DSM - SFO

$110 Find Cheap Flights from Des Moines to San Francisco - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to San Francisco departing on 9/20. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$190
Typical prices: $366-$407
Multiple Airlines
Mon 9/21Tue 9/29
DSM - SFO • 1 stop
Cheapest one-way
$110
Typical prices: $196-$318
Multiple Airlines
Sun 9/20
DSM - SFO • 1 stop
Nonstop flights
Not available
There are currently no direct flights between Des Moines and San Francisco. You'll need at least 1 connection.
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Top layover airports
Dallas (DFW)
Cheapest • Avg $403 (round-trip)
Phoenix (PHX)
Shortest trip • 6h 30m (one-way)
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When to book
5 weeks
in advance
Our data shows that travelers who book at least 5 weeks in advance save around 29% compared to booking last minute.
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When to travel
February
Cheapest • 19% price drop
September
Most popular
Good to know
Good to know
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We hope you love your trip to San Francisco!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Des Moines to San Francisco (DSM-SFO)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to San Francisco that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to San Francisco

Mon, Sep 21 - Tue, Sep 29
Multiple Airlines Logo
9:31 pm - 8:14 am
DSM
-
SFO
12h 43m
1 stop
Multiple Airlines Logo
3:15 pm - 1:52 pm
SFO
-
DSM
20h 37m
1 stop
$190Multiple Airlines
Mon, Sep 21 - Thu, Oct 1
Multiple Airlines Logo
9:31 pm - 2:29 pm
DSM
-
SFO
18h 58m
1 stop
Multiple Airlines Logo
10:24 pm - 10:57 am
SFO
-
DSM
10h 33m
1 stop
$193Multiple Airlines
Fri, Sep 11 - Mon, Sep 14
Frontier Logo
8:30 pm - 12:14 am
DSM
-
SFO
5h 44m
1 stop
Frontier Logo
6:04 am - 7:33 pm
SFO
-
DSM
11h 29m
1 stop
$262Frontier
Mon, Sep 28 - Mon, Oct 5
Frontier Logo
8:30 pm - 12:14 am
DSM
-
SFO
5h 44m
1 stop
Frontier Logo
6:04 am - 7:33 pm
SFO
-
DSM
11h 29m
1 stop
$262Frontier
Sat, Sep 12 - Sat, Sep 19
American Airlines Logo
9:51 am - 3:01 pm
DSM
-
SFO
7h 10m
1 stop
American Airlines Logo
2:58 pm - 12:04 am
SFO
-
DSM
7h 06m
1 stop
$300American Airlines
Sat, Oct 3 - Tue, Oct 6
American Airlines Logo
7:05 am - 12:39 pm
DSM
-
SFO
7h 34m
1 stop
American Airlines Logo
12:41 pm - 11:07 pm
SFO
-
DSM
8h 26m
1 stop
$300American Airlines
Tue, Aug 18 - Fri, Aug 21
Delta Logo
2:54 pm - 11:58 pm
DSM
-
SFO
11h 04m
1 stop
Delta Logo
12:12 am - 10:18 am
SFO
-
DSM
8h 06m
1 stop
$300Delta
Tue, Aug 18 - Thu, Aug 27
Delta Logo
2:45 pm - 9:02 pm
DSM
-
SFO
8h 17m
1 stop
Delta Logo
10:00 pm - 10:43 am
SFO
-
DSM
10h 43m
1 stop
$300Delta
Sat, Sep 12 - Sat, Sep 19
Southwest Logo
5:30 am - 1:10 pm
DSM
-
SFO
9h 40m
1 stop
Southwest Logo
6:40 am - 2:10 pm
SFO
-
DSM
5h 30m
1 stop
$301Southwest
Wed, Jan 6 - Tue, Jan 12
Southwest Logo
6:25 pm - 10:00 pm
DSM
-
SFO
5h 35m
1 stop
Southwest Logo
1:25 pm - 8:40 pm
SFO
-
DSM
5h 15m
1 stop
$301Southwest
Booking Insights

KAYAK's insights & trends for Des Moines to San Francisco flights

Get data-powered insights and trends into flights from Des Moines to San Francisco to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Des Moines to San Francisco?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Des Moines to San Francisco departing in August.

Flight prices are below average for this route right now.

Flights to San Francisco from Des Moines usually cost between $365 and $553 in August.
The lowest price found in the past 5 days was $193 on Multiple Airlines (Aug 23-Aug 27).

What is the cheapest month to fly from Des Moines to San Francisco?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Des Moines to San Francisco, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Des Moines to San Francisco is February, where tickets cost $367 (return) on average. On the other hand, the most expensive months are June and July, where the average cost of round-trip tickets is $566 and $506 respectively.

How far in advance should I book a flight from Des Moines to San Francisco?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Des Moines to San Francisco, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Des Moines to San Francisco, you should book around 5 weeks before departure, which saves you about 29% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 16 weeks before departure.

Find deals

Good to know

Low season

February

Cheapest flight

$110
Best time to beat the crowds with an average 20% drop in price.
Most popular time to fly and prices are also 20% lower on average.
Flight from Des Moines to San Francisco

When to book flights from Des Moines to San Francisco

Are your dates flexible? Find out the best times to travel from Des Moines to San Francisco based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Des Moines to San Francisco

  • What is the cheapest flight from Des Moines to San Francisco?

    In the last 5 days, the lowest price for a flight from Des Moines to San Francisco was $110 for a one-way ticket and $190 for a round-trip.

  • Do I need a passport to fly between Des Moines and San Francisco?

    A passport is not required to fly from Des Moines to San Francisco.

  • Which airports will I be using when flying from Des Moines to San Francisco?

    Des Moines and San Francisco are both served by 1 main airport. You will leave Des Moines from Des Moines and will be arriving at San Francisco.

  • Which aircraft models fly most regularly from Des Moines to San Francisco?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Des Moines to San Francisco?

    SkyTeam, Star Alliance, and oneworld are the airline alliances operating flights between Des Moines and San Francisco, with SkyTeam being the most commonly used for this route.

  • What is the most popular layover when flying to San Francisco from Des Moines?

    Denver is the most popular layover city among KAYAK users traveling from Des Moines to San Francisco.

  • Which is the best airline for flights from Des Moines to San Francisco, Southwest or Delta?

    The two airlines most popular with KAYAK users for flights from Des Moines to San Francisco are Southwest and Delta. With an average price for the route of $489 and an overall rating of 8.0, Southwest is the most popular choice. Delta is also a great choice for the route, with an average price of $502 and an overall rating of 7.8.

  • How does KAYAK find such low prices on flights from Des Moines to San Francisco?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to San Francisco.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to San Francisco?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Francisco from Des Moines is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to San Francisco?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Francisco with an airline and back to Des Moines with another airline. Booking your flights between Des Moines and SFO can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to San Francisco?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Francisco from Des Moines up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Everything you need to know for your flight from Des Moines to San Francisco

Information on your arrival and departure airports

Des Moines (DSM)
San Francisco (SFO)