$123 Find Cheap Flights from Knoxville to Missouri

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Knoxville to Missouri departing on 5/10. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult

KAYAK searches hundreds of travel sites at once for deals on flights to Missouri

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Missouri, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Missouri, as well as popular online travel agencies
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Best Missouri Flight Deals from Knoxville

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours

St. Louis
St. Louis1 stop$214
Kansas City
Kansas City1 stop$199
Springfield
Springfield1 stop$249
Joplin
Joplin1 stop$496

Cheap Flights from Knoxville to Missouri

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Knoxville to Missouri that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.

Recent round-trip flight deals from Knoxville to Missouri

Recommended round-trip deals departing in the coming months from the most popular airlines that fly from Knoxville to Missouri.
Discover the best prices for you by selecting your travel dates on KAYAK.
Choose your dates
American Airlines Logo
8:27 pm - 11:59 pmTYS-MCI
4h 32m1 stop
American Airlines Logo
4:06 pm - 10:07 pmMCI-TYS
5h 01m1 stop
$199American Airlines
Find Deal
Sat, May 24 - Sat, May 31
Delta Logo
5:45 am - 9:00 amTYS-STL
4h 15m1 stop
Delta Logo
5:40 pm - 11:51 pmSTL-TYS
5h 11m1 stop
$214Delta
Find Deal
Wed, May 21 - Wed, May 28
Frontier Logo
5:30 pm - 9:09 amTYS-STL
16h 39m1 stop
Frontier Logo
7:55 pm - 4:29 pmSTL-TYS
19h 34m1 stop
$218Frontier
Find Deal
Thu, May 29 - Sat, May 31
Delta Logo
5:45 am - 8:23 amTYS-STL
3h 38m1 stop
Delta Logo
5:23 pm - 11:59 pmSTL-TYS
5h 36m1 stop
$229Delta
Find Deal
Tue, Jun 10 - Sat, Jun 14
American Airlines Logo
6:10 am - 10:43 amTYS-STL
5h 33m1 stop
American Airlines Logo
5:19 am - 11:41 amSTL-TYS
5h 22m1 stop
$234American Airlines
Find Deal
Mon, May 26 - Sat, May 31
Delta Logo
7:25 pm - 10:30 pmTYS-SGF
4h 05m1 stop
Delta Logo
6:45 pm - 11:47 pmSGF-TYS
4h 02m1 stop
$249Delta
Find Deal
Thu, Aug 21 - Sun, Aug 24
Allegiant Air Logo
10:00 am - 3:18 pmTYS-SGF
6h 18m1 stop
Allegiant Air Logo
9:07 am - 6:12 pmSGF-TYS
8h 05m1 stop
$266Allegiant Air
Find Deal
Sun, May 18 - Mon, May 19
Allegiant Air Logo
8:30 am - 8:27 pmTYS-MCI
12h 57m1 stop
Allegiant Air Logo
9:17 pm - 11:33 pmMCI-TYS
25h 16m2 stops
$278Allegiant Air
Find Deal
Sat, May 24 - Sat, May 31
United Airlines Logo
7:00 am - 12:19 pmTYS-STL
6h 19m1 stop
United Airlines Logo
5:00 am - 10:07 amSTL-TYS
4h 07m1 stop
$289United Airlines
Find Deal
Tue, May 20 - Tue, May 27
United Airlines Logo
7:00 am - 10:29 amTYS-MCI
4h 29m1 stop
United Airlines Logo
7:30 am - 8:56 pmMCI-TYS
12h 26m2 stops
$324United Airlines
Find Deal
Sat, Aug 2 - Wed, Aug 20

KAYAK's insights & trends for Knoxville to Missouri flights

Get data-powered insights and trends into flights from Knoxville to Missouri to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest time of day to fly to Missouri?

The average price for all round-trip flights from Knoxville to Missouri depending on the time of departure, clicked by users on KAYAK in the last 2 weeks.
The cheapest time of day to fly to Missouri is generally in the afternoon, when round-trip flights cost $265 on average. Morning departures are around 8% more expensive than evening flights, on average. The most expensive time of day to fly to Missouri is generally in the morning, which is peak travel time and where the average cost of a ticket is $288.

What is the cheapest month to fly from Knoxville to Missouri?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Knoxville to Missouri, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.
The cheapest month for flights from Knoxville to Missouri is June, when tickets cost $265 (return) on average. On the other hand, the most expensive months are March and January, when the average cost of round-trip tickets is $542 and $323 respectively.

What’s the cheapest day of the week to fly from Knoxville to Missouri?

The average price of all round-trip flights from Knoxville to Missouri clicked on KAYAK for each day over the last 12 months.
If you are looking for a flight deal from Knoxville to Missouri, look for departures on Wednesdays and avoid leaving on a Monday, as it's usually the priciest day. When flying back from Missouri, Thursday is the cheapest day to fly and Sunday is the most expensive.

Good to know

Low season

February

High season

September

Cheapest flight

$123
Best time to beat the crowds with an average 3% drop in price.
Most popular time to fly and prices are also 14% lower on average.
Flight from Knoxville to Springfield

FAQs - booking Missouri flights

  • How does KAYAK find such low prices on flights from Knoxville to Missouri?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Knoxville to Missouri.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Knoxville to Missouri?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Knoxville to Missouri is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Knoxville to Missouri?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Knoxville to Missouri with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Knoxville to Missouri?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Knoxville to Missouri up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Top 3 airlines serving from Knoxville to Missouri

 
See real verified KAYAK customer reviews for airlines flying from Knoxville to Missouri. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Knoxville to Missouri? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
DeltaOverall score based on 7920 reviews
8.5Crew
7.9Comfort
8.2Boarding
7.3Food
7.9Entertainment
Airline reviews

This had nothing to do with Delta… The flights were on time and flawless. The service was excellent. We purchased seats in (aisle/middle) comfort plus since this was a cross country flight. Unfortunately, the woman seated at the window was 300+ pounds and, as might be expected, covered up about a third of the middle seat also. there was absolutely nothing that Delta could have done about that… I just don’t know what the answer should be. If you purchase a seat, you should should be able to use the entire seat and not just the portion that someone else is not sitting/oozing in. Disappointing…there should be something that could be done….I'm just not sure what solution could be.

10.0 ExcellentGary, Apr 2025TPA - LAX
Read more Delta reviews

This had nothing to do with Delta… The flights were on time and flawless. The service was excellent. We purchased seats in (aisle/middle) comfort plus since this was a cross country flight. Unfortunately, the woman seated at the window was 300+ pounds and, as might be expected, covered up about a third of the middle seat also. there was absolutely nothing that Delta could have done about that… I just don’t know what the answer should be. If you purchase a seat, you should should be able to use the entire seat and not just the portion that someone else is not sitting/oozing in. Disappointing…there should be something that could be done….I'm just not sure what solution could be.

Delayed take-off. Very small plane so very scary with lots of bumps during the flight. Would never fly Delta on short flights in small 80 seaters plane again! Felt relieved when landed.

The worst part was I was NOT allowed in the lounge even though I was holding a first class ticket and have a premium American Express card. I have flown Business or First Class with many airlines. Delta is the ONLY one who does not extend this courtesy to anyone except people who hold the very expensive American Express card. As a result, I won’t fly Delta if I have any other choice.

A little bumpy ride . No food was being provided due the the turbulence. That was ok it was a short flight to my standards.

Simply outstanding. Their new lounge for Delta One customers is a cut above the rest.

The Dekta Rep that checked us in was great. She's very personable, pleasant, and can tell she enjoys her job.

The plane was old with small storage areas that had problems closing/latching and not enough storage for everyone, and worn, damaged seats. Service was great but feel a little unsafe on such well used planes.

Terrible and im avoiding them in the future. My initial flight was delayed causing me to rebook my flight and when speaking with the representative to rebook I explained this is the second time my flights were delayed and they did nothing to help me. I wasn't booked to comfort plus or given a voucher or anything. I was almost late for my meeting that I needed to attend on Monday because of the games delta played delaying my flights even more and putting me in the very back of the plane next to an extremely intoxicated passenger

Flights on time. .Ride was as comfortable as can be expected in steerage. Luggage arrived at destination. Attendants were fairly friendly.

Great staff. Wifi is terrible. Signing up for skylines is a painstaking process. Had to call customer service just to get my flight itinerary and confirmation sent to me. Consistent delays. A well staffed company that is run so poorly. Upper management needs to be renewed.

Multiple delays and not straight answer from the United team

Stewardess spilled orange juice on my clothes/seat no help no apology just threw napkins at me to clean the mess up. Not Happy.

Smooth flight. Boarding was chaotic. Could not hear the gate agent over the intercom. People were lined up in the wrong lines. Groups one and two were told to board through line one and group 3 through line 2. All very confusing. Once in the air, the flight was smooth. There was no entertainment option on this aircraft, even though it was a larger aircraft.

The plane pushed back from the gate on time. However, it stopped on the ramp, and we waited for over 20 minutes before the aircraft pulled back to the gate. Apparently, something of importance had to be removed from the aircraft by the gate agent. I found this to be odd. The delay was not significant, but I felt that whatever was on the aircraft that had to be taken off, should’ve been done before we pushed back from the gate.

Electric plugs didn't work. Entertainment system wasn't working

The design of the light switch on the arm rest is ridiculous.

Smooth boarding process. Early departure, smooth flight, early arrival. The entertainment package has very good recent movie options. The flight crew were friendly and professional.

leg space better than expected. two washrooms for one plane isn't enough.

The gate attendant let me walk right by her with a bag too big for the overhead compartment

I just got back from a trip with 3 flights each way. The flights were good and we were happy with out experience. There was one steward on our first flight that was harsh and grump with passengers. It did not leave a good impression. All of the other flight crews were great on the other five flights.

We missed our flight. The boarding pass had the wrong gate and by the time we received the text from Kayak, our flight was already gone. I’ll never use Kayak again and will go direct to the airlines in the future.

Boarding took forever, the plane was cramped and cold, and the seatbelt song came on constantly throughout the red eye flight with a loud pre-recorded message playing each time

Cabin felt crammed Snacks are lame But crew was super efficient getting us out on time despite delay

Took off on time and successfully avoided weather that looked to be a problem along the way

There were five broken seats on the plane. The crew was very rude in telling people they had to get off the plane and get a flight the next day. No call for volunteers, but telling people they had to get off. One woman was flying with her elderly mother and daughter and was told she had to leave or all three had to leave. Fortunately, a volunteer offered to stay. The situation was handled poorly.

The flight to Tokyo AA61 took off about two hours late, but then had to turn back. By that time the crew had to be replaced. Then they kept promising to take off in an hour, then in 3, then switch to the next day.

Any sort of gluten free snack option would be nice

They lost my luggage and it didn’t get delivered until the next day.

Would have thought that they would gas up plane before everyone got on board

3 hours late. Not even water offered on a 2.25 hour flight.

Everything you need to know for your flight from Knoxville to Missouri

Information on your arrival and departure airports

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