$129 Find Cheap Flights from Detroit to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Detroit to South America departing on 5/25. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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Best South America Flight Deals from Detroit

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours

Lima
Lima2 stops$546
Bogotá
Bogotá1 stop$401
Sao Paulo
Sao Paulo3 stops$610
Cartagena
Cartagena1 stop$298
Santiago
Santiago2 stops$687
Quito
Quito2 stops$575
Cali
Cali2 stops$477
Guayaquil
Guayaquil2 stops$575
Cusco
Cusco3 stops$891
Montevideo
Montevideo2 stops$1,276

Cheap Flights from Detroit to South America

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Detroit to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.

Recent round-trip flight deals from Detroit to South America

Recommended round-trip deals departing in the coming months from the most popular airlines that fly from Detroit to South America.
Discover the best prices for you by selecting your travel dates on KAYAK.
Choose your dates
Spirit Airlines Logo
6:00 am - 12:10 pmDTW-CTG
7h 10m1 stop
Spirit Airlines Logo
1:15 pm - 11:45 pmCTG-DTW
9h 30m1 stop
$298Spirit Airlines
Find Deal
Sun, Jun 8 - Thu, Jun 12
Spirit Airlines Logo
6:00 am - 12:10 pmDTW-CTG
7h 10m1 stop
Spirit Airlines Logo
1:15 pm - 7:30 amCTG-DTW
17h 15m2 stops
$302Spirit Airlines
Find Deal
Sun, Jun 8 - Thu, Jun 12
American Airlines Logo
6:51 am - 10:30 pmDTW-BOG
16h 39m1 stop
American Airlines Logo
6:30 am - 11:08 pmBOG-DTW
15h 38m1 stop
$413American Airlines
Find Deal
Thu, May 8 - Wed, May 21
American Airlines Logo
5:00 am - 10:30 pmDTW-BOG
18h 30m1 stop
American Airlines Logo
6:30 am - 11:18 pmBOG-DTW
15h 48m2 stops
$417American Airlines
Find Deal
Thu, May 15 - Mon, May 19
Delta Logo
8:30 pm - 2:03 pmDTW-CLO
18h 33m2 stops
Delta Logo
10:49 pm - 11:13 amCLO-DTW
11h 24m2 stops
$612Delta
Find Deal
Fri, Jun 27 - Sun, Jul 13
LATAM Airlines Logo
6:30 am - 11:16 pmDTW-CLO
17h 46m2 stops
LATAM Airlines Logo
1:27 am - 8:32 pmCLO-DTW
18h 05m2 stops
$622LATAM Airlines
Find Deal
Sat, Oct 11 - Fri, Oct 24
LATAM Airlines Logo
8:30 pm - 6:39 pmDTW-MDE
23h 09m2 stops
LATAM Airlines Logo
8:36 pm - 3:54 pmMDE-DTW
18h 18m2 stops
$624LATAM Airlines
Find Deal
Fri, Jun 20 - Mon, Jun 30
Delta Logo
8:40 am - 11:59 pmDTW-CLO
16h 19m2 stops
Delta Logo
7:42 am - 9:50 pmCLO-DTW
13h 08m2 stops
$650Delta
Find Deal
Thu, Jul 3 - Thu, Jul 17
Air Canada Logo
9:55 am - 7:13 amDTW-MDE
22h 18m2 stops
Air Canada Logo
6:13 am - 9:25 pmMDE-DTW
14h 12m2 stops
$709Air Canada
Find Deal
Sat, May 3 - Thu, May 8
Air Canada Logo
4:20 pm - 7:14 amDTW-CTG
15h 54m2 stops
Air Canada Logo
5:43 am - 9:29 pmCTG-DTW
14h 46m2 stops
$716Air Canada
Find Deal
Fri, Oct 17 - Mon, Oct 20

KAYAK's insights & trends for Detroit to South America flights

Get data-powered insights and trends into flights from Detroit to South America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest time of day to fly to South America?

The average price for all round-trip flights from Detroit Metropolitan Wayne County Airport to South America depending on the time of departure, clicked by users on KAYAK in the last 2 weeks.
The cheapest time of day to fly to South America is generally in the morning, when round-trip flights cost $923 on average. Morning departures are around 3% cheaper than evening flights, on average. The most expensive time of day to fly to South America is generally in the evening, which is peak travel time and where the average cost of a ticket is $954.

What is the cheapest month to fly from Detroit Metropolitan Wayne County Airport to South America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Detroit Metropolitan Wayne County Airport to South America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.
The cheapest month for flights from Detroit Metropolitan Wayne County Airport to South America is February, when tickets cost $807 (return) on average. On the other hand, the most expensive months are December and May, when the average cost of round-trip tickets is $1,258 and $1,177 respectively.

What’s the cheapest day of the week to fly from Detroit to South America?

The average price of all round-trip flights from Detroit Metropolitan Wayne County Airport to South America clicked on KAYAK for each day over the last 12 months.
If you are looking for a flight deal from Detroit to South America, look for departures on Tuesdays and avoid leaving on a Saturday, as it's usually the priciest day. When flying back from South America, Wednesday is the cheapest day to fly and Friday is the most expensive.

How far in advance should I book a flight from Detroit Metropolitan Wayne County Airport to South America?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Detroit Metropolitan Wayne County Airport to South America, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.
To get a below average price on the flight from Detroit Metropolitan Wayne County Airport to South America, you should book around 7 weeks before departure. For the absolute cheapest price, our data suggests you should book 23 weeks before departure.

Good to know

Low season

September

High season

December

Cheapest flight

$129
Best time to beat the crowds with an average 6% drop in price.
Most popular time to fly with an average 28% increase in price.
Flight from Detroit to Cartagena

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Detroit to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Detroit to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Detroit to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Detroit to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Detroit to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Detroit to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Detroit to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Detroit to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Top 5 airlines serving from Detroit to South America

Need help choosing which airline to fly with from Detroit to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
DeltaOverall score based on 7920 reviews
8.2Boarding
8.5Crew
7.9Comfort
7.3Food
7.9Entertainment
Airline reviews

Delta flight was on time, seats were comfortable, and crew was nice.

8.0 ExcellentAnonymous, Apr 2025LAX - DEN
Read more Delta reviews

Delta flight was on time, seats were comfortable, and crew was nice.

This had nothing to do with Delta… The flights were on time and flawless. The service was excellent. We purchased seats in (aisle/middle) comfort plus since this was a cross country flight. Unfortunately, the woman seated at the window was 300+ pounds and, as might be expected, covered up about a third of the middle seat also. there was absolutely nothing that Delta could have done about that… I just don’t know what the answer should be. If you purchase a seat, you should should be able to use the entire seat and not just the portion that someone else is not sitting/oozing in. Disappointing…there should be something that could be done….I'm just not sure what solution could be.

Delayed take-off. Very small plane so very scary with lots of bumps during the flight. Would never fly Delta on short flights in small 80 seaters plane again! Felt relieved when landed.

The worst part was I was NOT allowed in the lounge even though I was holding a first class ticket and have a premium American Express card. I have flown Business or First Class with many airlines. Delta is the ONLY one who does not extend this courtesy to anyone except people who hold the very expensive American Express card. As a result, I won’t fly Delta if I have any other choice.

It was an overnight flight and I desperately needed coffee before we landed, but Delta does only one beverage service, and that is shortly after takeoff, not before landing at 5 am.

A little bumpy ride . No food was being provided due the the turbulence. That was ok it was a short flight to my standards.

Simply outstanding. Their new lounge for Delta One customers is a cut above the rest.

The Dekta Rep that checked us in was great. She's very personable, pleasant, and can tell she enjoys her job.

After a 5 hour delay waiting at the gate (3 delays adding up) with no clear reason provided, we finally boarded flew 3/4 of the way to Toronto then were turned back to New York. As we neared New York, the pilot declared that it was his fault, something to do with timing and him not being allowed into the country???? How could the airline let his happen? They had hours to prepare and make sure they had a crew available for the flight! We ended up in Toronto a day late with no sleep.

The plane was old with small storage areas that had problems closing/latching and not enough storage for everyone, and worn, damaged seats. Service was great but feel a little unsafe on such well used planes.

It was good, however the airplane was really cold. We received snacks and the crew was friendly.

Delta has an outstanding service. They are courteous and punctual most of the time. The flight departed a half hour late but we arrived 15 minutes early.

Although the flight is goof and the crew is good, the way the airline charges you for every service is ridiculous.

No entertainment but not expected. Unless you are referring to monitor that you can use. Then Al, was fine on all flights.

Friendly staff, It was the first flight out for our plane, so had to be deiced from the frost. Only delayed a few minutes,

Staff encountered friendly and helpful. Flight delayed 1 hour due to mechanical issue, but made it through Atlanta immkgration and security in plenty of time,

We boarded so late it caused us to miss time at Foz. No real information was provided to the passengers waiting.

reliable, relatively relaxed, helpful and kind staff and clean airplanes. No need for more.

Only complaint is that the entertainment system wasn’t working on our seats and some others.

Very slow boarding, 1 hour late - uncomfortable chairs and crew barely speaking english even at the airport!

First world problems, but still… We were seated in first class and asked for a cocktail on a very short, 50 minute flight. After our drink order was taken, a half hour went by, and we noticed that every other person in the small plane had been served except for us. We got up to ask about it, the drinks finally came, then were taken away three minutes later since the flight was so short. Really strange situation, on the other hand, we were in Utah.

We missed our flight. The boarding pass had the wrong gate and by the time we received the text from Kayak, our flight was already gone. I’ll never use Kayak again and will go direct to the airlines in the future.

Boarding took forever, the plane was cramped and cold, and the seatbelt song came on constantly throughout the red eye flight with a loud pre-recorded message playing each time

Cabin felt crammed Snacks are lame But crew was super efficient getting us out on time despite delay

Took off on time and successfully avoided weather that looked to be a problem along the way

There were five broken seats on the plane. The crew was very rude in telling people they had to get off the plane and get a flight the next day. No call for volunteers, but telling people they had to get off. One woman was flying with her elderly mother and daughter and was told she had to leave or all three had to leave. Fortunately, a volunteer offered to stay. The situation was handled poorly.

The flight to Tokyo AA61 took off about two hours late, but then had to turn back. By that time the crew had to be replaced. Then they kept promising to take off in an hour, then in 3, then switch to the next day.

British Airways staff are very polite and willing to help.

Any sort of gluten free snack option would be nice

They lost my luggage and it didn’t get delivered until the next day.

Short flight so no food or entertainment. Good landing at SFO and on time. We were told no carryon luggage yet lots of people were puting bags in overhead compartments. The rules need to be made more clear. I was on the first leg of an international flight and this is the first time I could not have carryon luggage.

This flight didn't happen for me because of overbooking.

My flight was overbooked and they would not let me board. I had to book another flight and pay the full amount of that flight. I did not get any help at all from Air Canada or United Airlines.

Comfortable seats and movies entertainment available. Better experience than the flight from Toronto to Denver.

Poor air traffic controller staffing led to a 50%reduction on flights so we got to wait 4 hrs for our flight! Very disorganized at the gate Poor communication with customers

It was delayed by almost 90 minutes and that messed up our plans but it was beyond UA’s control that is what we heard

Terrible experience, flight was delayed both ways. Limited compensation for the 5+ hour delay. Will not be flying Air Canada Rouge, and don’t recommend you do either.

The boarding was relatively quick, the crew welcoming and flight uneventful. The omission of meals on all airlines is unacceptable especially when the flight is during a mealtime such as this one, (lunchtime), is unacceptable.

Everything was simple and easy. The lady at the gate was super friendly, I wish I had her name to share. She's a little older, dark-haired. You can tell she likes her job and would be a great influence on any young people training with her.

Everything was made rather simple, so I appreciate that. All the people I dealt with from entering the airport in Jacksonville to my lonnnnnnng walk to my next gate in Chicago were excellent and very helpful.

terrible service, no room for a dog underfoot, a broken chair that is impossible to sit on and all this costs a lot of money

Easy boarding. Met expectations for a 2-3 hour flight. Early arrival at DFW caused a 39 minute delay on the tarmac in getting to our gate. 😏 overall, good flight.

Very efficient process and boarding, seats felt standard. Flight conditions from take off to landing had been very smooth. Alcohol on the menu however was not available… Will fly Spirit in the future for the price, you can’t really complain if you fly light.

It’s what we expected from Spirit..reasonable cost, good for a 2-3 hour flight. Disappointed that we had a 2 hour delay in departure from DFW for a maintenance issue, but the pilot handled it well once we were outbound on a different Airbus.

Worst airline ever! The guy weighing my bag had his foot on the metal plate and when I called him out on it, I got this stupid little smirk. La is a scam and so is Spirit Airlines. All the flight attendants looked like they hated our flight just as much as we did.

My experience with Spirit went pretty much as expected. It's a no frills airline, and you get what you pay for. I don't require much, so I was grateful to have an inexpensive way to travel. It is sad to me that the gate agents and flight crew don't smile much or seem very friendly or helpful. They are competent and efficient, and that's really all I need.

My experience was okay. The flight did not offer even water without a fee. Also had to pay extra for my carry on, as I was told I had to check my bag, even though it said I had the option to carry on a bag when booking. This costed me an extra $100. Would likely not fly with Spirit again.

The flight was rescheduled several times without a reason for the schedule changes. I had to be in New Orleans at a certain time and it was just easier to drive at a certain point. I don’t know if the flight ever left. This is my first experience with Spirit Airlines and is also the last.

It was fast but uncomfortable seats. Had to pay a bit extra not sure why? Maybe in selection of all my 4 tix together ? Just knew I had a balance before getting boarding pass online when departing from satx ? And flight was delayed..

In a word, it was horrible. The flight crew timed out and this, apparently was not accounted for by management. This meant that our 10:15 departure turned into a 1:30am departure the next DAY!!! And some brainchild decided to email us 12$ food vouchers set to expire the 9th, but they sent them after EVERY VENDOR WAS CLOSED in the Miami airport and obviously none would be open in New Orleans. I found this to be another sterling example of, at best, shitty management…at worst an absolute lack of empathy for your customers. Triplt Pro: Check-in may be avail for NK222 dep MIA 4/8/2025 10:16pm. Conf#RGSUMI. https://tripit.com/t/. e106fd644e0a; Today 6:16 PM TripIt Pro: NK222 ON TIME. MIA dep 10:16pm term C, gate F5. MSY arr 11:38pm. Today 8:59 PM Tript Pro: NK222 DELAYED. MIA dep 1:00am term C, gate F5. MSY arr 2:18am. Alternate flights: https:// www.tripit.com/t/b2903869f438 Triplt Pro: NK222 PULLED IN. MIA dep 12:30am term C, gate F5. MSY arr 1:48am. Alternate flights: https:/// www.tripit.com/t/834d176c630b Tript Pro: NK222 DELAYED. MIA dep 1:00am term C, gate F5. MSY arr 1:48am. Alternate flights: https:/// www.tripit.com/t/0441e41a9dd3 Triplt Pro: NK222 PULLED IN. MIA dep 12:30am term C, gate F5. MSY arr 1:48am. Alternate flights: https:// www.tripit.com/t/92ac2157ef54 The sender is not in your contact

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