DSM - SFO

$95 Find Cheap Flights from Des Moines to San Francisco

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to San Francisco departing on 2/14. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to San Francisco, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to San Francisco, as well as popular online travel agencies
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Cheap Flight Deals from Des Moines to San Francisco (DSM-SFO)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to San Francisco that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.

Recent round-trip flight deals from Des Moines to San Francisco

Recommended round-trip deals departing in the coming months from the most popular airlines that fly from Des Moines to San Francisco.
Discover the best prices and deals for you by selecting your travel dates.
Choose your dates
7:27 pm - 12:33 amDSM-SFO
7h 06m1 stop
6:00 am - 6:30 pmSFO-DSM
10h 30m1 stop
$130Frontier
Find Deal
Wed, Apr 23 - Mon, May 5
7:20 pm - 12:31 amDSM-SFO
7h 11m1 stop
6:00 am - 6:30 pmSFO-DSM
10h 30m1 stop
$150Frontier
Find Deal
Fri, May 2 - Mon, May 5
10:22 am - 6:49 pmDSM-SFO
10h 27m1 stop
10:45 pm - 9:41 amSFO-DSM
8h 56m1 stop
$351Delta
Find Deal
Tue, Mar 18 - Tue, Mar 25
12:25 pm - 7:12 pmDSM-SFO
8h 47m1 stop
12:40 am - 11:31 amSFO-DSM
8h 51m1 stop
$354Delta
Find Deal
Sat, Feb 15 - Mon, Feb 17
2:15 pm - 9:35 pmDSM-SFO
9h 20m2 stops
6:05 am - 3:20 pmSFO-DSM
7h 15m1 stop
$356Southwest
Find Deal
Wed, Feb 19 - Wed, Feb 26
2:15 pm - 9:35 pmDSM-SFO
9h 20m2 stops
6:05 am - 7:00 pmSFO-DSM
10h 55m2 stops
$361Southwest
Find Deal
Wed, Feb 19 - Wed, Feb 26
2:06 pm - 9:12 pmDSM-SFO
9h 06m1 stop
10:11 am - 10:08 pmSFO-DSM
9h 57m2 stops
$362American Airlines
Find Deal
Tue, Feb 4 - Tue, Feb 11
12:15 pm - 11:39 pmDSM-SFO
13h 24m1 stop
5:15 am - 10:28 pmSFO-DSM
15h 13m1 stop
$385American Airlines
Find Deal
Thu, Feb 27 - Tue, Mar 4
5:45 am - 9:36 amDSM-SFO
5h 51m1 stop
6:42 am - 4:14 pmSFO-DSM
7h 32m1 stop
$408United Airlines
Find Deal
Wed, Apr 2 - Sun, Apr 6
6:00 am - 9:45 amDSM-SFO
5h 45m1 stop
5:05 am - 12:54 pmSFO-DSM
5h 49m1 stop
$443United Airlines
Find Deal
Thu, May 22 - Mon, May 26

Flights from Des Moines to San Francisco - Travel Insights & Trends

Get data-powered insights and trends into flights from Des Moines to San Francisco to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Des Moines to San Francisco?

The average price of all round-trip flights from Des Moines to San Francisco clicked on KAYAK for each day over the last 12 months.
Your flight ticket price will generally be cheaper if you fly to San Francisco on a Wednesday and more expensive on a Sunday. On your return trip to Des Moines, you should consider flying back on a Wednesday, and avoid Sundays for better deals.

What is the cheapest month to fly from Des Moines to San Francisco?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Des Moines to San Francisco, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.
The cheapest month for flights from Des Moines to San Francisco is September, where tickets cost $350 (return) on average. On the other hand, the most expensive months are January and June, where the average cost of round-trip tickets is $605 and $528 respectively.

How far in advance should I book a flight from Des Moines to San Francisco?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Des Moines to San Francisco, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.
To get a below average price on the flight from Des Moines to San Francisco, you should book around 3 weeks before departure. For the absolute cheapest price, our data suggests you should book 14 weeks before departure.

Good to know

Low season

January

High season

June

Cheapest flight

$95
Best time to beat the crowds but there is an average 30% increase in price.
Most popular time to fly with an average 13% increase in price.
Flight from Des Moines to San Francisco

When to book flights from Des Moines to San Francisco

Are your dates flexible? Find out the best times to travel from Des Moines to San Francisco based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Des Moines to San Francisco

  • What is the cheapest flight from Des Moines to San Francisco?

    In the last 3 days, the lowest price for a flight from Des Moines to San Francisco was $95 for a one-way ticket and $130 for a round-trip.

  • Do I need a passport to fly between Des Moines and San Francisco?

    A passport is not required to fly from Des Moines to San Francisco.

  • Which airports will I be using when flying from Des Moines to San Francisco?

    Des Moines and San Francisco are both served by 1 main airport. You will leave Des Moines from Des Moines and will be arriving at San Francisco.

  • Which aircraft models fly most regularly from Des Moines to San Francisco?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Des Moines to San Francisco?

    oneworld, SkyTeam, and Star Alliance are the airline alliances operating flights between Des Moines and San Francisco, with SkyTeam being the most commonly used for this route.

  • What is the most popular layover when flying to San Francisco from Des Moines?

    Denver is the most popular layover city among KAYAK users traveling from Des Moines to San Francisco.

  • Which is the best airline for flights from Des Moines to San Francisco, Southwest or Delta?

    The two airlines most popular with KAYAK users for flights from Des Moines to San Francisco are Southwest and Delta. With an average price for the route of $439 and an overall rating of 8.1, Southwest is the most popular choice. Delta is also a great choice for the route, with an average price of $486 and an overall rating of 8.0.

  • How does KAYAK find such low prices on flights from Des Moines to San Francisco?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to San Francisco.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to San Francisco?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Francisco from Des Moines is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to San Francisco?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Francisco with an airline and back to Des Moines with another airline. Booking your flights between Des Moines and SFO can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to San Francisco?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Francisco from Des Moines up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Top 5 airlines serving from Des Moines to San Francisco

 
See real verified KAYAK customer reviews for airlines flying from Des Moines to San Francisco. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Des Moines to San Francisco? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.1
SouthwestOverall score based on 4662 reviews
8.1Comfort
7.2Food
8.7Crew
7.7Entertainment
8.2Boarding
Airline reviews

Fine, but how to board on SW versus othrr airlines, is just lame. Goood staff though and all was solid otherwise.

10.0 ExcellentAnonymous, Dec 2024AUS - OAK
Read more Southwest reviews

Fine, but how to board on SW versus othrr airlines, is just lame. Goood staff though and all was solid otherwise.

Was as expected. Crowed planes. Too many carryons delaying takeoff. But the ride only took an hour and saved me a lot of time SFO is a not a great airport.

Was as expected. Crowed planes. Too many carryons delaying takeoff. But the ride only took an hour and saved me a lot of time SFO is a hell hole of an airport. It is the new LaGuardia. Everything Cobbled together. Security gates closed. Terri directional signage

I will be flying again Southwest Airlines. Friendly crew, comfortable and affordable.

The plane arrived 25 minutes late, and the Wi-Fi was slower than it usually is.

Forget beverage, they didn't even have water for half the passangers?

Can not wait for seating change to reduce the amount of pre boards - it’s disheartening the abuse. And then then deplaning

The crew was nice. Boarding sucked. Instead of loading from the back to the front people just sat wherever and you had to wait for them to move to get to a seat. And the flight was 25 minutes delayed.

I boarded last because of my boarding assignment and was given a middle seat at the back of the plane. I’m 6”1” so it was really tight. I wish I just had a seat assignment instead of a general boarding group. My bag was way at the front and my seat at the back. Was never offered a beverage and had no room to move.

The open seating makes passengers boarding ahead of you think they also have the right to the empty middle seat. Trumper next to me refused to move her laptop bag from my leg area. I did not make a fuss since it was a short flight.

If I pay extra for "comfort+" I expect leg room where I can stretch my legs. I was seated with an attendant's seat blocking my feet. Knee space was fine but my feet had less room than the non-"comfort+" seats. Also, don't go cheap on food when you have flights of 3+ hours. It's insulting.

Only one side of the heafphone jack work. Crew was friendly and helpful.

Great. Flight departed early and arrived early. Deplaning and baggage claim ww were quick.

They separated our seats and moved us to the back of the plane. Hundreds of dollars and thousands of miles used and this was my platinum member experience.

AC barely worked on a 50 minute flight. It was very warm the whole flight. Flight was very bumpy and hard landing.

Got on the plane and then needed to deboard the plane because they didn’t have any pilots?

The flight was canceled two hours before departure, it took over five hours to rebook us on another flight.

Rough day of travel all the way around. Wrong info given to us multiple times and mistakes in their booking making our trip 10 hours longer than planned. I’m bummed because I fly Delta all the time and love them. Mistakes happen. Just bummed that this was a rare trip our whole family was traveling together.

Meh. A late flight meant I missed my connections, and a 2pm LAX arrival turned into gettin in after midnight.

It was good until there was a 3 hour delay because there was not any pilots to fly the plane.

Awful. Worst airline I have ever been on. Crew were among the rudest people I have ever dealt with. United staff members were rude and disrespectful. My flight was delayed, causing me to miss a connecting flight. I understand things happen, but when staff start lying about what actually happened, that is when I have an issue. Just be honest, really it isn’t that hard. I’m being very honest with this review and I don’t find this difficult what so ever. In fact, because of United Airlines, my Christmas holiday was off to a really rocky start. As someone who has traveled across the world, it has only been United that I have had a truly awful experience.

Good flight. On time. Boarding and seating was easy. Crew were really friendly, yet professional. Bathroom (by cockpit) was small but serviceable. Some the seats were showing some notable wear & tear, but were comfy. Very happy UA customer. TY! 🤛🏽💗

We were delayed 3x and because I didn’t purchase my tickets directly from United Airlines I was told I Have to take care of it myself so I called Underpricer and they helped me but before I changed my flights I took the risk of sticking by what my tickets were and was lucky to have gotten on the original all flight with only 15 mins before take off. not sure if I will do this again

Everything good until we waited for jet bridge at SFO. Then pilot gets on speaker & said it won’t reach plane- too short, need to go to different gate. Then 5 min later, adjusted plane/jetbridge & all ok?!?

We had to wait almost an hour for the wheelchair porter to be ready to pick up my mother. And when she arrived in Newark airport the porter was not there and she started walking with her cane and her poor mobility. When the Newark porter found her they didn't want to transfer her bags to the wheelchair for her.

Great onboard crew. Boarding was a zoo, I got in line before pre boarding in Group 2, still had my bag force checked. WiFi was glitchy all flight. Seat and bathroom are both tiny unless you pay $$$ for first class.

Cabin was pitch black, even during meal service. The reading lights for seat 2E/F did not work, and seat 2E did not recline.

Was realllly smooth. It was delayed but we were well informed.

Delayed by 2.5hrs any longer and they would’ve had to honour their own policy for breaking their own rules and regs. Not cool, especially when I have an infant child that needs to stay on a routine and they get schedules.

To san Francisco it was ok. From sf to Manila it was horrible

The service and food needs to improve to catch up with other international flights

Would have been good to have a meal since it was a 5.5 hour flight

We boarded after several delays due to mechanical failure and a gate change. The seat cushion in the exit row was very compressed and offered no cushion, making the four-hour journey reasonably uncomfortable. The WiFi worked for a few people, but for most, it did not, and you cannot get entertainment unless you can connect—American Airlines flights do not have seatback screens, and you must use your mobile phone.

Terrible. Internet/kiosk glitch prevented baggage checkin. Line at ticket co in Ter was under serviced and did not move. Agents did not call for flight but rather allowed time to pass. Then told each person as they reached the front if line that it was too late to check bags so they’d have to rebook flights. At least 15 people missed the flight as a result of this incompetence.

AA is always pretty solid. Was on time all the way around today so can’t complain!

My boarding pass wouldn't pull up in the app very easily and had to really dig through my email. That caused a delay in TSA..

It was exactly what I expected, actually arriving sooner than scheduled.

RE Food: Wish there was a choice for No Rating. Flew from Honolulu to Los Angeles on a Red-Eye flight (11:00 pm to 7:30 am). Other than a package of cookies with a beverage choice offered soon after take-off, and a beverage choice shortly before landing, no other food choices were offered. Everyone slept or rested for most of the trip. Nothing to rate. RE Entertainment: Everyone was sleeping most of the flight. Only saw one passenger watch about 30 minutes of entertainment on his iPad. I never attempted to access any entertainment options.

Baby cried a lot. Nothing anyone could do about it. Just part of flying.

The boarding process was such a chaos with everyone crowding at the gates. There was no structure. The onboard crew were fantastic and very good.

Very easy with the app to board and staff skills

After waiting several minutes to be acknowledged by 3 employees on their phones, was told we had missed our flight because the doors were closed at that literal moment. Had they given any actual service or help while we were standing there we would have been on with time to spare. More than 10 people were turned away in this fashion claiming there was no way they could let us on the plane, even though it was still sitting connected to the terminal. After the desk agents let us know they didn't care about the situation we were forced to pay more than twice the price of our original tickets as no credits were given for the price of the "missed" flight. And the icing on the cake was after being treated poorly, fleeced for another few hundred dollars for new tickets? We waited on the next plane for 25 minutes passed the "doors closed" time, letting almost an extra dozen passengers on board. You're company has lazy, disinterested employees and your lack of any real help will ensure this was the first and last time we fly Frontier. Awful.

My experience with the phoenix airport was terrible, the personnel lay the ticket counter charged me for a carry on that fit in the carry on size box, and the two women I spoke with were terribly rude and not willing to help.,,, there was one lady “candy” on the flight crew that was amazing and is the only reason I stayed on the flight at all, because the other stewards helping people to get seated on the plane were terrible

I loked walking out on the tarmac to board and no first class. I didn't like that they have no snacks or onboard wifi to bide your time.

The plane was clean, the crew was friendly and helpful. It’s a low cost airline so there was no food, drinks or in flight entertainment but we didn’t expect any of these things. In the room for improvement department, they should install USB ports in seats to charge mobile devices.

The seats were extremely hard and uncomfortable, even for a budget airline.

The seats were extremely hard and uncomfortable. It was disappointing even for a budget airline.

Charging $74 for one checked bag is outrageous. I will never fly Frontier again.

Boarding was very well executed. Got my bag right away.

I was surprised that all baggage, including carry on, were charged. Each additional bag went up in cost. Really disappointed in the additional costs.

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