$51 Find Cheap Flights from Indianapolis to South Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Indianapolis to South Carolina departing on 5/8. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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These are the airlines KAYAK users have selected most often from within our search results in flight searches from Indianapolis to South Carolina, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Indianapolis to South Carolina, as well as popular online travel agencies
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Best South Carolina Flight Deals from Indianapolis

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours

Charleston
Charleston1 stop$106
Myrtle Beach
Myrtle Beachnonstop$130
Greenville
Greenville1 stop$247
Columbia
Columbia1 stop$229

Good to know

Low season

January

High season

June

Cheapest flight

$51
Best time to beat the crowds but there is an average 14% increase in price.
Most popular time to fly and prices are also 7% lower on average.
Flight from Indianapolis to Charlotte

FAQs - booking South Carolina flights

  • How long is the flight to South Carolina from Indianapolis?

    Flights to Myrtle Beach1h 42m
    Flights to Charleston1h 51m
  • What is the cheapest flight to South Carolina from Indianapolis?

    The cheapest ticket to South Carolina from Indianapolis found in the last 72 hours was $51 one-way, and $99 round-trip. The most popular route is from Indianapolis to Charleston, and the cheapest round-trip airline ticket found on this route in the last 72 hours was $56.

  • How does KAYAK find such low prices on flights from Indianapolis to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Indianapolis to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Indianapolis to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Indianapolis to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Indianapolis to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Indianapolis to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Indianapolis to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Indianapolis to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Top tips for finding cheap flights to South Carolina

  • Looking for a cheap flight? 25% of our users found tickets from Indianapolis to the following destinations at these prices or less: Charlotte $189 one-way - $362 round-trip
  • Book at least 1 week before departure in order to get a below-average price.
  • High season is considered to be January, February and December. The cheapest month to fly from Indianapolis is January.
  • Morning departure is around 14% more expensive than an evening flight, on average*.
See more tips
*Average of the lowest prices shown in KAYAK’s search results for departures within the next 30 days

Top 5 airlines serving from Indianapolis to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Indianapolis to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Indianapolis to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.1
SouthwestOverall score based on 4482 reviews
7.6Entertainment
8.2Boarding
8.7Crew
8.1Comfort
7.1Food
Airline reviews

Gate agents were informative and friendly… flight attendants were as well. Had a fun time chatting about their legacy AirTran experiences as a former fan of the airline that Southwest acquired.

10.0 ExcellentAnonymous, Jan 2025ATL - LGA
Read more Southwest reviews

Gate agents were informative and friendly… flight attendants were as well. Had a fun time chatting about their legacy AirTran experiences as a former fan of the airline that Southwest acquired.

Flight was awfully bumpy and landing was a bit jolting. I was in the restroom when snacks and drinks were served and was not asked if i wanted any. I had to ask for water finally.

Wi Fi was horrible kept cutting out the whole time and too expensive

I really like open seating. I hate that I've heard this is going away. This is one of the unique things that makes Southwest my goto choice.

Boarding was a little late, but made up for it. It was quick to taxi to the runway, since it's a smallish airport.

Excellent! Only question is how we check in at exactly 24 hours in advance and end up at the end of the B boarding group

Multiple delays and gate changes. Arrived at final destination 6 hours late. All rental cars had been taken.

Employees were kind and funny, as always! Flight was late but no announcements were made for people with tight connections to help them transition quickly. No service due to turbulence.

It was 2 hours 45 minutes late, for no apparently clear reason.

I recently flew Southwest from San Jose to Honolulu. I was very impressed with the flight crew, especially the flight attendant in charge of the front of the plane. She came through the aisle at least five times for drinks and water, and two times for snacks. I have not seen such service since I flew first class. Also, for the first time, they gave us the correct baggage claim number, and the luggage came out quickly. I can't wait for Southwest to have assigned seating! I absolutely hate the Cattle Call boarding procedure and the mad dash to get seats and overhead bins. However, the boarding was efficient.

Although the flight left late, we arrived early. It was one of the quickest boarding and off boarding experiences I’ve had. It was kind of annoying the only drinks they had were water, coffee, and tea. The flight was very smooth, temperature was just right, and flight attendants were friendly.

Lower number on this flight so spaced out passengers. Able to enjoy more room to relax during flight. It was lovely.

Kind staff. Snacks are small but that’s the new normal.

The young man who was our flight attendant in first class was lazy and did not do his job well at all. Never offered drinks upon boarding - actually I take that back... said "are you okay with water" as if I do not want to get you anything else, only passed the snacks around once, got my drink order wrong and then never offered a second round of drinks. He was the worst I have ever seen on Delta and we fly a lot.

Great service. Great staff. Boarding was a little slow, but I think there was a service dog slowing things down.

Flight left early and arrived early. the whole trip was excellent.

Seats were really tight and the seat belts did not give enough slack.

I like in St George and prefer to fly out of CDC than SGU. Hopefully, they will continue the flights out of Cedar

Broken jer bridge. Poor communication about it. Lost 2 of 4 luggage pieces

Overall, it was okay. Seat was a little cramped. Would’ve liked more substantial snacks or opportunity to buy some.

Terrible. Still have not received the refund from them. They sent it to some account that I don't even know. Spoke with costumer service and they are unable to help.

I didn’t like it at all. I miss my second flight because of the delay on Allegiant Air now I m stuck in MCO.

Good, but a bit late on take off after loading. Don't like charging for carry ons!

First time flying with them and will definitely fly again in the future. Crew was so nice and friendly, fought was seamless. They are simple planes, no entertainment, but it’s fine for a short flight or if you have personal devices Rates are competitive, and they did so well with keeping the flight on time after a tropical storm, where other airlines had delays and cancellations.

They boarded passengers that sat in the back of the plane first, making boarding very efficient.

I didn't even take this flight. My plans changed and I couldn't get ahold of customer service and the website kept breaking down during the attempt to change the flight. I wound up taking another airline entirely and eating the cost.

The worst flying experience ever 3 delays. No accommodations. Had to deboard the plane after being delayed.

Posted a 20minute delay but didn’t delay at all. Caused boarding issues and confusion. Also, didn’t release baggage. Took over an hour and 20 minutes to get luggage.

Flight was good, boarding was a breeze, flight attendants were friendly and professional. There was a medical issue with another passenger and the crew handled it in a calm and professional way.

The net issue I had was with the gate agent. We had added a carryon to our boarding pass when we checked bags. When I got to the boarding gate the agent was rude asking why I had a backpack - I said I added it - even had an orange tag on it. She ripped my tag off and swung her monitor around to show me how she was right- saying it isn’t wasn’t listed - only a checked bag. I explained again that I wasn’t sure what the issue was but I wouldn’t have an orange tag if I hadn’t added it. Then she finally checked my husband’s boarding pass and found that the agent at checkin had added my carryon to his boarding pass instead of mine. She sent me on my way without my orange tag. Was a bit embarrassing for me the tone she used with me assuming I was trying to get away with something.

Almost everything was outstanding. First, we boarded on time and the flight crew did a great job getting everyone seated. Then the pilots took their time and care to make sure the plane was full de-iced three times as there was a bad ice storm a few hours earlier. The plane ride was smooth and comfortable and even the economy seats had decent room and comfort. Flight Attendant Lisa went above and beyond to make sure I was comfortable - she is outstanding. The only thing wrong with the flight, and it is something which needs to be addressed, is that the gate to gate time was over 6.5 hours and not one meal was served. The only thing offered to eat were two small cookies for a transcontinental flight - unacceptable. Charge me more but give me a meal for a long flight. Thankfully Lisa found something for me.

The only thing is if Wi-Fi is available after you land and taxi to the gate. It takes forever to get to the gate, and having the Wi-Fi continue would be great to bide the time at least 5 minutes before you arrive at the entrance. That is my only comment; otherwise, everything was good.

I got bumped due to weight restrictions even tho there were empty seats on my flight. I got put on an other flight with a stopover. My flight that originally was going to take 5-6 hours ever up being 14+ hours and my luggage arrived to my destination without me because I was made to check in my luggage on my original flight when I was deemed ok to board only to be asked to deplane. Worst flight experience.

Amazingly comfy flight - I had upgraded for a reasonable price and it was worth it. The food also was good.

Checking in at the counter was very disappointing. The lady had a very bad attitude and smart at me. She had no smile, did not greet me by name, or acknowledge me as a valued customer. Poor reflection of the airline.

Had to wait on pilot and crew to depart and had to wait to arrive at the gate because they only had 2 crews working. Delays, delays....Planes just keep getting smaller and tighter and they nickle and dime for everything. When will an airline actually wake up and make flying more enjoyable?

Angela was the best fa ever. She made that 8 hour flight a breeze

Kayak boarding information contained inaccuracies that would have not existed if booked directly with American. Paid for preferential boarding, was last to board.

I had two wonderful flights - very relaxing and got me there early!

What, first class and not even a cup of coffee before landing at 5 am in First Class? Really?

More groups for smother boarding, I didnt have any food. and there was no entertainment

Overall experience felt smooth and well-run. Inexpensive direct flight was great. Extreme "a-la-carte" business model got tiresome after a while. The $8 soft drink in-flight just felt excessive. Thin, hard, tightly-spaced seats were uncomfortable.

Spirit canceled the flight, sent no notification and then refused to issue a refund. Trash airline, will never fly again.

With this price, I shouldn't complain on anything. I understand I have to pay for every services they provide. The plane could smell a little better. Advise them to use frebeeze to freshen up the interior a little bit.

Not bad but I was told that I got a 1 carry. When I got to the gate I was told my purse was considered my carry on. I had never been told that before.

The flights were on time, the schedule was convenient for me, without delays.

Bare bones but a complimentary class of water doesn't seem like too much to ask.

You get what you pay for with this airline. If you want comfort be ready to pay, the regular seats are like hard plastic bus seats and they don't recline, so again you get what you pay for, a cheap flight that is just alright. Which is what I wanted.

Stop nickel and diming passengers with different seat costs, paying for water, carry on luggage, etc.

Boarding was smooth and on time. Flight itself was smooth (aside from some turbulence) and no glitches. On the downside, Spirit's no-frills service was as expected (no food or drink, cramped seating, extra cost for carry-ons, etc.), the announcements were nearly incomprehensible, and the constant niggling offers of upgrades and other services for sale (wifi, sandwiches, etc.) is annoying. Overall, a pleasant and uneventful experience - definitely worth the price.

Book cheap flights from Indianapolis to South Carolina

Recent round-trip flight deals

 
These are the cheapest round-trip flights from Indianapolis to South Carolina found on KAYAK in the last 72 hours.
3/10Mon
nonstopAllegiant Air
1h 48mIND-SAV
3/14Fri
nonstopAllegiant Air
1h 51mSAV-IND
$88
5/1Thu
1 stopSpirit Airlines
5h 04mIND-CLT
5/5Mon
1 stopSpirit Airlines
5h 00mCLT-IND
$99
3/6Thu
1 stopDelta
8h 12mIND-CAE
3/10Mon
1 stopDelta
7h 51mCAE-IND
$229
3/8Sat
1 stopUnited Airlines
6h 05mIND-CAE
3/11Tue
2 stopsUnited Airlines
8h 27mCAE-IND
$234
4/19Sat
1 stopDelta
6h 26mIND-GSP
4/22Tue
1 stopDelta
6h 28mGSP-IND
$247
5/1Thu
1 stopAmerican Airlines
4h 41mIND-CAE
5/5Mon
1 stopAmerican Airlines
4h 50mCAE-IND
$254
5/8Thu
1 stopAmerican Airlines
5h 50mIND-GSP
5/12Mon
1 stopAmerican Airlines
4h 26mGSP-IND
$262
3/8Sat
2 stopsUnited Airlines
7h 28mIND-CAE
3/11Tue
2 stopsUnited Airlines
7h 10mCAE-IND
$264
3/8Sat
1 stopSouthwest
4h 40mIND-CHS
3/11Tue
1 stopSouthwest
4h 40mCHS-IND
$272
5/3Sat
1 stopSouthwest
6h 00mIND-SAV
5/10Sat
1 stopSouthwest
5h 30mSAV-IND
$287

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Recent one-way flight deals

 
Only flying one-way? Below are some of the best one-way flight deals from Indianapolis to South Carolina found on KAYAK in the last 72 hours.
5/8Thu
1 stopFrontier
7h 05mIND-CLT
$51
4/10Thu
1 stopFrontier
5h 18mIND-CLT
$55
5/21Wed
1 stopSpirit Airlines
4h 51mIND-CHS
$56
3/11Tue
1 stopSpirit Airlines
22h 50mIND-CLT
$58
3/17Mon
nonstopAllegiant Air
1h 48mIND-SAV
$76
6/6Fri
nonstopAllegiant Air
1h 44mIND-CHS
$97
3/18Tue
1 stopAmerican Airlines
6h 28mIND-GSP
$124
3/11Tue
1 stopAmerican Airlines
6h 49mIND-SAV
$129
3/4Tue
1 stopDelta
4h 00mIND-CHS
$129
4/9Wed
1 stopDelta
5h 46mIND-CLT
$147

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Last minute flights from Indianapolis to South Carolina

Last minute flight, train and bus deals

 
These last-minute flight deals are the cheapest flights found on KAYAK in the last 72 hours for flights from Indianapolis to South Carolina that are departing in the next 10 days.
2/17Mon
multi-stop
14h 30mIND-CHS
2/24Mon
multi-stop
8h 19mCHS-IND
$284
2/16Sun
multi-stopAmerican Airlines
5h 56mIND-CAE
2/23Sun
multi-stopAmerican Airlines
4h 03mCAE-IND
$289
2/15Sat
multi-stopSpirit Airlines
14h 33mIND-CLT
2/17Mon
multi-stopSpirit Airlines
23h 15mCLT-IND
$385
2/13Thu
multi-stopSpirit Airlines
9h 36mIND-CHS
2/15Sat
multi-stopSpirit Airlines
6h 32mCHS-IND
$402
2/12Wed
multi-stopDelta
5h 27mIND-CLT
2/18Tue
multi-stopDelta
5h 09mCLT-IND
$481
2/12Wed
multi-stopDelta
3h 34mIND-CLT
2/16Sun
multi-stopDelta
4h 30mCLT-IND
$508
2/13Thu
multi-stopUnited Airlines
8h 11mIND-CAE
2/16Sun
multi-stopUnited Airlines
6h 45mCAE-IND
$509
2/16Sun
multi-stopUnited Airlines
4h 53mIND-CAE
2/23Sun
multi-stopUnited Airlines
17h 47mCAE-IND
$515
2/13Thu
multi-stopSouthwest
11h 55mIND-CLT
2/16Sun
multi-stopSouthwest
4h 05mCLT-IND
$532
2/13Thu
multi-stopSouthwest
8h 00mIND-CHS
2/15Sat
multi-stopSouthwest
11h 30mCHS-IND
$651

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Everything you need to know for your flight from Indianapolis to South Carolina

Information on your arrival and departure airports

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