$84 Find Cheap Flights from Detroit to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Detroit to South America departing on 5/13. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult

Search hundreds of travel sites at once for deals on flights to South America

Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 22% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Free to useThere are no hidden charges or fees.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Best South America Flight Deals from Detroit

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours

Lima
Lima2 stops$446
Bogotá
Bogotá1 stop$326
Sao Paulo
Sao Paulo2 stops$525
Cartagena
Cartagena1 stop$228
Santiago
Santiago1 stop$804
Quito
Quito2 stops$549
Cali
Cali2 stops$326
Guayaquil
Guayaquil2 stops$517
Cusco
Cusco2 stops$1,035
Montevideo
Montevideo3 stops$876
Barranquilla
Barranquilla2 stops$590

Good to know

Low season

September

High season

December

Cheapest flight

$84
Best time to beat the crowds with an average 5% drop in price.
Most popular time to fly with an average 28% increase in price.
Flight from Detroit to Cartagena

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Detroit to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Detroit to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Detroit to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Detroit to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Detroit to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Detroit to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Detroit to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Detroit to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Top tips for finding cheap flights to South America

  • Book at least 1 week before departure in order to get a below-average price.
  • High season is considered to be January, November and December. The cheapest month to fly from Detroit is April.
  • Morning departure is around 2% more expensive than an evening flight, on average*.
*Average of the lowest prices shown in KAYAK’s search results for departures within the next 30 days

Top 5 airlines serving from Detroit to South America

Need help choosing which airline to fly with from Detroit to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
DeltaOverall score based on 8220 reviews
7.3Food
8.0Comfort
8.5Crew
7.9Entertainment
8.2Boarding
Airline reviews

Boarding is, as it always is… horrible. Gate lice. Slow moving zones. Too many people with carry ons

10.0 ExcellentStephen, Feb 2025SFO - JFK
Read more Delta reviews

Boarding is, as it always is… horrible. Gate lice. Slow moving zones. Too many people with carry ons

I loved having a most black flight crew during Black History Month; rather by design or accident I appreciated the representation. ❤️

This was the second flight this week with flight attendant Marcus I’m not sure if his last name is Lane or Lang but this guy is awesome. He funny, attentive and his service is 5 stars. Marcus makes business travel more enjoyable !

Although the flight left late, we arrived early. It was one of the quickest boarding and off boarding experiences I’ve had. It was kind of annoying the only drinks they had were water, coffee, and tea. The flight was very smooth, temperature was just right, and flight attendants were friendly.

Rode in a smaller plane and short trip meant no snacks, no free wifi or tv. It was only 30min flight so honestly wasn’t a big deal to lack these items.

Lower number on this flight so spaced out passengers. Able to enjoy more room to relax during flight. It was lovely.

Kind staff. Snacks are small but that’s the new normal.

Overall, terrible. Flight from SFO was delayed due to “air traffic control issues”, and we were all mislead about connecting flights. Told “you have 20 minutes to catch your connection”. Reality was 5. We got to watch the plane sit at the bridge. Won’t fly Delta with a connection again.

The young man who was our flight attendant in first class was lazy and did not do his job well at all. Never offered drinks upon boarding - actually I take that back... said "are you okay with water" as if I do not want to get you anything else, only passed the snacks around once, got my drink order wrong and then never offered a second round of drinks. He was the worst I have ever seen on Delta and we fly a lot.

Great service. Great staff. Boarding was a little slow, but I think there was a service dog slowing things down.

I liked everything, this was classed as premium economy but it was much better than Lufthansas business class. Lovely staff, comfortable plane and an excellent seat arrangement. A very pleasant surprise.

No entertainment but not expected. Unless you are referring to monitor that you can use. Then Al, was fine on all flights.

Friendly staff, It was the first flight out for our plane, so had to be deiced from the frost. Only delayed a few minutes,

We boarded so late it caused us to miss time at Foz. No real information was provided to the passengers waiting.

Basic experience, we were delayed causing less time to enjoy our destination and on the way back, we boarded when the flight should have been taking off.

reliable, relatively relaxed, helpful and kind staff and clean airplanes. No need for more.

Only complaint is that the entertainment system wasn’t working on our seats and some others.

Very slow boarding, 1 hour late - uncomfortable chairs and crew barely speaking english even at the airport!

The flight itinerary was changed 3 times, I explain the problem on the previous leg.

Flight never happened because of previous flight delay. Sent back to the stays on a flight 10 hrs later without making to my final destination and still waiting full rugindo for it. So yeah not a good experience

Delays on all NY flights. There was no communication on why but they didn’t say it was weather. Other carriers were not delayed.

The flights were terribly delayed and then cancelled which forced us booking another night at the hotel. Very poor management from American Airlines

Extraordinary service in business class, and very good breakfast and snacks. A really lovely flight.

Same as before being upgraded to business class made it perfect

I flew out of Reagan National. My flight was delayed, delayed, delayed, and then canceled ...THREE TIMES over TWO DAYS. Staff were seemingly not empowered to provide information on why the flights were screwed up. A real nightmare.

They cancelled our flight without warning OR a refund. Never doing business with American Airlines again! This is the second AA booked trip in a row that we've had challenges with.

Crew was late. Baggage was late. 2hs inside the plane waiting fro de-icing and traffic. A 3:30hs flight ended up being almost 6hs inside the airplane.

Flight delayed on both ends - have a gate ready at DCA, don't make us sit for 30min after being late to take off as well.

The seats were crammed and the guy in front of me wouldn't stop reclining. If AA is cramming extra rows in, they need to take away the reclining in coach. My knees were smashed for 4 1/2 hours and I was very close to confronting the passenger in front of me.

This flight didn’t happen because AA agents didn’t let us board the flight

I liked nothing about this flight nor the incredible lack of service and communication on this flight from the Captain to every staff member. Arrogant, entitled and lacking any kind of basic customer service

Everything should be better, terrible flight and airport service. Delayed for 6 hours, flying around for 1 hr, and keeping us on a plane for another 2,5 -3hrs.

The plane was dirty. It appeared that Air Canada did not know vacuum cleaners had been invented. Second, the overhead bins were about 1/3 or 1/2 the size of "normal" bins. That was a problem. The worst was disembarking in the weather in Montreal. I have cold agglutinin disease. That means my red blood cells clump together and then are destroyed when exposed, even by breathing to cold air. A few seconds of exposure can be dangerous. I am now experiencing extreme fatigue caused by the anemia from that experience. I should have had more assistance descending a narrow ramp and then traversing, even if only a few feet, of icy pavement. The blowing snow penetrated my facial covering and has caused problems.

Good airport. Good entertainment on the big flight. Did not have a good way to prop up or mount my phone/ipad

I booked my flight ni November and was placed on standby? How does this happen. Flight was 1 1/2 hours late departure plane was switched to a smaller plane easy to tell this is a government run company they don’t care about anyone

Boarding was a disaster one person checking in 200 people took 25 min to check in zone 1&2.

Old, noisy plane, bad coffee, delayed. Flight attendant was very nice.

Boarding could be improved, no need to wait after a previous group is completed

We boarded 1.5 hours late. Long wait for the bags when we got to Mexico City. Long wait to get on plane with people mover truck. Friendly staff. They answered all questions as best the could. Such a long, long walk from the plane to customs. Thank you, Michael A. Burris Cambridge, Massachusetts USA

Delayed in Fort Lauderdale 3 hours , gave us $15 coupon for meals at 20:50, when most of the restuarant closed at 21:00.

Your crew is a representation of your Standards and Values. The crew from Seattle to LAX, was very disappointing. The crew was more interested in hanging out at the lobby area. Talking, laughing loudly and eating all the snacks. They did not do regular rounds to see if customers needed anything. This was a huge disappointment. I will no longer be flying with your airlines moving forward.

The senior flight attendant was engaging, funny and made everyone feel at ease. She is an asset to your team.

Terrible-extreme delay with very little communication, plane was overfull, luggage was returned on baggage claim in filthy condition.

Needs legroom for tall people. Needs to offer a glass of water.

Seats are very uncomfortable pls make your seats comfortable pls pls pls

They changed our departure time 6 times before I even reached the airport. Delayed, Ontime, Delayed Back on time, Then Delayed. We finally boarded the plane and then we had to sit on the runway for over an hour only to be told they were taking us back to the gate for an additional 2 hour delay. Lack of communication and a complete waste of time! Never again!

Non-professional acting crew, Very uncomfortable seats…!! Very bad pricing with all the add-ons for seat choice, luggage fees, etc….soon you’ll charge extra for oxygen. The ticket price means Nothing because in the end, the actual amount i paid, i could have and will in the future continue to fly on a real airline…

I was surprised by a mandatory bag charge when I checked in at the airport. "Carry-on" wasn't an option eventhough all that I had was a small pilot case. I paid $79 so my bag could fly with me.

The flight took an extra 30 min to take off because we were waiting for crew to board then it took another 30 min to get off the plane because there was no parking. Just overall ridiculous also please add a head rest my neck was gonna snap off thanks.

I was traveling with my son and it was our first time with spirit so I didn’t realize our seats weren’t assigned. They scrambled and gave us seats next to each other. Also My son got sick on the plane and they really took care of him. Super family friendly crew and experience!

Book cheap flights from Detroit to South America

Recent round-trip flight deals

4/29Tue
1 stopSpirit Airlines
8h 07mDTW-CTG
5/14Wed
2 stopsSpirit Airlines
10h 06mCTG-DTW
$228
4/29Tue
2 stopsSpirit Airlines
23h 20mDTW-CTG
5/14Wed
2 stopsSpirit Airlines
10h 06mCTG-DTW
$230
4/28Mon
2 stopsLATAM Airlines
16h 48mDTW-MDE
5/19Mon
2 stopsLATAM Airlines
16h 31mMDE-DTW
$569
5/25Sun
2 stopsAmerican Airlines
21h 02mDTW-CLO
6/16Mon
2 stopsAmerican Airlines
13h 17mCLO-DTW
$581
5/29Thu
2 stopsDelta
11h 39mDTW-CLO
6/10Tue
2 stopsDelta
13h 23mCLO-DTW
$582
5/11Sun
1 stopAmerican Airlines
8h 17mDTW-CLO
6/9Mon
1 stopAmerican Airlines
8h 35mCLO-DTW
$587
5/2Fri
2 stopsDelta
12h 23mDTW-CLO
5/15Thu
2 stopsDelta
15h 11mCLO-DTW
$592
5/6Tue
1 stopAir Canada
19h 35mDTW-BOG
7/30Wed
1 stopAir Canada
10h 01mBOG-DTW
$620
5/6Tue
2 stopsAir Canada
18h 00mDTW-BOG
7/31Thu
2 stopsAir Canada
24h 21mBOG-DTW
$626
5/3Sat
2 stopsLATAM Airlines
11h 39mDTW-CLO
5/14Wed
2 stopsLATAM Airlines
18h 07mCLO-DTW
$631

Search by stops

Search by airline

Search by price

Recent one-way flight deals

5/13Tue
2 stopsSpirit Airlines
22h 16mDTW-CTG
$84
5/13Tue
1 stopSpirit Airlines
16h 43mDTW-CTG
$88
6/13Fri
2 stopsAir Canada
21h 08mDTW-MDE
$335
4/19Sat
2 stopsAmerican Airlines
14h 48mDTW-MDE
$365
5/10Sat
1 stopAmerican Airlines
8h 17mDTW-CLO
$385
5/22Thu
1 stopDelta
8h 32mDTW-UIO
$473
6/3Tue
2 stopsAir Canada
29h 20mDTW-SDU
$537
3/4Tue
1 stopDelta
9h 22mDTW-BOG
$583
3/13Thu
2 stopsLATAM Airlines
18h 42mDTW-SDU
$796
3/5Wed
2 stopsLATAM Airlines
30h 22mDTW-AEP
$868

Search by stops

Search by airline

Search by price

Last minute flights from Detroit to South America

Last minute flight, train and bus deals

2/22Sat
multi-stopSpirit Airlines
15h 36mDTW-CTG
3/20Thu
multi-stopSpirit Airlines
9h 12mCTG-DTW
$407
2/22Sat
multi-stopSpirit Airlines
15h 36mDTW-CTG
3/20Thu
multi-stopSpirit Airlines
18h 13mCTG-DTW
$429
2/25Tue
multi-stop
26h 40mDTW-MDE
4/23Wed
multi-stop
18h 02mMDE-DTW
$465
2/24Mon
multi-stopDelta
10h 55mDTW-MDE
4/22Tue
multi-stopDelta
11h 46mMDE-DTW
$924
2/23Sun
multi-stopAmerican Airlines
8h 20mDTW-MDE
3/13Thu
multi-stopAmerican Airlines
16h 12mMDE-DTW
$933
2/23Sun
multi-stopDelta
12h 07mDTW-MDE
4/24Thu
multi-stopDelta
11h 04mMDE-DTW
$934
2/23Sun
multi-stopAmerican Airlines
8h 20mDTW-MDE
3/13Thu
multi-stopAmerican Airlines
15h 14mMDE-DTW
$937
2/23Sun
multi-stopAir Canada
12h 15mDTW-GRU
2/25Tue
multi-stopAir Canada
24h 06mGRU-DTW
$1,080
2/21Fri
multi-stopLATAM Airlines
13h 30mDTW-UIO
3/2Sun
multi-stopLATAM Airlines
23h 52mUIO-DTW
$1,308
2/23Sun
multi-stopLATAM Airlines
46h 28mDTW-AEP
2/25Tue
multi-stopLATAM Airlines
25h 44mAEP-DTW
$2,088

Search by stops

Search by airline

Search by price

Everything you need to know for your flight to South America

Information on your arrival and departure airports

Not what you’re looking for? Find thousands of other hotels, flights, car rentals and package deals with KAYAK.