$110 Find Cheap Flights from Detroit to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Detroit to South America departing on 2/12. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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Best South America Flight Deals from Detroit

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours

Lima
Lima1 stop$409
Bogotá
Bogotá1 stop$348
Sao Paulo
Sao Paulo2 stops$736
Cartagena
Cartagena1 stop$293
Santiago
Santiago3 stops$732
Quito
Quito3 stops$555
Cali
Cali1 stop$305
Cusco
Cusco2 stops$878
Montevideo
Montevideo2 stops$905
Barranquilla
Barranquilla1 stop$255

Good to know

Low season

September

High season

December

Cheapest flight

$110
Best time to beat the crowds but there is an average 1% increase in price.
Most popular time to fly with an average 26% increase in price.
Flight from Detroit to Cartagena

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Detroit to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Detroit to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Detroit to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Detroit to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Detroit to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Detroit to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Detroit to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Detroit to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Top tips for finding cheap flights to South America

  • Book at least 1 week before departure in order to get a below-average price.
  • High season is considered to be January, November and December. The cheapest month to fly from Detroit is May.
  • Morning departure is around 14% more expensive than an evening flight, on average*.
*Average of the lowest prices shown in KAYAK’s search results for departures within the next 30 days

Top 5 airlines serving from Detroit to South America

Need help choosing which airline to fly with from Detroit to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
DeltaOverall score based on 8604 reviews
8.6Crew
7.3Food
7.9Comfort
7.9Entertainment
8.2Boarding
Airline reviews

The dear was very limited in space. I could put my water bottle in seat basket. Also, there was no inflight entertainment in the delta app?

10.0 ExcellentFreddy, Dec 2024JFK - MKE
Read more Delta reviews

The dear was very limited in space. I could put my water bottle in seat basket. Also, there was no inflight entertainment in the delta app?

Typically I give delta excellent reviews. Our flight was delayed 2hrs, I was one of the fortunate ones who were able to get to my connecting flight. Also, annoying that on the connecting flight boarding personnel make me put away a small bag into my carryon. It small enough to put in back pocket seat, why hold me and the line up to just push it into my carryon.

Logan airport construction meant that boarding was chaotic crowded and delayed

Everything was great. Great service, excellent communication, and early arrival

We were forced to wait nearly 50 additional minutes before leaving the terminal.

Free Wi-Fi is good. That’s all - food mediocre, unfriendly crew, poor communication after trying to file a claim for my lost bag, which Delta didn’t even know was lost until I told them.

Delta flight attendants poorly managed the boarding process and overhead storage. My bag was checked last minute and no claim ticket was provided. My bag is now lost. Complete incompetence by all flight crew involved.

All fine save for the abominable catering. Really gone downhill. We found it all inedible.

I appreciated friendly service from check-in, to boarding, to in-flight amenities! Attendants were accommodating and helpful. Thank you! Elaine

Was unsure of this flight due to high winds in CVG from Hurricane Helene. Crew did a great job of getting us to CVG safely.

Very slow boarding, 1 hour late - uncomfortable chairs and crew barely speaking english even at the airport!

4 hours delay, awful food and missed all my connections because of the delay to be rebooks for a flight 10 hrs later back home and never actually make it to my final destination

Four handbag storages were damaged and sealed, limiting the space to store our things in the plane.

It was fine. no food or entertainment , but was only a 40 minute flight.

The boading process was fine. Had to wait for bus from tarmac to terminal. Had to go through 2 or 3 security checkpoints in Lima to make next connecting flight.

Routine and on time flight with pleasant stewards and decent food. Nice experience!

The crew was super friendly and respectful, they made me feel well all the fly , thanks delta

No food optional ( they offer just pasta, no second option, the soda without carbonation, I asked for snacks and they said give a minute, I never got it) I believe they (crew) don't care about it (people)

The seats are getting smaller and smaller. Very uncomfortable trip. More than in other airlines

My experience it was okay but have many thinks to be better. For example the food, the comfort.

Flight attendant walked away once they landed and we were forced to wait another hour after an already 3hr delay.

No overhead space so all carryons were checked. No internet.

The flight was on time and everything went very smoothly.

A thousand choices for movies and nothing to watch. I avoid 'R' rated shows and others with violence and sexual content, which results in a handful of flicks to view and I have them already.

I think I paid for an extra legroom seat and to be honest, there was not a lot of space available for my not very long legs. The flight was totally full and the staff did everything possible to meet the needs of all passengers. My only concern was for the size and spacing of my seat.

Typically, I am always impressed with American personnel. These you run into the rude old hags that are still around. I can tell over my 40 years of flying with them, they have made strides in improving their attitudes.

Two issues. The plane was old and dirty. The armrest looked like an old car that had the vinyl rubbed off. The Seats in these aircraft are about as hard and uncomfortable. I want to tour Italy for a month and I want to buy a one-way ticket to Thailand but I will not sit in the seats these planes have. It is seriously stupid how hard they are.

The seat could not recline. This was not indicated as such when I paid for the seat. So itvwad not the most comfortable ride. At boarding, the staff could have more pleasant even though it may be an intense time.

The seat could not recline. This was not indicated as such when I paid for the seat. So itvwad not the most comfortable ride.

The meals were mediocre and the alcohol selection was poor.

Lots of announcements that no wheeled carry on bags were allowed on the flight, yet the overhead bins were totally full and made it uncomfortable trying to get through and significantly held up departure. Why were they allowed on when they said that they weren't? Trash only came by soon after service and I wasn't ready to dispose of it. I had to first hold on to it and after flagging and attendant was told to stuff it in the seat back! I have never run into the need to walk outside in northern winter weather at an international airport and wasn't dressed to do so in the cold pouring rain! I'm not thinking that I'll be back unless I hear things have changed.

My first flight left so late we knew I would miss my connection. Rather than redirecting me then, they made me take a flight to Montreal, then Toronto (there was a flight leaving for Toronto when I was in NYC, no need for me to also go to montreal). Then they gave me a food voucher that did not work (4 places would not accept it). At least they gave me a hotel automatically, even though it was a cheap crappy one. I'm still not home, and it's been over 24 hours. I'm exhausted.

Liked the size of seats. Not much food offered given length of flight.

The boarding was at a dual gate hallway and there was only one spoken explanation about which way to turn to board the correct plane. It wasn't marked visually at the split in the gate. The phone charger did not work at my seat. The temperature was quite chilly throughout the flight and the recorded announcements were extremely loud for a small plane.

The Air Canada staff at the gate in Newark were fantastic and so very helpful!!!

Flight was delayed 1.5 hours as crew was stuck in traffic...that is absurd that the airline would be transfering a crew by car through NYC during rush hour. I missed my shuttle bus and got stuck in Vancouver for the night. Airline did not offer a voucher

I booked these flights for our group of 4 people several months in advance. On the departing flight, I checked in 24 hours before flight and was able to select the seats that we liked. On the return flight, I had no internet access until about 12 hours before flight, when I tried to check in, we were scattered all over the plane in middle seats which is absolutely ridiculous. I book all 4 ticket in 1 booking MONTHS in advance, the preassigned seats should be together, NOT scattered in 4 different rows in middle seats.

Very unfriendly crew, Air Canada should hire staff that are willing to do their job and be friendly to others. Unmannered flight attendants.

It was absolutely awful in every week. A mechanical failure led to a 6 hour delay, cancellation and rerouting.

On the short flight it was fine . The flight was smooth and crew pleasant .

I thought since I upgraded my seat I would get some perks. Free water, free snacks. Free carry on luggage.

Seats were surprisingly comfortable, and crew was polite. I did not like the baggage fee prices, the minimal amount of flight choices for my area and the difficulty of the self service bag drop.

Lost MacBook, had time to retrieve, but was told I had no time. Need Silver MacBook back

It’s ridiculous to pay for carry-on luggage. I also wasn’t given an option to specify I have carry on bag at time of ticket purchase. I also could not specify I have carry on luggage at time of online check-in.

I’ve now flown Spirit a few times and while the general perception of Spirit I feel is poor, I’ve had a great experience each time. They do charge extra for everything but you should know that going in

The people were wonderful, but I hated the way they over charged for luggage, especially for stops which were charged the same as starting point to final destination.

Horrible I paid for extra for better seats. At time of checking my seats were sold to someone else. I need a refund and more for my bad experience

First time flying Spirit and I was pleasantly surprised. Service was as advertised. Crew were very professional and friendly and excellent in dealing with a customer who felt ill on the flight.

Delayed fight LAS to LAX. OK, fog in LA, not your fault. But all your staff, onboard in in lounge, speak so fast, enunciate so poorly and often have a accent that it is impossible to understanding anything they are saying.

Very mean staff. No entertainment.. No WiFi, a baby cried for over 3 hours no staff offer to assist. My son $500 computer screen got damaged under the plane due to force check in of my bag. TERRIBLE EXPERIENCE!

Book cheap flights from Detroit to South America

Recent round-trip flight deals

1/14Tue
1 stopSpirit Airlines
7h 58mDTW-CTG
1/24Fri
1 stopSpirit Airlines
9h 41mCTG-DTW
$293
1/13Mon
1 stopSpirit Airlines
15h 23mDTW-CLO
1/22Wed
1 stopSpirit Airlines
18h 39mCLO-DTW
$305
4/8Tue
1 stopAmerican Airlines
14h 56mDTW-MDE
5/6Tue
1 stopAmerican Airlines
17h 23mMDE-DTW
$527
4/8Tue
2 stopsLATAM Airlines
10h 44mDTW-MDE
5/5Mon
2 stopsLATAM Airlines
16h 56mMDE-DTW
$535
4/13Sun
1 stopAmerican Airlines
7h 26mDTW-MDE
5/1Thu
1 stopAmerican Airlines
8h 25mMDE-DTW
$537
2/9Sun
2 stopsLATAM Airlines
15h 48mDTW-CLO
2/26Wed
2 stopsLATAM Airlines
16h 41mCLO-DTW
$560
3/13Thu
2 stopsDelta
13h 21mDTW-MDE
3/27Thu
2 stopsDelta
13h 55mMDE-DTW
$668
3/14Fri
2 stopsAir Canada
32h 45mDTW-BOG
3/21Fri
1 stopAir Canada
24h 06mBOG-DTW
$721
2/1Sat
2 stopsAir Canada
18h 05mDTW-BOG
2/8Sat
2 stopsAir Canada
24h 36mBOG-DTW
$726
4/5Sat
2 stopsDelta
15h 05mDTW-CTG
4/27Sun
2 stopsDelta
19h 41mCTG-DTW
$738

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Recent one-way flight deals

2/12Wed
1 stopSpirit Airlines
7h 21mDTW-CTG
$110
1/8Wed
2 stopsSpirit Airlines
21h 45mDTW-CTG
$111
3/13Thu
2 stopsAmerican Airlines
10h 38mDTW-CTG
$312
3/9Sun
2 stopsAmerican Airlines
9h 41mDTW-CTG
$322
2/4Tue
2 stopsAir Canada
17h 15mDTW-GIG
$536
2/4Tue
2 stopsAir Canada
31h 55mDTW-SDU
$536
2/10Mon
2 stopsDelta
16h 52mDTW-CLO
$569
4/25Fri
1 stopLATAM Airlines
14h 15mDTW-LIM
$613
2/5Wed
1 stopDelta
13h 55mDTW-GIG
$651
5/1Thu
3 stopsLATAM Airlines
21h 53mDTW-AEP
$732

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Last minute flights from Detroit to South America

Last minute flight, train and bus deals

12/23Mon
multi-stop
17h 25mDTW-CTG
1/17Fri
multi-stop
20h 22mCTG-DTW
$599
12/23Mon
multi-stop
15h 15mDTW-CTG
1/17Fri
multi-stop
20h 22mCTG-DTW
$636
12/23Mon
multi-stopSpirit Airlines
26h 26mDTW-CTG
1/17Fri
multi-stopSpirit Airlines
17h 54mCTG-DTW
$733
12/19Thu
multi-stopSpirit Airlines
19h 32mDTW-CTG
12/25Wed
multi-stopSpirit Airlines
9h 40mCTG-DTW
$758
12/22Sun
multi-stopLATAM Airlines
33h 39mDTW-CLO
1/19Sun
multi-stopLATAM Airlines
16h 07mCLO-DTW
$1,078
12/23Mon
multi-stopLATAM Airlines
31h 10mDTW-GRU
12/30Mon
multi-stopLATAM Airlines
24h 47mGRU-DTW
$1,262
12/23Mon
multi-stopAmerican Airlines
8h 45mDTW-BOG
12/26Thu
multi-stopAmerican Airlines
14h 55mBOG-DTW
$1,385
12/23Mon
multi-stopAmerican Airlines
14h 10mDTW-BOG
12/26Thu
multi-stopAmerican Airlines
10h 43mBOG-DTW
$1,389
12/22Sun
multi-stopDelta
24h 29mDTW-LIM
1/16Thu
multi-stopDelta
21h 20mLIM-DTW
$1,410
12/22Sun
multi-stopDelta
16h 25mDTW-LIM
1/16Thu
multi-stopDelta
16h 43mLIM-DTW
$1,419

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Everything you need to know for your flight to South America

Information on your arrival and departure airports

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