DSM - SAN

$158 Find Cheap Flights from Des Moines to San Diego

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to San Diego departing on 12/9. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to San Diego, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to San Diego, as well as popular online travel agencies
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Cheap Flight Deals from Des Moines to San Diego (DSM-SAN)

 
These are the cheapest deals for flights from Des Moines to San Diego currently on KAYAK along with options from the most popular airlines KAYAK users selected for this route. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.

Recent round-trip flight deals from Des Moines to San Diego

Recommended round-trip deals departing in the coming months from the most popular airlines that fly from Des Moines to San Diego.

Recent one-way flight deals from Des Moines to San Diego

Only flying one-way? Below are some of the best one-way flight deals from Des Moines to San Diego found on KAYAK recently.

Recent last minute flight deals from Des Moines to San Diego

Leaving soon but still want a bargain? Check out these latest deals for last minute flights from Des Moines to San Diego.

Recent direct flight deals from Des Moines to San Diego

The latest deals for direct flights from Des Moines to San Diego so you can sit back and relax without the need for a layover.

Cheap bus & train deals from Des Moines to San Diego

Find recent round-trip train or bus tickets from Des Moines to San Diego.

All round-trip flight deals to San Diego

The cheapest plane tickets to San Diego found on KAYAK recently.
Discover the best prices and deals for you by selecting your travel dates.
Choose your dates
5:07 pm - 12:38 pmDSM-SAN
21h 31m1 stop
6:25 am - 4:07 pmSAN-DSM
7h 42m1 stop
$158Frontier
Find Deal
Mon, Dec 9 - Mon, Dec 16
2:29 pm - 10:12 pmDSM-SAN
9h 43m1 stop
6:15 am - 10:02 pmSAN-DSM
13h 47m1 stop
Mon, Jan 6 - Fri, Jan 10
5:50 am - 12:50 pmDSM-SAN
9h 00m1 stop
6:15 am - 4:59 pmSAN-DSM
8h 44m1 stop
$334Delta
Find Deal
Tue, Dec 10 - Wed, Dec 11
10:32 am - 6:02 pmDSM-SAN
9h 30m1 stop
10:15 pm - 9:52 amSAN-DSM
9h 37m1 stop
$335Delta
Find Deal
Tue, Jan 14 - Mon, Jan 20
5:45 am - 12:39 pmDSM-SAN
8h 54m2 stops
7:00 am - 4:11 pmSAN-DSM
7h 11m1 stop
$339United Airlines
Find Deal
Wed, Jan 15 - Sun, Jan 19
2:15 pm - 8:50 pmDSM-SAN
8h 35m2 stops
1:55 pm - 10:00 pmSAN-DSM
6h 05m1 stop
$345Southwest
Find Deal
Tue, Feb 4 - Fri, Feb 7
5:45 am - 9:30 amDSM-SAN
5h 45m1 stop
7:00 am - 4:11 pmSAN-DSM
7h 11m1 stop
$349United Airlines
Find Deal
Mon, Jan 20 - Thu, Jan 23
4:00 pm - 9:55 pmDSM-SAN
7h 55m2 stops
12:15 pm - 10:00 pmSAN-DSM
7h 45m2 stops
$350Southwest
Find Deal
Tue, Feb 4 - Fri, Feb 7
5:39 pm - 11:59 pmDSM-SAN
8h 20m1 stop
6:40 am - 4:34 pmSAN-DSM
7h 54m1 stop
$371American Airlines
Find Deal
Sat, Jan 4 - Sat, Jan 11
5:39 pm - 9:59 pmDSM-SAN
6h 20m1 stop
8:30 am - 5:49 pmSAN-DSM
7h 19m1 stop
$372American Airlines
Find Deal
Sat, Jan 4 - Sat, Jan 11
7:00 am - 1:00 pmDSM-SAN
8h 00m1 stop
$167Delta
Find Deal
Tue, Dec 10
6:00 am - 12:27 pmDSM-SAN
8h 27m2 stops
$172United Airlines
Find Deal
Sun, Dec 15
5:07 pm - 11:49 pmDSM-SAN
8h 42m1 stop
$189Frontier
Find Deal
Mon, Dec 9
5:39 pm - 9:59 pmDSM-SAN
6h 20m1 stop
$204American Airlines
Find Deal
Sat, Jan 4
7:15 am - 1:00 pmDSM-SAN
7h 45m2 stops
$212Southwest
Find Deal
Sun, Feb 23
8:00 am - 6:40 amDSM-SAN
24h 40m2 stops
Mon, Dec 2
2:05 pm - 8:00 pmDSM-SAN
7h 55m2 stops
$258Southwest
Find Deal
Sat, Dec 7
8:00 am - 10:30 amDSM-SAN
28h 30m3 stops
Mon, Dec 2
2:29 pm - 6:24 pmDSM-SAN
5h 55m1 stop
$369American Airlines
Find Deal
Thu, Dec 5
7:06 pm - 11:56 pmDSM-SAN
6h 50m1 stop
$384Frontier
Find Deal
Mon, Dec 2
7:06 pm - 11:56 pmDSM-SAN
6h 50m1 stop
6:25 am - 6:30 pmSAN-DSM
10h 05m1 stop
$543Frontier
Find Deal
Mon, Nov 25 - Sat, Nov 30
5:50 am - 12:00 pmDSM-SAN
8h 10m1 stop
6:45 am - 4:55 pmSAN-DSM
8h 10m1 stop
$701Southwest
Find Deal
Thu, Nov 21 - Thu, Nov 28
4:00 pm - 10:25 pmDSM-SAN
8h 25m2 stops
6:45 am - 4:55 pmSAN-DSM
8h 10m1 stop
$706Southwest
Find Deal
Thu, Nov 21 - Thu, Nov 28
4:00 pm - 10:25 pmDSM-SAN
8h 25m2 stops
6:45 am - 3:50 pmSAN-DSM
7h 05m2 stops
$711Southwest
Find Deal
Thu, Nov 21 - Thu, Nov 28
6:35 am - 2:45 pmDSM-SAN
10h 10m1 stop
11:26 am - 10:43 pmSAN-DSM
9h 17m1 stop
$976Delta
Find Deal
Thu, Nov 21 - Mon, Nov 25
11:25 am - 7:53 pmDSM-SAN
10h 28m2 stops
4:09 pm - 11:49 pmSAN-DSM
5h 40m1 stop
$981United Airlines
Find Deal
Thu, Nov 21 - Mon, Nov 25
8:00 am - 5:28 pmDSM-SAN
11h 28m2 stops
6:15 am - 4:14 pmSAN-DSM
7h 59m2 stops
$986United Airlines
Find Deal
Thu, Nov 21 - Mon, Nov 25
8:00 am - 5:28 pmDSM-SAN
11h 28m2 stops
10:45 am - 9:34 pmSAN-DSM
8h 49m2 stops
$1,207United Airlines
Find Deal
Mon, Nov 25 - Sat, Nov 30
6:00 am - 9:33 amDSM-SAN
5h 33m1 stop
10:57 am - 9:46 pmSAN-DSM
8h 49m1 stop
$1,336United Airlines
Find Deal
Fri, Nov 22 - Sun, Nov 24
3:20 pm - 11:58 pmDSM-SAN
10h 38m2 stops
7:05 am - 4:14 pmSAN-DSM
7h 09m1 stop
$1,341United Airlines
Find Deal
Fri, Nov 22 - Sun, Nov 24

Flights from Des Moines to San Diego - Travel Insights & Trends

Get data-powered insights and trends into flights from Des Moines to San Diego to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Des Moines to San Diego?

The average price of all flights from Des Moines to San Diego clicked on KAYAK for each day over the last 12 months.
For Des Moines to San Diego, Monday is the cheapest day to fly on average and Sunday is the most expensive. Flying from San Diego back to Des Moines, the best deals are generally found on Monday, with Sunday being the most expensive.

What is the cheapest month to fly from Des Moines to San Diego?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for flights from Des Moines to San Diego, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.
The cheapest month for flights from Des Moines to San Diego is June, where tickets cost $267 on average. On the other hand, the most expensive months are March and February, where the average cost of tickets is $467 and $458 respectively.

How far in advance should I book a flight from Des Moines to San Diego?

To calculate daily average prices, KAYAK takes all prices for each day before departure over the last year for flights from Des Moines to San Diego, removes the top 0.1% to account for outliers, and then takes the average of all the values for each month.
To get a below average price on the flight from Des Moines to San Diego, you should book around 3 days before departure. For the absolute cheapest price, our data suggests you should book 22 days before departure.

Good to know

Low season

February

High season

July

Cheapest flight

$158
Best time to beat the crowds but there is an average 19% increase in price.
Most popular time to fly and prices are also 28% lower on average.
Flight from Des Moines to San Diego

When to book flights from Des Moines to San Diego

Are your dates flexible? Find out the best times to travel from Des Moines to San Diego based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Des Moines to San Diego

  • Where can I park at DSM before my flight to San Diego?

    The Long-Term Premium and Long-Term Parking Lots are close enough that you can walk to the terminal. However, the more affordable options, the Blue Lot Economy 2, the Green Lot Economy 3, and the Gray Lot Economy 4, are not within walking distance. But you can take a free shuttle from the Economy Lots to the terminals. At DSM, you cannot reserve parking in advance, but the homepage on the DSM website keeps track of how much space is available in each lot and the Live Shuttle Tracker tells you when the next shuttle is coming.

  • Does DSM provide facilities for nursing moms?

    Yes. There is a Mamava lactation suite located just after the TSA checkpoint near the DSM police desk. Regardless of which concourse you're going to, everyone passes through the same security checkpoint in the main terminal. Each freestanding Mamava unit contains a fold-down table, bench seating on either side, a USB port, an electrical outlet, a coat hook, and a mirror.

  • Does SAN have a military lounge?

    Yes. The USO at SAN is in Terminal 2, landslide. If you are traveling soldier or a member of a military family who wants to relax, regroup, or refresh after your flight from Des Moines, you can visit the USO and enjoy its benefits and facilities free of charge. Amenities include showers, comfortable seating, refreshments, TV, unlimited domestic calls, and much more.

  • Where can I pick up my rental car at SAN?

    All car rental companies are located in a separate building outside the SAN airport. At the Arrivals curb, you can catch a free shuttle to whichever car rental agency you need to go to. Some car rental agencies at San Diego Airport include Avis, Enterprise, Budget, Alamo, Hertz, Firefly, National, and more.

  • What is the cheapest flight from Des Moines to San Diego?

    In the last 3 days, the lowest price for a flight from Des Moines to San Diego was $167 for a one-way ticket and $158 for a round-trip.

  • Do I need a passport to fly between Des Moines and San Diego?

    A passport is not required to fly from Des Moines to San Diego.

  • Which airports will I be using when flying from Des Moines to San Diego?

    When flying out of Des Moines you will be using Des Moines. You will be landing at San Diego, also known as San Diego.

  • Which aircraft models fly most regularly from Des Moines to San Diego?

    The Airbus A320-100/200 is the aircraft model that flies most regularly on the Des Moines to San Diego flight route.

  • Which airline alliances offer flights from Des Moines to San Diego?

    SkyTeam, Star Alliance, and oneworld are the airline alliances operating flights between Des Moines and San Diego, with SkyTeam being the most commonly used for this route.

  • What is the most popular layover when flying to San Diego from Des Moines?

    Denver is the most popular layover city among KAYAK users traveling from Des Moines to San Diego.

  • Which is the best airline for flights from Des Moines to San Diego, Southwest or Delta?

    The two airlines most popular with KAYAK users for flights from Des Moines to San Diego are Southwest and Delta. With an average price for the route of $426 and an overall rating of 8.1, Southwest is the most popular choice. Delta is also a great choice for the route, with an average price of $426 and an overall rating of 8.0.

  • How does KAYAK find such low prices on flights from Des Moines to San Diego?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to San Diego.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to San Diego?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Diego from Des Moines is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to San Diego?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Diego with an airline and back to Des Moines with another airline. Booking your flights between Des Moines and SAN can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to San Diego?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Diego from Des Moines up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

KAYAK’s top tips for finding a cheap flight from Des Moines to San Diego

  • Looking for a cheap flight? 25% of our users found flights on this route for $272 or less round-trip.
  • Located virtually in the center of the state of Iowa, the Des Moines International Airport (DSM) serves as a focus city for Allegiant Air. The San Diego International Airport (SAN), located on the Pacific coast in California just north of the Mexican border, is a hub for Southwest, Alaska Airlines, and other smaller airlines.
  • Though is unlikely you will find a direct flight from Des Moines to San Diego, you can find one-stop flights on several airlines, such as United, often with a stop in Denver. Southwest, American, and Delta also have one-stop flights with layovers in cities such as Dallas, Phoenix, Minneapolis, in Atlanta. United, American, and Delta are among the airlines offering two-stop flights as well.
  • There is one animal relief area at DSM located outside the terminal. So, remember to make sure that your service animal or your pet goes to the bathroom before you enter the airport and go through security. This animal relief area is north of the Skywalk next to the parking garage.
  • A baggage claim at SAN, you can find the service Traveler’s Aid. Open every day from 8 am to 11 pm, Travelers Aid helps passengers who are stranded or distressed. For example, if your accommodation plans have fallen through, if your money has been lost or stolen, or if you need transportation assistance, Travelers Aid is there to help.
  • If you feel stiff and sore after your flight from Des Moines, consider getting a massage at one of the two Be Relax Spa locations at the San Diego Airport. There is one spa location at Gate 26 in Terminal 2 and another location atG ate 36 in Terminal 2. These spas are open daily from 7 am to 8 pm.
See more tips

Top 5 airlines serving from Des Moines to San Diego

 
See real verified KAYAK customer reviews for airlines flying from Des Moines to San Diego. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Des Moines to San Diego? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.1
SouthwestOverall score based on 5015 reviews
7.2Food
8.1Comfort
8.2Boarding
7.7Entertainment
8.7Crew
Airline reviews

Was as expected. Crowed planes. Too many carryons delaying takeoff. But the ride only took an hour and saved me a lot of time SFO is a not a great airport.

8.0 ExcellentMark, Oct 2024LAX - SFO
Read more Southwest reviews

Was as expected. Crowed planes. Too many carryons delaying takeoff. But the ride only took an hour and saved me a lot of time SFO is a not a great airport.

Was as expected. Crowed planes. Too many carryons delaying takeoff. But the ride only took an hour and saved me a lot of time SFO is a hell hole of an airport. It is the new LaGuardia. Everything Cobbled together. Security gates closed. Terri directional signage

I will be flying again Southwest Airlines. Friendly crew, comfortable and affordable.

The plane arrived 25 minutes late, and the Wi-Fi was slower than it usually is.

Forget beverage, they didn't even have water for half the passangers?

Can not wait for seating change to reduce the amount of pre boards - it’s disheartening the abuse. And then then deplaning

The crew was nice. Boarding sucked. Instead of loading from the back to the front people just sat wherever and you had to wait for them to move to get to a seat. And the flight was 25 minutes delayed.

I boarded last because of my boarding assignment and was given a middle seat at the back of the plane. I’m 6”1” so it was really tight. I wish I just had a seat assignment instead of a general boarding group. My bag was way at the front and my seat at the back. Was never offered a beverage and had no room to move.

The open seating makes passengers boarding ahead of you think they also have the right to the empty middle seat. Trumper next to me refused to move her laptop bag from my leg area. I did not make a fuss since it was a short flight.

Flight was delayed more than 2 hour do the scheduling issues and then some confusing weight and balance matters, followed by a miscommunication with the tower on which runway was going to be used based on the airplane weight. All these things should have been figured out in advance. Instead of arriving at 12:30 a.m. we arrived at 2:30 a.m. very difficult to find a taxi or other transport at SFO. Luggage was delayed. An extension of an unpleasant flight day

Cabin was pitch black, even during meal service. The reading lights for seat 2E/F did not work, and seat 2E did not recline.

This was a 5 hour flight with no entertainment and with a snack being provided (pretzels and fruit bar), which are both high in carbs and sugar. Nuts would have been a better choice.

Liked that we left on time for each flight. Snacks not the best, but we're okay.

Was realllly smooth. It was delayed but we were well informed.

Good plane, crew, and flight. Boarding was a bit chaotic. Bathrooms were unacceptable. United DESPERATELY needs a new terminal at IAD.

Haven’t used United in a while. Was surprised with the free blanket and earphones. Service was great. Huge plane. 9/.row.

Delayed by 2.5hrs any longer and they would’ve had to honour their own policy for breaking their own rules and regs. Not cool, especially when I have an infant child that needs to stay on a routine and they get schedules.

To san Francisco it was ok. From sf to Manila it was horrible

Awful, rude staff. Their abrasive comments are unnecessary. Most seek a frictionless experience and will cooperate if you ask. Additional childish bullying of customers is not acceptable or tolerated. We had the same problem with our departure flight. We will never fly United again.

Very poor the plane itself was really old, slight smell that couldn’t be named. I didn’t even get a boarding pass UNTIL AFTER clearing security! Even then, they said when I get to my connected flight I’ll get my 2nd boarding pass there! A bit ridiculous!

Terrible. Still have not received the refund from them. They sent it to some account that I don't even know. Spoke with costumer service and they are unable to help.

I didn’t like it at all. I miss my second flight because of the delay on Allegiant Air now I m stuck in MCO.

Good, but a bit late on take off after loading. Don't like charging for carry ons!

First time flying with them and will definitely fly again in the future. Crew was so nice and friendly, fought was seamless. They are simple planes, no entertainment, but it’s fine for a short flight or if you have personal devices Rates are competitive, and they did so well with keeping the flight on time after a tropical storm, where other airlines had delays and cancellations.

They boarded passengers that sat in the back of the plane first, making boarding very efficient.

I didn't even take this flight. My plans changed and I couldn't get ahold of customer service and the website kept breaking down during the attempt to change the flight. I wound up taking another airline entirely and eating the cost.

The worst flying experience ever 3 delays. No accommodations. Had to deboard the plane after being delayed.

Posted a 20minute delay but didn’t delay at all. Caused boarding issues and confusion. Also, didn’t release baggage. Took over an hour and 20 minutes to get luggage.

Flight was good, boarding was a breeze, flight attendants were friendly and professional. There was a medical issue with another passenger and the crew handled it in a calm and professional way.

The net issue I had was with the gate agent. We had added a carryon to our boarding pass when we checked bags. When I got to the boarding gate the agent was rude asking why I had a backpack - I said I added it - even had an orange tag on it. She ripped my tag off and swung her monitor around to show me how she was right- saying it isn’t wasn’t listed - only a checked bag. I explained again that I wasn’t sure what the issue was but I wouldn’t have an orange tag if I hadn’t added it. Then she finally checked my husband’s boarding pass and found that the agent at checkin had added my carryon to his boarding pass instead of mine. She sent me on my way without my orange tag. Was a bit embarrassing for me the tone she used with me assuming I was trying to get away with something.

My boarding pass wouldn't pull up in the app very easily and had to really dig through my email. That caused a delay in TSA..

It was exactly what I expected, actually arriving sooner than scheduled.

RE Food: Wish there was a choice for No Rating. Flew from Honolulu to Los Angeles on a Red-Eye flight (11:00 pm to 7:30 am). Other than a package of cookies with a beverage choice offered soon after take-off, and a beverage choice shortly before landing, no other food choices were offered. Everyone slept or rested for most of the trip. Nothing to rate. RE Entertainment: Everyone was sleeping most of the flight. Only saw one passenger watch about 30 minutes of entertainment on his iPad. I never attempted to access any entertainment options.

Baby cried a lot. Nothing anyone could do about it. Just part of flying.

For coast to coast travel the A321 and even the NEO, even in first class will never be excellent. That would take a B787 or 777 to accomplish.

The flight crew was fantastic! Which the seats had a small TV.

The foot ottoman cushion was missing on my business class seat.. the hydraulics is on its last leg & seat cushions do not have support or paddling. Heavily dented by butts

also wi-fi never worked attendant said satellite coverage is spotty over water ..... but we were over land!

I was unhappy with having the seat I chose changed at the last minute. I was moved to an aisle seat which did not recline and was next to the bathroom. The bathroom odors made the flight entirely unpleasant. Having carefully chosen my seat months before I was not pleased with my AA experience. In addition, they ran out of tea during flight service, really?

Dallas Hub. American taking ownership for their screwups instead of blaming their contractors and customers, trading their people, their call in service, reservation agents and their ticketing process. Make sure wheelchairs are available especially when the request is in their record.

My first flight was moved 6 hours causing me to miss my meeting. The second was delayed about an hour and a half. Most of the crews apparently dont like their jobs or just working for Frontier. Only one flight attendant wasn"t snappy or rude.

Booked direct in July '24. Turned into a 14 hr layover (both ways) in Denver. My 5 day vaca turned into a 1 day . Not good, BUT,... Thank you for the people @ Frontier who were professionally friendly & approachable.

Stop changing gates at sfo. When you are elderly going back for it’s not fun.

We understand and comply with Frontier’s bag sizes. We’ve had some problems in past while having to await other passengers who do not understand the baggage restrictions or have not prepaid and that is usually our biggest concern (others delaying us) with flying Frontier. Flying OUT of ONT, however, has always been a great experience. I’ve also noted even on delayed Frontier flights very knowledgeable pilots who manage expectations well.

There was no easy way to check in. I don't want to install an app to checkin. I will use alaska from now on because they have a web check in method that is easy.

The crew was ghetto lol I felt like I was on an inner city field trip

Horrible! The short distance flight ended up taking 5 hrs! There was a 3 hr delay for the flight to take off and there was a 70 min wait on the tarmac for some bogus reason that the pilot said the gate he was supposed to board was taken up. After a 30 min wait he said the plane that was supposed to push out of the gate called a medical emergency and 40 min later he ended up boarding another gate. For the initial 3 hr delay there was no information/alert about the gate or delay in the app or the boards up until the boarding time and even beyond! Had to walk all the way to the end of the terminal to find the frontier staff to ask what was going on. Avoid this airline at all costs! If you have carryon bags or checked bags , their prices come equivalent to the prices of more reliable airlines. They are the worst in timeliness at 60% (reported as delayed) this year (check the data) by a high margin even compared to the second worst airline. If you are ok with having a miserable flight experience with the odds close to flip of a coin, feel free to try them. If you value your time , money and flying experience, stay away.

There was nothing to like, flight delayed had to move to different departure areas, disorganized to say the leasr

Delayed for two hours due to trivial issues. No reimbursment. Also on arrival further delay due to terminal malfunction.

Our flight was canceled for no known reason. We weren’t told until we were checking in at 5:00 am. This was after our last flight with Frontier where we sat on the plane for three hours (not an exaggeration) before we took off because of a mechanical issue. We won’t be flying Frontier again.

Book cheap flights from Des Moines to San Diego

Recent one-way flight deals

 
Only flying one-way? Below are some of the best one-way flight deals from Des Moines to San Diego found on KAYAK in the last 72 hours.
12/10Tue
1 stopDelta
8h 00mDSM-SAN
$167
12/15Sun
2 stopsUnited Airlines
8h 27mDSM-SAN
$172
12/9Mon
1 stopFrontier
8h 42mDSM-SAN
$189
1/4Sat
1 stopAmerican Airlines
6h 20mDSM-SAN
$204
2/23Sun
2 stopsSouthwest
7h 45mDSM-SAN
$212
12/2Mon
2 stops
24h 40mDSM-SAN
$231
12/7Sat
2 stopsSouthwest
7h 55mDSM-SAN
$258
12/2Mon
3 stops
28h 30mDSM-SAN
$307
12/5Thu
1 stopAmerican Airlines
5h 55mDSM-SAN
$369
12/2Mon
1 stopFrontier
6h 50mDSM-SAN
$384

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Last minute flights from Des Moines to San Diego

Last minute flight, train and bus deals

 
These last-minute flight deals are the cheapest flights found on KAYAK in the last 72 hours for flights from Des Moines to San Diego that are departing in the next 10 days.
11/25Mon
multi-stopFrontier
6h 50mDSM-SAN
11/30Sat
multi-stopFrontier
10h 05mSAN-DSM
$543
11/21Thu
multi-stopSouthwest
8h 10mDSM-SAN
11/28Thu
multi-stopSouthwest
8h 10mSAN-DSM
$701
11/21Thu
multi-stopSouthwest
8h 25mDSM-SAN
11/28Thu
multi-stopSouthwest
8h 10mSAN-DSM
$706
11/21Thu
multi-stopSouthwest
8h 25mDSM-SAN
11/28Thu
multi-stopSouthwest
7h 05mSAN-DSM
$711
11/21Thu
multi-stopDelta
10h 10mDSM-SAN
11/25Mon
multi-stopDelta
9h 17mSAN-DSM
$976
11/21Thu
multi-stopUnited Airlines
10h 28mDSM-SAN
11/25Mon
multi-stopUnited Airlines
5h 40mSAN-DSM
$981
11/21Thu
multi-stopUnited Airlines
11h 28mDSM-SAN
11/25Mon
multi-stopUnited Airlines
7h 59mSAN-DSM
$986
11/25Mon
multi-stopUnited Airlines
11h 28mDSM-SAN
11/30Sat
multi-stopUnited Airlines
8h 49mSAN-DSM
$1,207
11/22Fri
multi-stopUnited Airlines
5h 33mDSM-SAN
11/24Sun
multi-stopUnited Airlines
8h 49mSAN-DSM
$1,336
11/22Fri
multi-stopUnited Airlines
10h 38mDSM-SAN
11/24Sun
multi-stopUnited Airlines
7h 09mSAN-DSM
$1,341

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