TYS - SAN

$114 Find Cheap Flights from Knoxville to San Diego

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Knoxville to San Diego departing on 5/12. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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KAYAK searches hundreds of travel sites at once for deals on flights to San Diego

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to San Diego, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to San Diego, as well as popular online travel agencies
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Cheap Flight Deals from Knoxville to San Diego (TYS-SAN)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Knoxville to San Diego that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.

Recent round-trip flight deals from Knoxville to San Diego

KAYAK's recommended round-trip deals from the most popular airlines that fly from Knoxville to San Diego.
Discover the best prices for you by selecting your travel dates on KAYAK.
Choose your dates
United Airlines Logo
9:00 am - 1:50 pmTYS-SAN
7h 50m1 stop
United Airlines Logo
6:15 am - 5:56 pmSAN-TYS
8h 41m1 stop
$229United Airlines
Find Deal
Tue, Apr 29 - Tue, May 6
United Airlines Logo
7:00 am - 11:42 amTYS-SAN
7h 42m1 stop
United Airlines Logo
7:10 am - 8:06 pmSAN-TYS
9h 56m2 stops
$234United Airlines
Find Deal
Tue, Apr 29 - Tue, May 6
 Logo
12:50 pm - 7:34 amTYS-SAN
21h 44m1 stop
 Logo
6:15 am - 9:59 pmSAN-TYS
12h 44m1 stop
Mon, Apr 14 - Fri, Apr 18
 Logo
12:50 pm - 7:34 amTYS-SAN
21h 44m1 stop
 Logo
6:15 am - 9:59 pmSAN-TYS
12h 44m1 stop
Mon, Apr 14 - Fri, Apr 18
American Airlines Logo
5:24 am - 10:01 amTYS-SAN
7h 37m1 stop
American Airlines Logo
7:12 am - 5:28 pmSAN-TYS
7h 16m1 stop
$259American Airlines
Find Deal
Wed, Apr 30 - Sun, May 4
American Airlines Logo
6:28 pm - 11:43 pmTYS-SAN
8h 15m1 stop
American Airlines Logo
7:29 am - 5:31 pmSAN-TYS
7h 02m1 stop
$284American Airlines
Find Deal
Tue, May 27 - Tue, Jun 3
Delta Logo
7:10 pm - 11:42 pmTYS-SAN
7h 32m1 stop
Delta Logo
10:00 pm - 10:23 amSAN-TYS
9h 23m1 stop
$293Delta
Find Deal
Fri, May 23 - Sun, May 25
Alaska Airlines Logo
5:15 am - 4:30 pmTYS-SAN
14h 15m2 stops
Alaska Airlines Logo
7:45 pm - 10:07 pmSAN-TYS
23h 22m2 stops
$329Alaska Airlines
Find Deal
Tue, Apr 29 - Tue, May 6
Delta Logo
5:30 am - 10:07 amTYS-SAN
7h 37m1 stop
Delta Logo
10:30 pm - 9:40 amSAN-TYS
8h 10m1 stop
$334Delta
Find Deal
Sun, May 4 - Sun, May 11
Alaska Airlines Logo
6:22 pm - 10:27 pmTYS-SAN
7h 05m1 stop
Alaska Airlines Logo
6:15 am - 9:52 pmSAN-TYS
12h 37m2 stops
$469Alaska Airlines
Find Deal
Fri, Jul 18 - Sat, Aug 2

KAYAK's insights & trends for Knoxville to San Diego flights

Get data-powered insights and trends into flights from Knoxville to San Diego to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Knoxville to San Diego?

The average price of all round-trip flights from Knoxville to San Diego clicked on KAYAK for each day over the last 12 months.
If you are looking for a flight deal from Knoxville to San Diego, look for departures on Wednesdays and avoid leaving on a Sunday, as it's usually the priciest day. When flying back from San Diego, Wednesday is the cheapest day to fly and Sunday is the most expensive.

What is the cheapest month to fly from Knoxville to San Diego?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Knoxville to San Diego, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.
The cheapest month for flights from Knoxville to San Diego is January, where tickets cost $288 (return) on average. On the other hand, the most expensive months are April and March, where the average cost of round-trip tickets is $487 and $468 respectively.

How far in advance should I book a flight from Knoxville to San Diego?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Knoxville to San Diego, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.
To get a below average price on the flight from Knoxville to San Diego, you should book around 2 weeks before departure. For the absolute cheapest price, our data suggests you should book 5 weeks before departure.

Good to know

Low season

February

High season

July

Cheapest flight

$114
Best time to beat the crowds with an average 22% drop in price.
Most popular time to fly with an average 3% increase in price.
Flight from Knoxville to San Diego

When to book flights from Knoxville to San Diego

Are your dates flexible? Find out the best times to travel from Knoxville to San Diego based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Knoxville to San Diego

  • What is the cheapest flight from Knoxville to San Diego?

    In the last 3 days, the lowest price for a flight from Knoxville to San Diego was $114 for a one-way ticket and $229 for a round-trip.

  • Do I need a passport to fly between Knoxville and San Diego?

    Even though you are not required to have a passport, keep in mind that an official ID is needed to board the airplane.

  • Which aircraft models fly most regularly from Knoxville to San Diego?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Knoxville to San Diego?

    oneworld, Star Alliance, and SkyTeam are the airline alliances operating flights between Knoxville and San Diego, with oneworld being the most commonly used for this route.

  • Which is the best airline for flights from Knoxville to San Diego, Delta or Alaska Airlines?

    The two airlines most popular with KAYAK users for flights from Knoxville to San Diego are Delta and Alaska Airlines. With an average price for the route of $392 and an overall rating of 8.0, Delta is the most popular choice. Alaska Airlines is also a great choice for the route, with an average price of $567 and an overall rating of 8.0.

  • How does KAYAK find such low prices on flights from Knoxville to San Diego?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Knoxville to San Diego.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Knoxville to San Diego?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Diego from Knoxville is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Knoxville to San Diego?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Diego with an airline and back to Knoxville with another airline. Booking your flights between Knoxville and SAN can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Knoxville to San Diego?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Diego from Knoxville up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Top 5 airlines serving from Knoxville to San Diego

 
See real verified KAYAK customer reviews for airlines flying from Knoxville to San Diego. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Knoxville to San Diego? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
Alaska AirlinesOverall score based on 9820 reviews
7.1Entertainment
7.9Comfort
7.1Food
8.5Crew
8.2Boarding
Airline reviews

The flight was canceled and very little help given at the check in desk. Everyone at the desk says: just go on the app and see how they rebooked you. I mean come on it’s embarrassing customer service.

2.0 MediocreAnonymous, Mar 2025JAC - SAN
Read more Alaska Airlines reviews

The flight was canceled and very little help given at the check in desk. Everyone at the desk says: just go on the app and see how they rebooked you. I mean come on it’s embarrassing customer service.

The registration was chaotic. The kiosks didn't work for most people, and most had to do registration and receive boarding slips with a person. It took about an hour to get through he process, and I was worrying that I will be late to the flight. However, the personnel was great - courteous, professional, and was able to work through the problems.

I upgraded my seat and the service and boarding were wonderful. My flight attendant was very helpful when I experienced nausea on the flight (a first time experience). Flight arrived early which was nice. The only negative was many airlines have screens to provide some on flight entertainment, this aircraft did not. I had planned to read and listen to an audiobook on my flights, so no big deal on my part. The USB plug ins were broken on both my seat and the center seat, so I was not able to charge my phone during the flight, I will add 2 of the three USBs were broken on ride from San Diego as well. I would attribute this to the design, it is a very awkward angle to plug in, so frequent and perhaps not so gentle attempts to plug in have caused them to break.

Stay with what you are doing. Excellent service and ahead of schedule. Well done.

We had to cancel and we’re treated fairly with 100%refund quickly

There was an issue with water that led to us not having potable water onboard. They dumped the onboard water and we were two hours late taking off.

All good. Great food and entertainment when there isn’t any on a one hour flight

The flight from San Diego to San Jose gate 28A The two persons working there didn’t even turn on the display board. The display board saying to Sacramento. When I asked she was rude and showed the board . Then he realized And changed. Every one was confused because we are running late to catch that flight coming from IAD. Very irresponsible staff.

Great crew, great boarding, old B-list movies, no free meal service, child kicking my seat back all flight long, early arrival, then 40 minute, confused wait for bags.

I liked the flight attendant named Tyler. He was charismatic and genuine. I like the pilot in my second flight, he was considerate to everyone’s feelings. I liked the people I sat beside. I like the plane size. I like Alaska airlines

Seats are much much more comfortable than United, which is what I usually fly

If I pay extra for "comfort+" I expect leg room where I can stretch my legs. I was seated with an attendant's seat blocking my feet. Knee space was fine but my feet had less room than the non-"comfort+" seats. Also, don't go cheap on food when you have flights of 3+ hours. It's insulting.

Only one side of the heafphone jack work. Crew was friendly and helpful.

Great. Flight departed early and arrived early. Deplaning and baggage claim ww were quick.

They separated our seats and moved us to the back of the plane. Hundreds of dollars and thousands of miles used and this was my platinum member experience.

AC barely worked on a 50 minute flight. It was very warm the whole flight. Flight was very bumpy and hard landing.

Got on the plane and then needed to deboard the plane because they didn’t have any pilots?

The flight was canceled two hours before departure, it took over five hours to rebook us on another flight.

Rough day of travel all the way around. Wrong info given to us multiple times and mistakes in their booking making our trip 10 hours longer than planned. I’m bummed because I fly Delta all the time and love them. Mistakes happen. Just bummed that this was a rare trip our whole family was traveling together.

Meh. A late flight meant I missed my connections, and a 2pm LAX arrival turned into gettin in after midnight.

The gate was too far away for the connecting flight

Generally good. The aisles have gotten narrower which can slow down boarding. Flight crew was great! Healthier complimentary snacks would be appreciated. Due to earthquake in San Francisco we had to circle in air space for a bit but then had a smooth landing. I laud the flight crew for their patience ;)

The agents was very rude and they charged me $50 for a carry-on bag saying that it was too big and then I saw someone going on a plane with the same size bag as me

For the most part united was a good experience, how ever when they came by with the snacks and water, they completely passed by my wife and I. As we were in separate rows. On a 5 hr flight we were not offered water

Fantastic crew. Flight was delayed at last minute but we were given updates every 20 minutes and the crew was so friendly and considerate. I miss the touch screens on the back of the seats, wish they would bring that back though.

Awful. Worst airline I have ever been on. Crew were among the rudest people I have ever dealt with. United staff members were rude and disrespectful. My flight was delayed, causing me to miss a connecting flight. I understand things happen, but when staff start lying about what actually happened, that is when I have an issue. Just be honest, really it isn’t that hard. I’m being very honest with this review and I don’t find this difficult what so ever. In fact, because of United Airlines, my Christmas holiday was off to a really rocky start. As someone who has traveled across the world, it has only been United that I have had a truly awful experience.

Boarding always seems a bit chaotic. Seat spacing could leave more for leg room.

Good flight. On time. Boarding and seating was easy. Crew were really friendly, yet professional. Bathroom (by cockpit) was small but serviceable. Some the seats were showing some notable wear & tear, but were comfy. Very happy UA customer. TY! 🤛🏽💗

We arrived early and finally made it to our gate almost an hour after.

We were delayed 3x and because I didn’t purchase my tickets directly from United Airlines I was told I Have to take care of it myself so I called Underpricer and they helped me but before I changed my flights I took the risk of sticking by what my tickets were and was lucky to have gotten on the original all flight with only 15 mins before take off. not sure if I will do this again

One bottle of water and a package of cookies for comfort plus. We had to literally beg a flight attendant for an extra bottle of water later in the flight due to feeling dehydrated.

Flight boarded from Gate 39 at OGG, the farthest gate in the terminal. There were no Hawaiian themed amenities for the flight. The first class service was mediocre at best; I received not special welcome or recognition as an executive platinum member of American Advantage program. The flight attendants were more concerned with their cell phones than saying "thank you" to the passengers as we disembarked. Fortunately, the flight arrived at LAX a few minutes early.

I didn’t like anything, being platinum pro get you absolutely nowhere and does not increase the customer service treatment whatsoever anymore. My flight was canceled and they put me on a flight eight hours later that would’ve got me back in the middle of the night. They could’ve easily move me up to an hour Prior on an earlier flight. My second flight was unreasonable to take, the third flight was also canceled due to mechanical issues like the first flight. I don’t know what’s going on with American, but they are falling apart, after seven flight changes I finally got home, Unreasonable.

Bigger seats. Board back to front! Disembark front to back!

Extraordinary service in business class, and very good breakfast and snacks. A really lovely flight.

This flight didn’t happen because AA agents didn’t let us board the flight

Plane was pretty clean, staff was friendly and helpful, flight left about on time arrived early. Took a long time to board and get off the plane - carry on items didn't have enough room so people had to move all around to find places.

The service and food needs to improve to catch up with other international flights

Would have been good to have a meal since it was a 5.5 hour flight

We boarded after several delays due to mechanical failure and a gate change. The seat cushion in the exit row was very compressed and offered no cushion, making the four-hour journey reasonably uncomfortable. The WiFi worked for a few people, but for most, it did not, and you cannot get entertainment unless you can connect—American Airlines flights do not have seatback screens, and you must use your mobile phone.

Cancelled and declined to find alternatives Earlier flight is 2 days later Sent the cancellation notification very late, wish I knew earlier would have stayed to watch the Miami open final game Very disappointing service

The worst flight of my life. Never will I fly frontier again

Landing in terminal 2, but my luggage is terminal 3. We (and others) were looking for it in terminal 1. We probably missed the crew broadcast, but the communication could have been clearer for non native (or elderly) passengers.

I chose the seats when booked the flight and paid for them. However after checking in I found we were assigned different seats!

Bag should not be so much money. This is how Frontier takes advantage of customers

The plane was comfortable. The time to board was way too slow and very unorganized! The crew was not as friendly as normally. The was not a single time that they offered water nor anything!!!

They switched my flight to Spirit, Never using Kayak again,

i was denied boarding, even though i had an assigned seat, checked in on line and was at airport early. Then they refused to fully refund the the fair and replacement fair because they claimed it was "no show/denied boarding". I will never fly this airline again

I was not permitted on my flight and had to purchase another flight ticket to Las Vegas.

This was a full flight and I was in Zone 1, however upon boarding, several other zones went in ahead of me, leaving no overhead cabin space near my seat. This created a challenging disembarkment process.

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