$41 Find Cheap Flights from Detroit to South Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Detroit to South Carolina departing on 4/21. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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These are the airlines KAYAK users have selected most often from within our search results in flight searches from Detroit to South Carolina, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Detroit to South Carolina, as well as popular online travel agencies
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Best South Carolina Flight Deals from Detroit

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours

Charleston
Charleston1 stop$84
Myrtle Beach
Myrtle Beach1 stop$99
Greenville
Greenville1 stop$191
Columbia
Columbia1 stop$278
Florence
Florence1 stop$296

Good to know

Low season

January

High season

May

Cheapest flight

$41
Best time to beat the crowds with an average 6% drop in price.
Most popular time to fly and prices are also 1% lower on average.
Flight from Detroit to Charleston

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Detroit to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Detroit to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Detroit to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Detroit to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Detroit to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Detroit to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Detroit to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Detroit to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Top tips for finding cheap flights to South Carolina

  • Looking for a cheap flight? 25% of our users found tickets from Detroit to the following destinations at these prices or less: Charlotte $154 one-way - $306 round-trip
  • Book at least 1 week before departure in order to get a below-average price.
  • High season is considered to be October, November and December. The cheapest month to fly from Detroit is September.
  • Morning departure is around 29% more expensive than an evening flight, on average*.
See more tips
*Average of the lowest prices shown in KAYAK’s search results for departures within the next 30 days

Top 4 airlines serving from Detroit to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Detroit to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Detroit to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.1
SouthwestOverall score based on 4333 reviews
8.2Boarding
8.1Comfort
7.6Entertainment
8.7Crew
7.1Food
Airline reviews

WiFi on the flight was not working. Thus, entertainment options were limited.

8.0 ExcellentJames, Feb 2025SRQ - DEN
Read more Southwest reviews

WiFi on the flight was not working. Thus, entertainment options were limited.

Great flight staff. Ease of boarding. Overall, very uneventful and easy trip.

Plane late from DC to Austin 30 minutes. Crew made up much of the time enroute to San Diego.

Gate agents were informative and friendly… flight attendants were as well. Had a fun time chatting about their legacy AirTran experiences as a former fan of the airline that Southwest acquired.

Flight was awfully bumpy and landing was a bit jolting. I was in the restroom when snacks and drinks were served and was not asked if i wanted any. I had to ask for water finally.

Wi Fi was horrible kept cutting out the whole time and too expensive

I really like open seating. I hate that I've heard this is going away. This is one of the unique things that makes Southwest my goto choice.

Boarding was a little late, but made up for it. It was quick to taxi to the runway, since it's a smallish airport.

Excellent! Only question is how we check in at exactly 24 hours in advance and end up at the end of the B boarding group

Multiple delays and gate changes. Arrived at final destination 6 hours late. All rental cars had been taken.

Seats are much much more comfortable than United, which is what I usually fly

Zero updates from the pilots for 30 minutes in the tarmac

Boarding is, as it always is… horrible. Gate lice. Slow moving zones. Too many people with carry ons

I loved having a most black flight crew during Black History Month; rather by design or accident I appreciated the representation. ❤️

This was the second flight this week with flight attendant Marcus I’m not sure if his last name is Lane or Lang but this guy is awesome. He funny, attentive and his service is 5 stars. Marcus makes business travel more enjoyable !

Although the flight left late, we arrived early. It was one of the quickest boarding and off boarding experiences I’ve had. It was kind of annoying the only drinks they had were water, coffee, and tea. The flight was very smooth, temperature was just right, and flight attendants were friendly.

Rode in a smaller plane and short trip meant no snacks, no free wifi or tv. It was only 30min flight so honestly wasn’t a big deal to lack these items.

Lower number on this flight so spaced out passengers. Able to enjoy more room to relax during flight. It was lovely.

Kind staff. Snacks are small but that’s the new normal.

The young man who was our flight attendant in first class was lazy and did not do his job well at all. Never offered drinks upon boarding - actually I take that back... said "are you okay with water" as if I do not want to get you anything else, only passed the snacks around once, got my drink order wrong and then never offered a second round of drinks. He was the worst I have ever seen on Delta and we fly a lot.

Standard. No different than a discount carrier on a short trip.

At least it was a short flight. Greyhound with wings.

They have lost any customer service care and support. Terrible airline now and been for awhile.

April was the flight attendant in first class and was the most pleasant, cordial and efficient person I have seen on a flight in years. Good example of the type of people AA should hire to increase customer satisfacdtion.

Everything was great. Boarding, early departure, early arrival, and deplaning were smooth. Smooth flight.

Two flight changes before the scheduled flight. On the day of the flight, the flight was delayed, which caused the connecting flight to be missed. Then, I was directed to another airport (CUN) and traveled to Tulum. American gave a $12 voucher for lunch. The least expensive item on the menu at a Mexican restaurant was $9.99. Driving to Tulum was a bad auto crash, and traffic was delayed two-plus hours. The bottom line is that we should have been at the hotel at noon, but it ended up at 11:30 PM.

The flight was delayed leaving Miami. When we arrived in Charlotte, we were unable to park at our scheduled gate. We had to wait another 30-45 minutes before we could park at a different gate. All in all, we were delayed by almost two hours arriving in Charlotte.

Bigger seats. Board back to front! Disembark front to back!

We were delayed Al ost / hours after boarding so that maintenance had to add oil to the engines. Then the oil they grabbed had been left out in the Dallas record cold and was frozen. They had to go back to the hanger and grab some that was not frozen.

It was a code share with Alaska - would have been great if I actually made it on the plane, claimed I didn’t have a ticket or a seat even thought I was checked in.

Friendly staff put me at ease with processes, since this was my first time. I would recommend flying on Spirit!

I lijed the friendliness of the crew and that we were on time.

There should be a “Ticketing/Check In” section. A Spirit employee helped us operate the self-serve check-in kiosk, and he was very helpful. However, the ticket agent was another story. She took our (2) checked bags, but when placing them on the conveyor, dropped one of them - it fell over on the conveyor and broke the retractable handle. Two pieces of the handle broke away and landed behind the counter. She knew what had happened, but chose to ignore and moved on to the next person in line.

Pl meed tp make proper accom for all pets and owners by placing them on a section to accommodate human animal allergies and give up a few seats YWS ACCOMMODATIONS SHOULD BE MADEBY THE AIRLINES and not pushed off to another paying customer that has to sit in fear or by being touched by someone elses animal.

hassled about bringing my laptop on in addition to my backpack...people boarding with real luggage were not stopped but I was which was ridiculous....zero comfort on board and everything is extra. Last time flying spirit not worth it

A passenger got into a verbal altercation with the flight attendant, who neither de-escalated nor acted professionally. Because of this, we had to go back to the gate for the person to be kicked off the flight. It delayed us 75 minutes.

Our experience was not a good one. Our flight got cancelled and was not given any accommodations due to the inconvenience. We lost time on our vacation due to this inconvenience

Helpful flight attendant. Awful legroom. Airline should be required by law to offer people a glass of water.

They are very particular about size of the bag. Mine is small bag and has wheels. Bag wheel edges are bit outside of the measurements bucket. They charged $99 as carryon bagage

Boarding was not clear; no announcement about delay. My sister and kid were seated separately for me and even though there were tons of seats up front, they wouldn't let us switch.

Book cheap flights from Detroit to South Carolina

Recent round-trip flight deals

 
These are the cheapest round-trip flights from Detroit to South Carolina found on KAYAK in the last 72 hours.
3/19Wed
1 stopSpirit Airlines
5h 19mDTW-CHS
3/25Tue
1 stopSpirit Airlines
11h 44mCHS-DTW
$84
3/19Wed
1 stopSpirit Airlines
5h 19mDTW-CHS
3/25Tue
1 stopSpirit Airlines
9h 38mCHS-DTW
$85
4/2Wed
1 stop
8h 47mDTW-CLT
4/9Wed
1 stop
8h 56mCLT-DTW
$132
4/3Thu
1 stop
26h 25mDTW-SAV
4/7Mon
1 stop
22h 51mSAV-DTW
$159
4/12Sat
1 stopDelta
5h 49mDTW-SAV
4/17Thu
nonstopDelta
2h 11mSAV-DTW
$169
4/26Sat
1 stopDelta
5h 04mDTW-SAV
5/3Sat
1 stopDelta
6h 56mSAV-DTW
$179
4/1Tue
2 stopsSouthwest
8h 45mDTW-SAV
4/8Tue
1 stopSouthwest
4h 30mSAV-DTW
$184
3/31Mon
1 stopSouthwest
6h 05mDTW-SAV
4/2Wed
1 stopSouthwest
5h 15mSAV-DTW
$188
5/30Fri
nonstopAmerican Airlines
1h 53mDTW-CLT
5/30Fri
1 stopAmerican Airlines
8h 00mCLT-DTW
$192
3/24Mon
1 stopAmerican Airlines
3h 56mDTW-SAV
3/25Tue
1 stopAmerican Airlines
3h 51mSAV-DTW
$197

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Recent one-way flight deals

 
Only flying one-way? Below are some of the best one-way flight deals from Detroit to South Carolina found on KAYAK in the last 72 hours.
4/21Mon
1 stopSpirit Airlines
12h 18mDTW-CHS
$41
5/5Mon
1 stopSpirit Airlines
7h 36mDTW-CHS
$43
3/17Mon
1 stop
10h 51mDTW-SAV
$84
3/17Mon
2 stops
16h 56mDTW-SAV
$89
4/2Wed
2 stopsSouthwest
8h 45mDTW-SAV
$95
4/26Sat
1 stopAmerican Airlines
4h 40mDTW-SAV
$105
4/2Wed
1 stopAmerican Airlines
3h 52mDTW-SAV
$106
6/3Tue
2 stopsSouthwest
8h 15mDTW-CHS
$114
4/2Wed
1 stopDelta
10h 38mDTW-CHS
$129
4/1Tue
2 stopsDelta
11h 59mDTW-CHS
$135

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Last minute flights from Detroit to South Carolina

Last minute flight, train and bus deals

 
These last-minute flight deals are the cheapest flights found on KAYAK in the last 72 hours for flights from Detroit to South Carolina that are departing in the next 10 days.
3/8Sat
multi-stopSpirit Airlines
17h 05mDTW-CLT
3/16Sun
multi-stopSpirit Airlines
13h 35mCLT-DTW
$230
3/7Fri
multi-stop
16h 19mDTW-CLT
3/10Mon
multi-stop
24h 42mCLT-DTW
$237
3/7Fri
multi-stopFrontier
6h 59mDTW-CLT
3/15Sat
multi-stopFrontier
24h 09mCLT-DTW
$253
3/7Fri
multi-stopFrontier
6h 59mDTW-CLT
3/10Mon
multi-stopFrontier
12h 24mCLT-DTW
$267
3/8Sat
nonstopDelta
1h 57mDTW-CLT
3/11Tue
nonstopDelta
1h 51mCLT-DTW
$285
3/8Sat
multi-stopDelta
6h 34mDTW-CLT
3/11Tue
nonstopDelta
1h 52mCLT-DTW
$295
3/7Fri
nonstopAmerican Airlines
2h 12mDTW-CLT
3/15Sat
nonstopAmerican Airlines
1h 47mCLT-DTW
$306
3/6Thu
nonstopAmerican Airlines
2h 00mDTW-CLT
3/8Sat
nonstopAmerican Airlines
1h 45mCLT-DTW
$320
3/6Thu
multi-stopSouthwest
10h 15mDTW-CLT
3/8Sat
multi-stopSouthwest
10h 20mCLT-DTW
$469
3/7Fri
multi-stopSouthwest
12h 35mDTW-CLT
3/9Sun
multi-stopSouthwest
10h 00mCLT-DTW
$504

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Everything you need to know for your flight from Detroit to South Carolina

Information on your arrival and departure airports

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