GSP - DSM

$149 Find Cheap Flights from Greenville to Des Moines

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Greenville to Des Moines departing on 5/3. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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Search hundreds of travel sites at once for deals on flights to Des Moines

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Greenville to Des Moines, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Greenville to Des Moines, as well as popular online travel agencies
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Cheap Flight Deals from Greenville to Des Moines (GSP-DSM)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Greenville to Des Moines that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.

Recent round-trip flight deals from Greenville to Des Moines

Recommended round-trip deals departing in the coming months from the most popular airlines that fly from Greenville to Des Moines.
Discover the best prices and deals for you by selecting your travel dates.
Choose your dates
10:52 am - 5:06 pmGSP-DSM
7h 14m1 stop
6:30 pm - 11:43 pmDSM-GSP
4h 13m1 stop
$297Delta
Find Deal
Sat, May 3 - Sat, May 10
6:40 am - 2:33 pmGSP-DSM
8h 53m2 stops
2:20 pm - 9:56 pmDSM-GSP
6h 36m1 stop
$302American Airlines
Find Deal
Sat, May 3 - Sat, May 10
7:45 am - 2:33 pmGSP-DSM
7h 48m2 stops
11:51 am - 8:02 pmDSM-GSP
7h 11m2 stops
$307American Airlines
Find Deal
Sat, May 3 - Sat, May 10
12:00 pm - 7:07 pmGSP-DSM
8h 07m1 stop
6:35 pm - 11:38 pmDSM-GSP
4h 03m1 stop
$332Delta
Find Deal
Thu, Apr 3 - Sun, Apr 6
9:50 pm - 12:42 pmGSP-DSM
15h 52m1 stop
7:30 am - 3:05 pmDSM-GSP
6h 35m1 stop
$333Allegiant Air
Find Deal
Thu, Mar 6 - Mon, Mar 10
9:50 pm - 11:15 pmGSP-DSM
26h 25m2 stops
7:30 am - 3:05 pmDSM-GSP
6h 35m1 stop
$362Allegiant Air
Find Deal
Thu, Mar 6 - Mon, Mar 10
7:20 am - 3:30 pmGSP-DSM
9h 10m2 stops
5:25 am - 7:35 pmDSM-GSP
13h 10m2 stops
$403Southwest
Find Deal
Sat, Aug 2 - Mon, Aug 4
10:20 am - 9:30 pmGSP-DSM
12h 10m2 stops
5:40 am - 5:40 pmDSM-GSP
11h 00m2 stops
$409Southwest
Find Deal
Sat, May 3 - Wed, May 7
5:35 pm - 9:42 pmGSP-DSM
5h 07m1 stop
3:01 pm - 9:46 pmDSM-GSP
5h 45m1 stop
$437United Airlines
Find Deal
Mon, Aug 4 - Sat, Aug 16
6:00 am - 2:42 pmGSP-DSM
9h 42m2 stops
6:20 am - 11:54 amDSM-GSP
4h 34m1 stop
$442United Airlines
Find Deal
Tue, Aug 5 - Sun, Aug 10

Flights from Greenville to Des Moines - Travel Insights & Trends

Get data-powered insights and trends into flights from Greenville to Des Moines to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Greenville to Des Moines?

The average price of all round-trip flights from Greenville to Des Moines clicked on KAYAK for each day over the last 12 months.
If you are looking for a flight deal from Greenville to Des Moines, look for departures on Saturdays and avoid leaving on a Monday, as it's usually the priciest day. When flying back from Des Moines, Friday is the cheapest day to fly and Tuesday is the most expensive.

What is the cheapest month to fly from Greenville to Des Moines?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Greenville to Des Moines, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.
The cheapest month for flights from Greenville to Des Moines is September, where tickets cost $331 (return) on average. On the other hand, the most expensive months are June and December, where the average cost of round-trip tickets is $517 and $476 respectively.

Good to know

Low season

January

High season

February

Cheapest flight

$149
Best time to beat the crowds with an average 9% drop in price.
Most popular time to fly and prices are also 7% lower on average.
Flight from Greenville to Des Moines

When to book flights from Greenville to Des Moines

Are your dates flexible? Find out the best times to travel from Greenville to Des Moines based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Greenville to Des Moines

  • What is the cheapest flight from Greenville to Des Moines?

    In the last 3 days, the lowest price for a flight from Greenville to Des Moines was $149 for a one-way ticket and $297 for a round-trip.

  • Do I need a passport to fly between Greenville and Des Moines?

    Even though you are not required to have a passport, keep in mind that an official ID is needed to board the airplane.

  • Which airports will I be using when flying from Greenville to Des Moines?

    When flying out of Greenville you will be using Greenville. You will be landing at Des Moines, also known as Des Moines.

  • Which aircraft models fly most regularly from Greenville to Des Moines?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Greenville to Des Moines?

    oneworld, Star Alliance, and SkyTeam are the airline alliances operating flights between Greenville and Des Moines, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from Greenville to Des Moines, Delta or American Airlines?

    The two airlines most popular with KAYAK users for flights from Greenville to Des Moines are Delta and American Airlines. With an average price for the route of $396 and an overall rating of 8.0, Delta is the most popular choice. American Airlines is also a great choice for the route, with an average price of $366 and an overall rating of 7.2.

  • How does KAYAK find such low prices on flights from Greenville to Des Moines?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Greenville to Des Moines.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Greenville to Des Moines?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Des Moines from Greenville is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Greenville to Des Moines?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Des Moines with an airline and back to Greenville with another airline. Booking your flights between Greenville and DSM can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Greenville to Des Moines?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Des Moines from Greenville up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Top airlines flying from Greenville to Des Moines

 
See real verified KAYAK customer reviews for airlines flying from Greenville to Des Moines. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Greenville to Des Moines? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
DeltaOverall score based on 8220 reviews
7.9Entertainment
7.3Food
8.5Crew
8.0Comfort
8.2Boarding
Airline reviews

Boarding is, as it always is… horrible. Gate lice. Slow moving zones. Too many people with carry ons

10.0 ExcellentStephen, Feb 2025SFO - JFK
Read more Delta reviews

Boarding is, as it always is… horrible. Gate lice. Slow moving zones. Too many people with carry ons

I loved having a most black flight crew during Black History Month; rather by design or accident I appreciated the representation. ❤️

This was the second flight this week with flight attendant Marcus I’m not sure if his last name is Lane or Lang but this guy is awesome. He funny, attentive and his service is 5 stars. Marcus makes business travel more enjoyable !

Although the flight left late, we arrived early. It was one of the quickest boarding and off boarding experiences I’ve had. It was kind of annoying the only drinks they had were water, coffee, and tea. The flight was very smooth, temperature was just right, and flight attendants were friendly.

Lower number on this flight so spaced out passengers. Able to enjoy more room to relax during flight. It was lovely.

Kind staff. Snacks are small but that’s the new normal.

The young man who was our flight attendant in first class was lazy and did not do his job well at all. Never offered drinks upon boarding - actually I take that back... said "are you okay with water" as if I do not want to get you anything else, only passed the snacks around once, got my drink order wrong and then never offered a second round of drinks. He was the worst I have ever seen on Delta and we fly a lot.

Great service. Great staff. Boarding was a little slow, but I think there was a service dog slowing things down.

Flight left early and arrived early. the whole trip was excellent.

Seats were really tight and the seat belts did not give enough slack.

The boarding experience was good; $20 for wifi per flight is uncompetitive compared to Delta, Southwest, and others, and puts American lower on my list given similar pricing.

Great experience. Flight boarded easily. Departed early. Smooth flight. Great arrival in DC--almost no taxing! Almost direct to gate from runway. Crew was terrific. Same cookies and beverages in main cabin. I did not use the entertainment system on this flight.

Delays on all NY flights. There was no communication on why but they didn’t say it was weather. Other carriers were not delayed.

The flights were terribly delayed and then cancelled which forced us booking another night at the hotel. Very poor management from American Airlines

Extraordinary service in business class, and very good breakfast and snacks. A really lovely flight.

I flew out of Reagan National. My flight was delayed, delayed, delayed, and then canceled ...THREE TIMES over TWO DAYS. Staff were seemingly not empowered to provide information on why the flights were screwed up. A real nightmare.

They cancelled our flight without warning OR a refund. Never doing business with American Airlines again! This is the second AA booked trip in a row that we've had challenges with.

Crew was late. Baggage was late. 2hs inside the plane waiting fro de-icing and traffic. A 3:30hs flight ended up being almost 6hs inside the airplane.

Flight delayed on both ends - have a gate ready at DCA, don't make us sit for 30min after being late to take off as well.

The seats were crammed and the guy in front of me wouldn't stop reclining. If AA is cramming extra rows in, they need to take away the reclining in coach. My knees were smashed for 4 1/2 hours and I was very close to confronting the passenger in front of me.

Everything you need to know for your flight from Greenville to Des Moines

Information on your arrival and departure airports

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