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$127 Find Cheap Flights from Detroit to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Detroit to South America departing on 12/11. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
0 bags

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Best South America Flight Deals

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours

Lima
Lima1 stop$505
Bogotá
Bogotá2 stops$505
Sao Paulo
Sao Paulo2 stops$664
Cartagena
Cartagena1 stop$374
Santiago
Santiago1 stop$784
Quito
Quito2 stops$596
Cali
Cali2 stops$344
Guayaquil
Guayaquil2 stops$453
Cusco
Cusco2 stops$951
Barranquilla
Barranquilla2 stops$335
Montevideo
Montevideo2 stops$870
Caracas
Caracas2 stops$1,985

Good to know

Low season

September

High season

December

Cheapest flight

$127
Best time to beat the crowds with an average 1% drop in price.
Most popular time to fly with an average 21% increase in price.
Flight from Detroit to Cartagena

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Detroit to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Detroit to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Detroit to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to South America from Detroit is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Detroit to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to South America with an airline and back to Detroit with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Detroit to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to South America from Detroit up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Top tips for finding cheap flights to South America

  • Morning departure is around 9% cheaper than an evening flight, on average*.
*Average of the lowest prices shown in KAYAK’s search results for departures within the next 30 days

Top 5 airlines serving from Detroit to South America

Need help choosing which airline to fly with from Detroit to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
DeltaOverall score based on 8788 reviews
7.9Comfort
8.2Boarding
8.5Crew
7.9Entertainment
7.3Food
Airline reviews

Crew was nice. Flight was timely. Seats could be better as well as the food considering it’s first class.

6.0 GoodAndrew, Nov 2024ALB - ATL
Read more Delta reviews

Crew was nice. Flight was timely. Seats could be better as well as the food considering it’s first class.

Left on time and arrived early this extending our 31 minute transfer. Bags made it also!

Good and consistent Printer in lounge did not work for me :(

Most of my discomfort was going through TSA. However, the Delta seats had inadequate leg room and I tried my very best to connect to the wi-fi and it was a cumbersome process that finally gave me the info that I needed to sign in AFTER I had completed the flight...Why make it so difficult to use? That said I really really appreciate the pilot taking a little extra time to avoid a bad storm area and both landings in Atlanta and Orlando were flawless to my delight!!!

Delayed in taking off because no flight crew. The in seat entertainment was working properly.

All fine save for the abominable catering. Really gone downhill. We found it all inedible.

I appreciated friendly service from check-in, to boarding, to in-flight amenities! Attendants were accommodating and helpful. Thank you! Elaine

Was unsure of this flight due to high winds in CVG from Hurricane Helene. Crew did a great job of getting us to CVG safely.

5 hour delay. They blamed the weather but it was the computer issues they had been dealing with for days.

Flight was delayed due to needing a replacement flight crew. Delta changed the aircraft type in Detroit. One hour delay. But once in the air, good flight

It was fine. no food or entertainment , but was only a 40 minute flight.

Routine and on time flight with pleasant stewards and decent food. Nice experience!

The crew was super friendly and respectful, they made me feel well all the fly , thanks delta

No food optional ( they offer just pasta, no second option, the soda without carbonation, I asked for snacks and they said give a minute, I never got it) I believe they (crew) don't care about it (people)

The seats are getting smaller and smaller. Very uncomfortable trip. More than in other airlines

My experience it was okay but have many thinks to be better. For example the food, the comfort.

For bus boarding, group 1 should have been sent on a separate bus ahead of the general boarding. It would have been nice.

You delayed my trip three days for no reason other than your lack of preparedness, did not offer any compensation, including food or a bed. I couldn’t trust you so I moved up my return flight and lost another day at the end of my trip to hopefully make sure I make my next flight. I will never fly LATAM again. You have the worse accountability and reliability and clearly do not care that your clients have lives and what it cost to fly to another country.

I do not speak Spanish or read in Spanish When asking for help, people were hard to find they spoke quickly and pointed a lot directions for where to go and what to do we’re unclear. Which made my traveling uneasy.

I do not read or speak in Spanish. Only English. When asking for help, the people spoke quickly in English and pointed a lot. I wish they would’ve spoken a little slower for me to understand. There was much confusion and hurried in their message and I was unclear as to where to go

My seat was very worn. Otherwise I had an excellent flight

I'm not a valued flyer so I'm always in the last group to board...that sucks, always

My flight back my reservations were list because they said I didn't pay my pet fee when I had a receipt

Flight was cancelled as I was in line for security. Next available flight got me to my destination 24 hrs later than the first. No refunds offered, just credit toward another flight. I booked with delta, got to my destination only 2 hrs behind my original flight schedule. Won’t be using American again.

Checked in the minute I was allowed and still wound up in group 8 for boarding.

boarding was quick and painless. entertainment could have been better- but that's also what ipads are for.

great experience. minimal lines at BWI. at DFW they got a long haul 787 boarded in 30 minutes

Overall flight was as expected. It would have been better with a couple options for snack instead of only one item and if there was a TV or music as option. But overall satisfied.

There were several issues with this flight. I have flown quite often internationally and I was surprised by the lack of presence of attendants other than meal and drink times. The food was not best but I feel that is the norm. We also had to get off the plane once in London via stairs and bus to the terminal. Anyone who had another flight had to then get another bus to another terminal. This causes me to miss my flight and have to rebook.

The flight from CLE to JFK was fantasti! Pilots and cre were informative and accommodating.

Problem with operation of on board entertainment computer. Failed about 1 /2 hour into the flight. Rebooting failed to restore.

Putting carryone size suitcase into the overhead luggage storage on a the small CR900 plane was cumbersome and its assignment to a far far gate w/o the moveable ramps at YYZ arrivals really stunk.

This flight was a lot more comfortable with more room than the Air Canada Rouge!!! We will never go rouge again! A yes to this one!!! It was so nice to have inflight entertainment! Also the carts came around twice for drinks or a snack!! Great experience all around!

AC flight attendants aren't overly friendly. Otherwise flight was fine.

Newark to Montreal was really good. The return flight was not so good with a substitute carrier was not as good. I was impressed by the AC staff all along the way. Their in flight stack was superior.

I’m handicapped and the staff and crew were so kind and helped me board and made sure I was fine during the flight.

The people are great! The trip to Japan is simply never ending!!! Not the problem of the airlines, though.

United agent at FLL excellent - due 55 min conx at ORD rerouted us on an earlier departure via DEN and got home 5 hours earlier than expected

I bought a ticket from Brussels to Fort Lauderdale, Florida, USA via Montreal. When I went to the airport, I learned that I needed a Canadian visa. When I bought the ticket online, there was no warning saying "If you are not a US or Canadian citizen; You need a Canadian visa." I asked for my money back, but the staff at the airport said they couldn't help me. I said, "Make the ticket open, I'll fly later," and they said no. I looked for this information on Air Canada's website. They've hidden it so well that it's impossible to find it easily. I understand that Air Canada makes millions of dollars in unfair profits by selling tickets this way. Why don't they ask when purchasing? They don't ask; because they're making money. Every year, perhaps thousands of tickets are subject to this situation. I will use all my rights and complain everywhere. Maybe they won't give me my money back, but I would advise anyone buying ticket to be careful from now on.

Friendlier staff who are nice to the elderly who need assistance

WiFi didn’t work despite paying for it. Crew was nice.

I upgraded my ticket at the ticket counter and was not informed of the huge bottleneck at TSA pre check. It took me over an hour to get through the line at this small airport and although I ran to the gate and reached it prior to scheduled departure, it had already pushed pack. I missed the flight. Spirit rebooked me on a flight to Orlando that evening, which would require me to then rent a car and drive to FLL. For scheduling reasons, I determined it be would better to rent a car in Pensacola and drive it to my destination in FLL. Spirit called me that evening and asked me if I was going to board the plane. I explained no, for scheduling reasons. The person apologized and said I would receive a refund, but I have not heard back. Certainly, I ought to be refunded the upgrade I paid for at the counter.

The staff from LAX to New Orleans were rude but the staff from New Orleans to LAX were nice!

Did what they needed to do. Brought us from point A to point B timely and without issue. Boarding through deplaning smooth.

Direct 2.5 hour flight good. Free snacks and coffee, water, or soft drinks not available...bad.

Atlanta airport gate area floor and nearly all seats disgusting. Spirit airlines crew fantastic!!

Over 2 hour delay due to “weather” but all other flights were taking off with no issues. We felt lied to the entire time as well.

Never been worse. Never again even if the ticket were free.

Everything was excellent and as expected. The boarding process was great but deboarding was a bit slow. No fault of the crew; it just seemed like the passengers didn’t want to leave! 😂

waited 5 hours to tell us it was cancelled even when they knew

Book cheap flights from Detroit to South America

Recent round-trip flight deals

1/14Tue
1 stopSpirit Airlines
7h 58mDTW-CTG
1/24Fri
2 stopsSpirit Airlines
18h 09mCTG-DTW
$374
12/2Mon
2 stopsSpirit Airlines
20h 51mDTW-CTG
12/5Thu
1 stopSpirit Airlines
12h 10mCTG-DTW
$379
2/22Sat
2 stopsAmerican Airlines
12h 24mDTW-MDE
2/27Thu
1 stopAmerican Airlines
16h 31mMDE-DTW
$565
3/1Sat
2 stopsAmerican Airlines
10h 03mDTW-MDE
3/26Wed
1 stopAmerican Airlines
9h 58mMDE-DTW
$566
3/19Wed
1 stopDelta
16h 21mDTW-CTG
3/27Thu
1 stopDelta
16h 58mCTG-DTW
$709
3/19Wed
1 stopDelta
16h 21mDTW-CTG
3/27Thu
2 stopsDelta
13h 11mCTG-DTW
$710
2/16Sun
1 stopLATAM Airlines
20h 47mDTW-CTG
2/24Mon
2 stopsLATAM Airlines
23h 22mCTG-DTW
$771
2/17Mon
1 stopLATAM Airlines
19h 47mDTW-CTG
2/20Thu
2 stopsLATAM Airlines
15h 43mCTG-DTW
$801
4/9Wed
2 stopsAir Canada
17h 15mDTW-EZE
4/23Wed
2 stopsAir Canada
18h 41mEZE-DTW
$871
12/27Fri
1 stopAir Canada
21h 35mDTW-BOG
12/29Sun
1 stopAir Canada
11h 16mBOG-DTW
$901

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Recent one-way flight deals

12/11Wed
1 stopSpirit Airlines
17h 23mDTW-CTG
$127
12/14Sat
2 stopsSpirit Airlines
21h 18mDTW-CTG
$131
3/1Sat
1 stopLATAM Airlines
7h 17mDTW-CTG
$336
1/22Wed
1 stopAir Canada
17h 35mDTW-BOG
$357
11/23Sat
2 stopsAir Canada
17h 15mDTW-BOG
$358
2/15Sat
1 stopLATAM Airlines
20h 47mDTW-CTG
$375
11/27Wed
2 stopsDelta
24h 05mDTW-MDE
$396
12/3Tue
1 stopAmerican Airlines
11h 49mDTW-LIM
$448
1/22Wed
1 stopAmerican Airlines
16h 30mDTW-BOG
$511
2/13Thu
2 stopsDelta
15h 15mDTW-LIM
$578

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Last minute flights from Detroit to South America

Last minute flight, train and bus deals

11/18Mon
multi-stop
14h 05mDTW-BOG
11/22Fri
multi-stop
17h 27mBOG-DTW
$430
11/18Mon
multi-stopAvianca
14h 05mDTW-BOG
11/20Wed
multi-stopAvianca
26h 43mBOG-DTW
$494
11/18Mon
multi-stop
35h 10mDTW-BOG
11/22Fri
multi-stop
17h 27mBOG-DTW
$495
11/16Sat
multi-stopSpirit Airlines
19h 08mDTW-CTG
11/22Fri
multi-stopSpirit Airlines
27h 50mCTG-DTW
$544
11/16Sat
multi-stopSpirit Airlines
23h 58mDTW-CTG
11/22Fri
multi-stopSpirit Airlines
27h 50mCTG-DTW
$572
11/18Mon
multi-stopAmerican Airlines
17h 30mDTW-LIM
12/9Mon
multi-stopAmerican Airlines
17h 58mLIM-DTW
$1,140
11/18Mon
multi-stopAmerican Airlines
15h 35mDTW-LIM
12/9Mon
multi-stopAmerican Airlines
13h 37mLIM-DTW
$1,145
11/17Sun
multi-stopAir Canada
12h 15mDTW-GRU
11/26Tue
multi-stopAir Canada
15h 11mGRU-DTW
$1,594
11/15Fri
multi-stopLATAM Airlines
31h 22mDTW-GRU
11/25Mon
multi-stopLATAM Airlines
30h 10mGRU-DTW
$2,014
11/15Fri
multi-stopLATAM Airlines
39h 02mDTW-GRU
11/25Mon
multi-stopLATAM Airlines
38h 37mGRU-DTW
$2,021

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Everything you need to know for your flight to South America

Information on your arrival and departure airports