STL - SAN

$109 Find Cheap Flights from St. Louis to San Diego

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from St. Louis to San Diego departing on 5/4. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult

KAYAK searches hundreds of travel sites at once for deals on flights to San Diego

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from St. Louis to San Diego, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from St. Louis to San Diego, as well as popular online travel agencies
Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 23% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Cheap Flights from St. Louis to San Diego

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from St. Louis to San Diego that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.

Recent round-trip flight deals from St. Louis to San Diego

KAYAK's recommended round-trip deals from the most popular airlines that fly from St. Louis to San Diego.
Discover the best prices for you by selecting your travel dates on KAYAK.
Choose your dates
Frontier Logo
6:58 pm - 12:14 amSTL-SAN
7h 16m1 stop
Frontier Logo
8:50 pm - 10:01 amSAN-STL
11h 11m1 stop
$213Frontier
Find Deal
Wed, Apr 23 - Sun, Apr 27
Frontier Logo
6:58 pm - 12:14 amSTL-SAN
7h 16m1 stop
Frontier Logo
6:25 am - 9:05 pmSAN-STL
12h 40m1 stop
$235Frontier
Find Deal
Mon, Apr 28 - Thu, May 1
United Airlines Logo
8:30 am - 1:57 pmSTL-SAN
7h 27m1 stop
United Airlines Logo
6:30 am - 3:30 pmSAN-STL
7h 00m1 stop
$257United Airlines
Find Deal
Wed, May 21 - Sun, May 25
United Airlines Logo
3:40 pm - 10:29 pmSTL-SAN
8h 49m1 stop
United Airlines Logo
2:27 pm - 11:48 pmSAN-STL
7h 21m2 stops
$262United Airlines
Find Deal
Mon, Apr 28 - Wed, Apr 30
American Airlines Logo
5:26 am - 10:01 amSTL-SAN
6h 35m1 stop
American Airlines Logo
10:33 pm - 9:37 amSAN-STL
9h 04m1 stop
$267American Airlines
Find Deal
Tue, Apr 22 - Sun, Apr 27
Delta Logo
6:00 am - 1:10 pmSTL-SAN
9h 10m1 stop
Delta Logo
11:51 am - 9:36 pmSAN-STL
7h 45m1 stop
$277Delta
Find Deal
Thu, Apr 17 - Sun, Apr 20
Delta Logo
5:00 pm - 10:27 pmSTL-SAN
7h 27m1 stop
Delta Logo
5:02 pm - 12:33 amSAN-STL
5h 31m1 stop
$284Delta
Find Deal
Sat, May 3 - Wed, May 7
American Airlines Logo
7:19 pm - 11:43 pmSTL-SAN
6h 24m1 stop
American Airlines Logo
10:39 pm - 9:49 amSAN-STL
9h 10m1 stop
$292American Airlines
Find Deal
Thu, May 29 - Mon, Jun 2
Southwest Logo
10:55 am - 3:10 pmSTL-SAN
6h 15m2 stops
Southwest Logo
3:00 pm - 10:05 pmSAN-STL
5h 05m1 stop
$308Southwest
Find Deal
Wed, May 28 - Tue, Jun 3
Southwest Logo
2:00 pm - 8:30 pmSTL-SAN
8h 30m2 stops
Southwest Logo
5:00 pm - 12:20 amSAN-STL
5h 20m1 stop
$313Southwest
Find Deal
Sat, Jun 14 - Tue, Jun 17

KAYAK's insights & trends for St. Louis to San Diego flights

Get data-powered insights and trends into flights from St. Louis to San Diego to help you find the cheapest flights, the best time to fly and much more.
Find cheap flights to San Diego
Find cheap flights to San Diego

Planning a trip from St. Louis to San Diego? KAYAK’s data-powered insights will help you find cheap flights. Learn the best time to fly, how early to book your ticket, and other tips to secure great prices.

What’s the cheapest day of the week to fly from St. Louis to San Diego?

The average price of all round-trip flights from St. Louis to San Diego clicked on KAYAK for each day over the last 12 months.
For St. Louis to San Diego, Tuesday is the cheapest day to fly on average and Saturday is the most expensive. Flying from San Diego back to St. Louis, the best deals are generally found on Wednesday, with Sunday being the most expensive.

What is the cheapest month to fly from St. Louis to San Diego?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from St. Louis to San Diego, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.
The cheapest month for flights from St. Louis to San Diego is January, where tickets cost $276 (return) on average. On the other hand, the most expensive months are March and June, where the average cost of round-trip tickets is $454 and $380 respectively.

How far in advance should I book a flight from St. Louis to San Diego?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from St. Louis to San Diego, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.
To get a below average price on the flight from St. Louis to San Diego, you should book around 2 weeks before departure. For the absolute cheapest price, our data suggests you should book 9 weeks before departure.

Good to know

Low season

February

High season

June

Cheapest flight

$109
Best time to beat the crowds with an average 2% drop in price.
Most popular time to fly with an average 12% increase in price.
Flight from St. Louis to San Diego

When to book flights from St. Louis to San Diego

Are your dates flexible? Find out the best times to travel from St. Louis to San Diego based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from St. Louis to San Diego

  • How can I fly from STL to SAN?

    Southwest operates a non-stop flight from STL to SAN. Airlines such as Frontier, United Airlines, Delta, and American Airlines operate one-stop flights from STL to SAN. Some of the layover cities include Dallas (DFW), Denver (DEN), Minneapolis (MSP), Las Vegas (LAS), and Houston (IAH). American Airlines and United Airlines are among the carriers that operate flights from STL to SAN with two layovers.

  • Does STL have nursing rooms?

    Yes. STL has installed Lactation Suites in Gates A10, C9, and E33. Each unit has a comfortable club chair with a full back and a movable arm table, a sink with counter space, and power outlets.

  • Does STL have a USO?

    Yes. There are two USO lounges at STL, one in Terminal 1 at Baggage Claim M6. This lounge is open 24h. The other is in Terminal 2 near Exit 11 by Baggage Claim, open from 7 am until 6 pm. Some amenities in these lounges include showers, a sleeping area with beds, a library, a children's play area, snacks and beverages, computers, Wi-Fi, TV, comfortable seating, and more.

  • How do I get from SAN into downtown San Diego?

    From Lindbergh Field at Terminal 1 at STL, you can catch a San Diego Metro Transit bus #992 into downtown San Diego at Broadway and State Street. This trip takes about 18min and buses depart about every 20min. Taxis and shuttles can get you from STL to downtown San Diego in less than half the time but at about twice the price of a bus.

  • What is the cheapest flight from St. Louis to San Diego?

    In the last 3 days, the lowest price for a flight from St. Louis to San Diego was $109 for a one-way ticket and $213 for a round-trip.

  • Do I need a passport to fly between St. Louis and San Diego?

    A passport is not required to fly from St. Louis to San Diego.

  • Which airlines offer Wi-Fi service onboard planes from St. Louis to San Diego?

    American Airlines, and Alaska Airlines offer inflight Wi-Fi service on the St. Louis to San Diego flight route.

  • Which aircraft models fly most regularly from St. Louis to San Diego?

    The Boeing 737-700 Passenger/BBJ1 (winglets) is the aircraft model that flies most regularly on the St. Louis to San Diego flight route.

  • On which days can I fly direct from St. Louis to San Diego?

    There are nonstop flights from St. Louis to San Diego on a daily basis.

  • Which is the best airline for flights from St. Louis to San Diego, Southwest or Delta?

    The two airlines most popular with KAYAK users for flights from St. Louis to San Diego are Southwest and Delta. With an average price for the route of $493 and an overall rating of 8.0, Southwest is the most popular choice. Delta is also a great choice for the route, with an average price of $285 and an overall rating of 8.0.

  • How does KAYAK find such low prices on flights from St. Louis to San Diego?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from St. Louis to San Diego.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from St. Louis to San Diego?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Diego from St. Louis is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from St. Louis to San Diego?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Diego with an airline and back to St. Louis with another airline. Booking your flights between St. Louis and SAN can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from St. Louis to San Diego?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Diego from St. Louis up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

KAYAK’s top tips for finding a cheap flight from St. Louis to San Diego

  • Looking for a cheap flight? 25% of our users found flights on this route for $204 or less one-way and $487 or less round-trip.
  • The St. Louis Lambert International Airport (STL) is a hub for Cape Air and Air Choice One. San Diego International Airport (SAN) is a focus city for Southwest Airlines and Alaskan.
  • You can park your car at STL long-term before your trip to SAN at B Lot and D Lot. Free shuttles run every 10min between these lots and the terminals. There are garages and surface lots closer to the terminals, within walking distance, but these parking options are more expensive. You can check the STL homepage to see what availability there is in each of the lots.
  • At the Baggage Claim in Terminals 1 and 2 at SAN, passengers can take advantage of Traveler’s Aid if they need to. This non-profit facility is open from 8 am until 11 pm, and it provides aid to travelers who are stranded or distressed. Traveler’s Aid can assist you with issues such as transportation assistance, emergency housing, lost or stolen money, and more.
  • STL has a total of six animal relief areas for travelers who have a pet or service animal with them. The animal relief stations in the terminal can be found at Gates E4, A16, C24, and E40. The relief areas that are outside can be accessed through Exit 6 in Terminal 1 and Exit 15 in Terminal 2.
  • STL has an airport and travel-themed kids' play area, the St Louis International Playport, at Gate 2 on Concourse C. At this indoor playground, kids can play with a kid-sized plane, car, van, and truck. There is also a control tower with a sliding board, a pretend luggage conveyor belt, a pretend security area with a pretend X-ray machine, and a play-car rental counter.
See more tips

Prefer to fly direct from St. Louis to San Diego?

Find which airlines fly direct from Lambert-St Louis Airport to San Diego Airport, which days they fly and book direct flights.

Direct departures

Lambert-St Louis to San Diego

Monday

Southwest

Southwest

Tuesday

Southwest

Southwest

Wednesday

Southwest

Southwest

Thursday

Southwest

Southwest

Friday

Southwest

Southwest

Saturday

Southwest

Southwest

Sunday

Southwest

Southwest

See more direct flights

Direct returns

San Diego to Lambert-St Louis

Monday

Southwest

Southwest

Tuesday

Southwest

Southwest

Wednesday

Southwest

Southwest

Thursday

Southwest

Southwest

Friday

Southwest

Southwest

Saturday

Southwest

Southwest

Sunday

Southwest

Southwest

See more direct flights
See more direct flights

Top 5 airlines serving from St. Louis to San Diego

 
See real verified KAYAK customer reviews for airlines flying from St. Louis to San Diego. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from St. Louis to San Diego? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4275 reviews
7.1Food
8.0Comfort
8.6Crew
8.2Boarding
7.6Entertainment
Airline reviews

Boarding process, crew were good. But the seats were so uncomfortable that was all I could focus on. I literally had to sit forward so that all 3 of us could fit in row. I will try to avoid Southwest in the future for any flights over 60 minutes.

6.0 GoodCarolynn, Mar 2025KOA - SMF
Read more Southwest reviews

Boarding process, crew were good. But the seats were so uncomfortable that was all I could focus on. I literally had to sit forward so that all 3 of us could fit in row. I will try to avoid Southwest in the future for any flights over 60 minutes.

Great flight, 47 passengers on a 180 seat plane. Stewardess was pleasant and cheerful.

Great experience flying Southwest. The crew was really kind and helpful, and very friendly with our toddler.

Very good. Sad to learn Southwest is going start to charge for bags

Plane late from DC to Austin 30 minutes. Crew made up much of the time enroute to San Diego.

Fine, but how to board on SW versus othrr airlines, is just lame. Goood staff though and all was solid otherwise.

Exceptional crew! Friendly and professional. Pleasant attitude and treated everyone with respect.

Was as expected. Crowed planes. Too many carryons delaying takeoff. But the ride only took an hour and saved me a lot of time SFO is a not a great airport.

Was as expected. Crowed planes. Too many carryons delaying takeoff. But the ride only took an hour and saved me a lot of time SFO is a hell hole of an airport. It is the new LaGuardia. Everything Cobbled together. Security gates closed. Terri directional signage

I will be flying again Southwest Airlines. Friendly crew, comfortable and affordable.

Seats are much much more comfortable than United, which is what I usually fly

If I pay extra for "comfort+" I expect leg room where I can stretch my legs. I was seated with an attendant's seat blocking my feet. Knee space was fine but my feet had less room than the non-"comfort+" seats. Also, don't go cheap on food when you have flights of 3+ hours. It's insulting.

Only one side of the heafphone jack work. Crew was friendly and helpful.

Great. Flight departed early and arrived early. Deplaning and baggage claim ww were quick.

They separated our seats and moved us to the back of the plane. Hundreds of dollars and thousands of miles used and this was my platinum member experience.

AC barely worked on a 50 minute flight. It was very warm the whole flight. Flight was very bumpy and hard landing.

Got on the plane and then needed to deboard the plane because they didn’t have any pilots?

The flight was canceled two hours before departure, it took over five hours to rebook us on another flight.

Rough day of travel all the way around. Wrong info given to us multiple times and mistakes in their booking making our trip 10 hours longer than planned. I’m bummed because I fly Delta all the time and love them. Mistakes happen. Just bummed that this was a rare trip our whole family was traveling together.

Meh. A late flight meant I missed my connections, and a 2pm LAX arrival turned into gettin in after midnight.

The gate was too far away for the connecting flight

Generally good. The aisles have gotten narrower which can slow down boarding. Flight crew was great! Healthier complimentary snacks would be appreciated. Due to earthquake in San Francisco we had to circle in air space for a bit but then had a smooth landing. I laud the flight crew for their patience ;)

The agents was very rude and they charged me $50 for a carry-on bag saying that it was too big and then I saw someone going on a plane with the same size bag as me

For the most part united was a good experience, how ever when they came by with the snacks and water, they completely passed by my wife and I. As we were in separate rows. On a 5 hr flight we were not offered water

Fantastic crew. Flight was delayed at last minute but we were given updates every 20 minutes and the crew was so friendly and considerate. I miss the touch screens on the back of the seats, wish they would bring that back though.

Awful. Worst airline I have ever been on. Crew were among the rudest people I have ever dealt with. United staff members were rude and disrespectful. My flight was delayed, causing me to miss a connecting flight. I understand things happen, but when staff start lying about what actually happened, that is when I have an issue. Just be honest, really it isn’t that hard. I’m being very honest with this review and I don’t find this difficult what so ever. In fact, because of United Airlines, my Christmas holiday was off to a really rocky start. As someone who has traveled across the world, it has only been United that I have had a truly awful experience.

Boarding always seems a bit chaotic. Seat spacing could leave more for leg room.

Good flight. On time. Boarding and seating was easy. Crew were really friendly, yet professional. Bathroom (by cockpit) was small but serviceable. Some the seats were showing some notable wear & tear, but were comfy. Very happy UA customer. TY! 🤛🏽💗

We arrived early and finally made it to our gate almost an hour after.

We were delayed 3x and because I didn’t purchase my tickets directly from United Airlines I was told I Have to take care of it myself so I called Underpricer and they helped me but before I changed my flights I took the risk of sticking by what my tickets were and was lucky to have gotten on the original all flight with only 15 mins before take off. not sure if I will do this again

One bottle of water and a package of cookies for comfort plus. We had to literally beg a flight attendant for an extra bottle of water later in the flight due to feeling dehydrated.

Flight boarded from Gate 39 at OGG, the farthest gate in the terminal. There were no Hawaiian themed amenities for the flight. The first class service was mediocre at best; I received not special welcome or recognition as an executive platinum member of American Advantage program. The flight attendants were more concerned with their cell phones than saying "thank you" to the passengers as we disembarked. Fortunately, the flight arrived at LAX a few minutes early.

Two flight changes before the scheduled flight. On the day of the flight, the flight was delayed, which caused the connecting flight to be missed. Then, I was directed to another airport (CUN) and traveled to Tulum. American gave a $12 voucher for lunch. The least expensive item on the menu at a Mexican restaurant was $9.99. Driving to Tulum was a bad auto crash, and traffic was delayed two-plus hours. The bottom line is that we should have been at the hotel at noon, but it ended up at 11:30 PM.

Bigger seats. Board back to front! Disembark front to back!

Extraordinary service in business class, and very good breakfast and snacks. A really lovely flight.

This flight didn’t happen because AA agents didn’t let us board the flight

Miami lounges were overcrowded and we were unable to get in. We only had a short time. But the banks are too tight in all American hubs

Plane was pretty clean, staff was friendly and helpful, flight left about on time arrived early. Took a long time to board and get off the plane - carry on items didn't have enough room so people had to move all around to find places.

The service and food needs to improve to catch up with other international flights

Would have been good to have a meal since it was a 5.5 hour flight

Cancelled and declined to find alternatives Earlier flight is 2 days later Sent the cancellation notification very late, wish I knew earlier would have stayed to watch the Miami open final game Very disappointing service

The worst flight of my life. Never will I fly frontier again

Landing in terminal 2, but my luggage is terminal 3. We (and others) were looking for it in terminal 1. We probably missed the crew broadcast, but the communication could have been clearer for non native (or elderly) passengers.

I chose the seats when booked the flight and paid for them. However after checking in I found we were assigned different seats!

Bag should not be so much money. This is how Frontier takes advantage of customers

The plane was comfortable. The time to board was way too slow and very unorganized! The crew was not as friendly as normally. The was not a single time that they offered water nor anything!!!

They switched my flight to Spirit, Never using Kayak again,

i was denied boarding, even though i had an assigned seat, checked in on line and was at airport early. Then they refused to fully refund the the fair and replacement fair because they claimed it was "no show/denied boarding". I will never fly this airline again

I was not permitted on my flight and had to purchase another flight ticket to Las Vegas.

This was a full flight and I was in Zone 1, however upon boarding, several other zones went in ahead of me, leaving no overhead cabin space near my seat. This created a challenging disembarkment process.

Everything you need to know for your flight from St. Louis to San Diego

Information on your arrival and departure airports

Not what you’re looking for? Find thousands of other hotels, flights, car rentals and package deals with KAYAK.