$39 Find Cheap Flights from Detroit to South Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Detroit to South Carolina departing on 3/5. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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These are the airlines KAYAK users have selected most often from within our search results in flight searches from Detroit to South Carolina, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Detroit to South Carolina, as well as popular online travel agencies
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Best South Carolina Flight Deals from Detroit

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours

Charleston
Charleston1 stop$84
Myrtle Beach
Myrtle Beach1 stop$131
Greenville
Greenville2 stops$250
Columbia
Columbia1 stop$249
Florence
Florence1 stop$580

Good to know

Low season

December

High season

May

Cheapest flight

$39
Best time to beat the crowds but there is an average 13% increase in price.
Most popular time to fly with an average 1% increase in price.
Flight from Detroit to Charlotte

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Detroit to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Detroit to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Detroit to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Detroit to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Detroit to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Detroit to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Detroit to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Detroit to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Top tips for finding cheap flights to South Carolina

  • Looking for a cheap flight? 25% of our users found tickets from Detroit to the following destinations at these prices or less: Charlotte $164 one-way - $318 round-trip
  • Book at least 1 week before departure in order to get a below-average price.
  • High season is considered to be October, November and December. The cheapest month to fly from Detroit is September.
  • Morning departure is around 13% more expensive than an evening flight, on average*.
See more tips
*Average of the lowest prices shown in KAYAK’s search results for departures within the next 30 days

Top 4 airlines serving from Detroit to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Detroit to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Detroit to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.1
SouthwestOverall score based on 4587 reviews
7.1Food
8.2Boarding
7.7Entertainment
8.1Comfort
8.7Crew
Airline reviews

Gate agents were informative and friendly… flight attendants were as well. Had a fun time chatting about their legacy AirTran experiences as a former fan of the airline that Southwest acquired.

10.0 ExcellentAnonymous, Jan 2025ATL - LGA
Read more Southwest reviews

Gate agents were informative and friendly… flight attendants were as well. Had a fun time chatting about their legacy AirTran experiences as a former fan of the airline that Southwest acquired.

Flight was awfully bumpy and landing was a bit jolting. I was in the restroom when snacks and drinks were served and was not asked if i wanted any. I had to ask for water finally.

Wi Fi was horrible kept cutting out the whole time and too expensive

I really like open seating. I hate that I've heard this is going away. This is one of the unique things that makes Southwest my goto choice.

Boarding was a little late, but made up for it. It was quick to taxi to the runway, since it's a smallish airport.

Excellent! Only question is how we check in at exactly 24 hours in advance and end up at the end of the B boarding group

Multiple delays and gate changes. Arrived at final destination 6 hours late. All rental cars had been taken.

Employees were kind and funny, as always! Flight was late but no announcements were made for people with tight connections to help them transition quickly. No service due to turbulence.

It was 2 hours 45 minutes late, for no apparently clear reason.

I recently flew Southwest from San Jose to Honolulu. I was very impressed with the flight crew, especially the flight attendant in charge of the front of the plane. She came through the aisle at least five times for drinks and water, and two times for snacks. I have not seen such service since I flew first class. Also, for the first time, they gave us the correct baggage claim number, and the luggage came out quickly. I can't wait for Southwest to have assigned seating! I absolutely hate the Cattle Call boarding procedure and the mad dash to get seats and overhead bins. However, the boarding was efficient.

Great service. Great staff. Boarding was a little slow, but I think there was a service dog slowing things down.

Flight left early and arrived early. the whole trip was excellent.

Seats were really tight and the seat belts did not give enough slack.

I like in St George and prefer to fly out of CDC than SGU. Hopefully, they will continue the flights out of Cedar

Broken jer bridge. Poor communication about it. Lost 2 of 4 luggage pieces

Overall, it was okay. Seat was a little cramped. Would’ve liked more substantial snacks or opportunity to buy some.

All fine save for the abominable catering. Really gone downhill. We found it all inedible.

I appreciated friendly service from check-in, to boarding, to in-flight amenities! Attendants were accommodating and helpful. Thank you! Elaine

Was unsure of this flight due to high winds in CVG from Hurricane Helene. Crew did a great job of getting us to CVG safely.

5 hour delay. They blamed the weather but it was the computer issues they had been dealing with for days.

This was a pleasant, short flight and the crew was friendly.

Very poor. Our special services attendant gave us incorrect information. I also was mishandled at landing. There was no wheelchair waiting. I fell deboarding the plane. Appalling!

It was good. It’s been a long time since my wife and I fly any where and things have changed. Our trip was to see our new grandson. We fly economy and that was not good for my bad back. It was a quick flight but uncomfortable.

I paid for what I got which was cheap, I brought my own entertainment. I knew what to expect, so I could be prepared. If you’re flying economy, check in early like me. I have no problems with my flight, was on time, staff were friendly, and overall good experience.

Boarded over an hour late, no communication, the sign just changed, no attendant to answer questions - she disappeared forever (hiding). Small plane and couldn’t hear the overhead nor understand.

Service in first class no longer exists on American Airlines .

Customer service in first class does not exist on American Airlines

I never have a good experience with American and this was no different. The airplane was INCREDIBLY hot. Like unbearably so. Everyone was fanning themselves with pamphlets and sweating. When someone asked the flight attendant to turn down the temperature they were told there was nothing the crew could do. Once we pushed back from the gate we then had to wait an hour to take off and the communication from the crew was not good. People were getting up this whole time and a man was even in the bathroom when we took off. Once we landed at our destination we waited another 30 minutes at the gate to deplane with, again, no communication from the crew as to what was going on.

Flight was delayed due to a steering issue with plane. The delay caused me to miss the connecting flight. The delay caused me to spend an extra 21 hours in airports and flights to get to my destination. The plane issue obviously should have been found and fixed before we even boarded. Ridiculous.

First, to be fair, the flight was on time and the trip through the air was relatively smooth. But the flight was full, and they were checking carryons. As this process went on, the crew got increasingly rude and overbearing. During the drink service, a young girl (maybe 9) who had gotten up to use the lavatory got stuck behind the cart. At some point, she started feeling fearful and overwhelmed. Passengers noticed this and asked the crew to let her return to her seat. They refused. Then she started crying, and they still refused to move the cart forward to let her sit. The poor girl was trying to be brave and compose herself. The crew handled the situation terribly and with zero grace or decency. That episode, to me, encapsulates AA’s attitude toward its passengers. Disgraceful. The plane itself was cramped and miserable, as usual. There was zero inflight media or entertainment, other than the lane and borderline inappropriate jokes the steward made during the safety briefing. Then, of course, it took the better part of an hour for the checked bags to show up at the carousel. AA is no better than the el cheapo airlines these days and a far, far cry from its former self.

You get what you pay for with this airline. If you want comfort be ready to pay, the regular seats are like hard plastic bus seats and they don't recline, so again you get what you pay for, a cheap flight that is just alright. Which is what I wanted.

Stop nickel and diming passengers with different seat costs, paying for water, carry on luggage, etc.

Boarding was smooth and on time. Flight itself was smooth (aside from some turbulence) and no glitches. On the downside, Spirit's no-frills service was as expected (no food or drink, cramped seating, extra cost for carry-ons, etc.), the announcements were nearly incomprehensible, and the constant niggling offers of upgrades and other services for sale (wifi, sandwiches, etc.) is annoying. Overall, a pleasant and uneventful experience - definitely worth the price.

Lower cost is the reason to fly Spirit. Should give free baggage with credit card.

From gate to flight crew... All Spirit employees were great! Everyone was kind and helpful. Ride was almost smooth... A few bumps... But no problems. Seats were tight and uncomfortable. Our biggest issue was no free drinks. I can understand paying for adult beverages and can understand no snacks on a 3 hour flight... But no drinks???? I had to pay $4 for an apple juice for my son. That's not right. You should probably reconsider that.

- flight attendants not very friendly. - Paid for WiFi and plane didn’t have it working , never got a refund.

Great! First time flying with Spirit and I definitely loved it!

Not efficient. Missed my connecting flight over improper operation of spirit crew.

The boarding was quick and orderly, but the seating is tight and not in a good way.

WiFi didn’t work despite paying for it. Crew was nice.

Book cheap flights from Detroit to South Carolina

Recent round-trip flight deals

 
These are the cheapest round-trip flights from Detroit to South Carolina found on KAYAK in the last 72 hours.
2/25Tue
1 stopSpirit Airlines
5h 45mDTW-CLT
2/26Wed
1 stopSpirit Airlines
5h 59mCLT-DTW
$64
2/26Wed
1 stopSpirit Airlines
5h 45mDTW-CLT
3/5Wed
1 stopSpirit Airlines
13h 34mCLT-DTW
$82
2/26Wed
1 stop
5h 45mDTW-CLT
3/5Wed
1 stop
12h 18mCLT-DTW
$99
2/26Wed
1 stop
5h 45mDTW-CLT
3/3Mon
1 stop
12h 23mCLT-DTW
$112
2/27Thu
nonstopDelta
1h 59mDTW-CLT
3/3Mon
nonstopDelta
1h 55mCLT-DTW
$197
3/11Tue
1 stopAmerican Airlines
6h 43mDTW-MYR
3/17Mon
1 stopAmerican Airlines
7h 43mMYR-DTW
$197
4/8Tue
nonstopDelta
1h 56mDTW-MYR
4/16Wed
nonstopDelta
1h 56mMYR-DTW
$199
2/27Thu
1 stopSouthwest
5h 25mDTW-MYR
3/4Tue
2 stopsSouthwest
11h 30mMYR-DTW
$202
2/25Tue
2 stopsSouthwest
7h 40mDTW-CHS
3/4Tue
2 stopsSouthwest
10h 40mCHS-DTW
$207
2/15Sat
1 stopAmerican Airlines
6h 23mDTW-AGS
2/22Sat
1 stopAmerican Airlines
4h 28mAGS-DTW
$218

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Recent one-way flight deals

 
Only flying one-way? Below are some of the best one-way flight deals from Detroit to South Carolina found on KAYAK in the last 72 hours.
3/5Wed
1 stopSpirit Airlines
6h 06mDTW-CLT
$39
3/26Wed
1 stopSpirit Airlines
5h 19mDTW-CHS
$43
4/8Tue
1 stopFrontier
11h 28mDTW-CLT
$61
4/7Mon
1 stopFrontier
6h 53mDTW-CLT
$63
2/26Wed
nonstopDelta
1h 56mDTW-CLT
$99
4/29Tue
1 stopAmerican Airlines
5h 30mDTW-MYR
$99
4/29Tue
1 stopSouthwest
6h 20mDTW-CHS
$99
4/29Tue
1 stopSouthwest
4h 30mDTW-CLT
$109
2/25Tue
1 stopDelta
10h 39mDTW-CHS
$127
2/17Mon
1 stopAmerican Airlines
5h 47mDTW-CHS
$149

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Last minute flights from Detroit to South Carolina

Last minute flight, train and bus deals

 
These last-minute flight deals are the cheapest flights found on KAYAK in the last 72 hours for flights from Detroit to South Carolina that are departing in the next 10 days.
2/3Mon
multi-stopSpirit Airlines
14h 35mDTW-CHS
2/5Wed
multi-stopSpirit Airlines
11h 39mCHS-DTW
$213
2/3Mon
multi-stopSpirit Airlines
34h 45mDTW-CHS
2/5Wed
multi-stopSpirit Airlines
11h 39mCHS-DTW
$255
1/31Fri
nonstopDelta
2h 04mDTW-CLT
2/3Mon
nonstopDelta
1h 56mCLT-DTW
$329
1/31Fri
nonstopDelta
1h 57mDTW-CLT
2/3Mon
multi-stopDelta
4h 20mCLT-DTW
$339
2/2Sun
multi-stop
8h 58mDTW-CLT
2/4Tue
multi-stop
22h 45mCLT-DTW
$346
2/3Mon
multi-stopSouthwest
12h 40mDTW-CLT
2/10Mon
multi-stopSouthwest
8h 10mCLT-DTW
$359
2/3Mon
multi-stopSouthwest
12h 40mDTW-CLT
2/10Mon
multi-stopSouthwest
11h 20mCLT-DTW
$369
2/3Mon
multi-stop
8h 25mDTW-SAV
2/24Mon
multi-stop
19h 28mSAV-DTW
$380
1/31Fri
multi-stopAmerican Airlines
5h 03mDTW-FLO
2/3Mon
multi-stopAmerican Airlines
3h 39mFLO-DTW
$514
1/31Fri
multi-stopAmerican Airlines
8h 17mDTW-FLO
2/3Mon
multi-stopAmerican Airlines
4h 17mFLO-DTW
$524

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Everything you need to know for your flight from Detroit to South Carolina

Information on your arrival and departure airports

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