belts did not give enough slack.

I don’t understand the purpose of the orange “priority” tag on my bag. This tagged, my bag is last or near to the last bag to come down the carousel at IAH.

The tv monitor in front of my seat was not responding. The flight crew reset it and it still didn’t work.

The agents was very rude and they charged me $50 for a carry-on bag saying that it was too big and then I saw someone going on a plane with the same size bag as me

Terrible. First of all we were delayed 4 3/4 hours departing Honolulu. As we had to leave our condo and the rental car had to be returned we had to go to the airport. Even though we had a business class boarding pass to Washington, since we did not have business class to Montreal we could not access the lounge without paying a $59 fee each. This does not make sense to us. Since we could not meet our original connection United booked us to Montreal via New York LaGuardia on Air Canada. In Washington a further delay got us into LaGuardia too late to make our connection to Montreal so we were booked on another Air Canada flight 3 hours later. We were originally scheduled to arrive in Montreal at 10:40 and arrived at 19:55. A totally exhausting day, United did not offer a meal voucher or any type of compensation. Air Canada did give us a digital meal voucher. The food in United business class is poor among all meals offered. The pods look nice but are not that confortable. Overall would not fly on United again.

Plenty of room for me and the cat in Premium Economy. Seat was comfortable. Boarding was a breeze. The lady at the special check-in desk was great, super helpful and professional.

For the most part united was a good experience, how ever when they came by with the snacks and water, they completely passed by my wife and I. As we were in separate rows. On a 5 hr flight we were not offered water

Fantastic crew. Flight was delayed at last minute but we were given updates every 20 minutes and the crew was so friendly and considerate. I miss the touch screens on the back of the seats, wish they would bring that back though.

Our seats were all the way in back of the plane,

Food choices were very limited. Taste of the dishes was average.

Maybe add a seat trade app for flyers that didn’t get seats together

Delays on all NY flights. There was no communication on why but they didn’t say it was weather. Other carriers were not delayed.

The flights were terribly delayed and then cancelled which forced us booking another night at the hotel. Very poor management from American Airlines

Extraordinary service in business class, and very good breakfast and snacks. A really lovely flight.

I flew out of Reagan National. My flight was delayed, delayed, delayed, and then canceled ...THREE TIMES over TWO DAYS. Staff were seemingly not empowered to provide information on why the flights were screwed up. A real nightmare.

They cancelled our flight without warning OR a refund. Never doing business with American Airlines again! This is the second AA booked trip in a row that we've had challenges with.

Crew was late. Baggage was late. 2hs inside the plane waiting fro de-icing and traffic. A 3:30hs flight ended up being almost 6hs inside the airplane.

Flight delayed on both ends - have a gate ready at DCA, don't make us sit for 30min after being late to take off as well.

The seats were crammed and the guy in front of me wouldn't stop reclining. If AA is cramming extra rows in, they need to take away the reclining in coach. My knees were smashed for 4 1/2 hours and I was very close to confronting the passenger in front of me.

This flight didn’t happen because AA agents didn’t let us board the flight

It was so bad it will be my last. Connecting flight gate agent closed the door in my face when i told her my husband is 30 seconds away (and we were running close/late because the preceding AA flight was slightly delayed. We had to be rebooked on a non-direct flight with an overnight layover in Phoenix. This is the worst experience ever and for no fault of our own. The flight we were trying to get on would not have been late if the gate agent allowed my husband to get there. It was senseless, cruel and very upsetting. I don’t understand why we were subjected to this.

Your crew is a representation of your Standards and Values. The crew from Seattle to LAX, was very disappointing. The crew was more interested in hanging out at the lobby area. Talking, laughing loudly and eating all the snacks. They did not do regular rounds to see if customers needed anything. This was a huge disappointment. I will no longer be flying with your airlines moving forward.

The senior flight attendant was engaging, funny and made everyone feel at ease. She is an asset to your team.

Terrible-extreme delay with very little communication, plane was overfull, luggage was returned on baggage claim in filthy condition.

Needs legroom for tall people. Needs to offer a glass of water.

Seats are very uncomfortable pls make your seats comfortable pls pls pls

They changed our departure time 6 times before I even reached the airport. Delayed, Ontime, Delayed Back on time, Then Delayed. We finally boarded the plane and then we had to sit on the runway for over an hour only to be told they were taking us back to the gate for an additional 2 hour delay. Lack of communication and a complete waste of time! Never again!

Non-professional acting crew, Very uncomfortable seats…!! Very bad pricing with all the add-ons for seat choice, luggage fees, etc….soon you’ll charge extra for oxygen. The ticket price means Nothing because in the end, the actual amount i paid, i could have and will in the future continue to fly on a real airline…

I was surprised by a mandatory bag charge when I checked in at the airport. "Carry-on" wasn't an option eventhough all that I had was a small pilot case. I paid $79 so my bag could fly with me.

The flight took an extra 30 min to take off because we were waiting for crew to board then it took another 30 min to get off the plane because there was no parking. Just overall ridiculous also please add a head rest my neck was gonna snap off thanks.

I was traveling with my son and it was our first time with spirit so I didn’t realize our seats weren’t assigned. They scrambled and gave us seats next to each other. Also My son got sick on the plane and they really took care of him. Super family friendly crew and experience!

Book cheap flights from St. Louis to South Carolina

Recent round-trip flight deals

 
These are the cheapest round-trip flights from St. Louis to South Carolina found on KAYAK in the last 72 hours.
5/7Wed
1 stopFrontier
14h 10mSTL-CLT
5/8Thu
1 stopFrontier
26h 30mCLT-STL
$120
4/22Tue
1 stopSpirit Airlines
23h 34mSTL-CHS
4/29Tue
1 stopSpirit Airlines
7h 02mCHS-STL
$123
5/7Wed
1 stopAmerican Airlines
7h 06mSTL-CHS
5/12Mon
1 stopAmerican Airlines
5h 26mCHS-STL
$214
3/12Wed
1 stopAmerican Airlines
4h 41mSTL-CHS
3/15Sat
1 stopAmerican Airlines
4h 53mCHS-STL
$217
3/6Thu
1 stopDelta
8h 08mSTL-CAE
3/10Mon
1 stopDelta
6h 58mCAE-STL
$259
3/25Tue
1 stopDelta
7h 07mSTL-GSP
4/1Tue
1 stopDelta
4h 27mGSP-STL
$287
4/22Tue
1 stopSouthwest
8h 45mSTL-CHS
4/29Tue
nonstopSouthwest
2h 20mCHS-STL
$297
3/19Wed
1 stopSouthwest
5h 25mSTL-CHS
3/26Wed
1 stopSouthwest
5h 40mCHS-STL
$307
3/25Tue
1 stopUnited Airlines
5h 48mSTL-GSP
4/1Tue
2 stopsUnited Airlines
12h 18mGSP-STL
$363
3/12Wed
2 stopsUnited Airlines
9h 51mSTL-GSP
3/19Wed
2 stopsUnited Airlines
9h 23mGSP-STL
$367

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Recent one-way flight deals

 
Only flying one-way? Below are some of the best one-way flight deals from St. Louis to South Carolina found on KAYAK in the last 72 hours.
4/2Wed
1 stopFrontier
16h 03mSTL-CLT
$62
4/1Tue
1 stopFrontier
13h 34mSTL-CLT
$63
4/15Tue
1 stopSpirit Airlines
14h 24mSTL-CLT
$74
3/18Tue
1 stopSpirit Airlines
14h 55mSTL-CHS
$78
3/19Wed
1 stopAmerican Airlines
7h 10mSTL-CHS
$109
3/17Mon
1 stopAmerican Airlines
4h 25mSTL-CHS
$135
3/18Tue
1 stopDelta
10h 15mSTL-CHS
$137
3/17Mon
2 stopsDelta
15h 59mSTL-CHS
$143
5/20Tue
nonstopSouthwest
2h 00mSTL-CHS
$144
5/20Tue
2 stopsSouthwest
11h 25mSTL-CHS
$159

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Last minute flights from St. Louis to South Carolina

Last minute flight, train and bus deals

 
These last-minute flight deals are the cheapest flights found on KAYAK in the last 72 hours for flights from St. Louis to South Carolina that are departing in the next 10 days.
2/22Sat
multi-stopFrontier
12h 48mSTL-CLT
2/24Mon
multi-stopFrontier
16h 35mCLT-STL
$320
2/24Mon
multi-stopFrontier
12h 48mSTL-CLT
3/10Mon
multi-stopFrontier
16h 41mCLT-STL
$343
2/24Mon
multi-stop
32h 35mSTL-CLT
3/10Mon
multi-stop
35h 42mCLT-STL
$353
2/24Mon
multi-stopAmerican Airlines
4h 26mSTL-SAV
2/26Wed
multi-stopAmerican Airlines
6h 46mSAV-STL
$449
2/24Mon
multi-stopAmerican Airlines
6h 56mSTL-SAV
2/28Fri
multi-stopAmerican Airlines
4h 32mSAV-STL
$454
2/23Sun
multi-stopSpirit Airlines
23h 13mSTL-CLT
2/25Tue
multi-stopSpirit Airlines
9h 02mCLT-STL
$541
2/25Tue
multi-stopDelta
6h 33mSTL-GSP
2/28Fri
multi-stopDelta
4h 40mGSP-STL
$551
2/25Tue
multi-stopSouthwest
3h 10mSTL-GSP
2/28Fri
multi-stopSouthwest
10h 55mGSP-STL
$562
2/25Tue
multi-stopSouthwest
9h 30mSTL-GSP
2/28Fri
multi-stopSouthwest
10h 55mGSP-STL
$567
2/21Fri
multi-stopDelta
4h 07mSTL-SAV
2/28Fri
multi-stopDelta
6h 01mSAV-STL
$761

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Everything you need to know for your flight from St. Louis to South Carolina

Information on your arrival and departure airports

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