DSM - SAT

$149 Find Cheap Flights from Des Moines to San Antonio

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to San Antonio departing on 5/31. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult

KAYAK searches hundreds of travel sites at once for deals on flights to San Antonio

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to San Antonio, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to San Antonio, as well as popular online travel agencies
Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 22% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Cheap Flights from Des Moines to San Antonio

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to San Antonio that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.

Recent round-trip flight deals from Des Moines to San Antonio

KAYAK's recommended round-trip deals from the most popular airlines that fly from Des Moines to San Antonio.
Discover the best prices for you by selecting your travel dates on KAYAK.
Choose your dates
Frontier Logo
8:20 pm - 6:51 pmDSM-SAT
22h 31m1 stop
Frontier Logo
7:50 pm - 7:53 pmSAT-DSM
24h 03m1 stop
$241Frontier
Find Deal
vie., may. 30 - dom., jun. 1
Frontier Logo
8:20 pm - 6:51 pmDSM-SAT
22h 31m1 stop
Frontier Logo
7:50 pm - 7:53 pmSAT-DSM
24h 03m1 stop
$261Frontier
Find Deal
vie., may. 30 - dom., jun. 1
Delta Logo
6:30 am - 12:36 pmDSM-SAT
6h 06m1 stop
Delta Logo
2:38 pm - 9:06 pmSAT-DSM
6h 28m1 stop
$297Delta
Find Deal
sáb., may. 31 - sáb., jun. 7
Delta Logo
5:30 pm - 11:09 pmDSM-SAT
5h 39m1 stop
Delta Logo
6:25 am - 12:27 pmSAT-DSM
6h 02m1 stop
$300Delta
Find Deal
jue., may. 29 - lun., jun. 2
American Airlines Logo
7:43 pm - 11:37 pmDSM-SAT
3h 54m1 stop
American Airlines Logo
5:04 am - 9:02 amSAT-DSM
3h 58m1 stop
$303American Airlines
Find Deal
vie., sep. 5 - dom., sep. 7
American Airlines Logo
4:22 pm - 10:05 pmDSM-SAT
5h 43m1 stop
American Airlines Logo
6:45 pm - 10:41 pmSAT-DSM
3h 56m1 stop
$335American Airlines
Find Deal
vie., ago. 29 - lun., sep. 1
United Airlines Logo
1:10 pm - 10:58 pmDSM-SAT
9h 48m2 stops
United Airlines Logo
5:58 pm - 10:30 pmSAT-DSM
4h 32m1 stop
$388United Airlines
Find Deal
vie., sep. 5 - dom., sep. 7
United Airlines Logo
11:30 am - 10:58 pmDSM-SAT
11h 28m2 stops
United Airlines Logo
5:30 am - 1:56 pmSAT-DSM
8h 26m2 stops
$393United Airlines
Find Deal
vie., sep. 5 - dom., sep. 7
Southwest Logo
6:00 am - 3:30 pmDSM-SAT
9h 30m2 stops
Southwest Logo
1:00 pm - 11:00 pmSAT-DSM
10h 00m1 stop
$458Southwest
Find Deal
jue., may. 1 - dom., may. 4
Southwest Logo
6:00 am - 3:30 pmDSM-SAT
9h 30m2 stops
Southwest Logo
5:45 pm - 11:55 pmSAT-DSM
6h 10m2 stops
$468Southwest
Find Deal
jue., may. 1 - dom., may. 4

KAYAK's insights & trends for Des Moines to San Antonio flights

Get data-powered insights and trends into flights from Des Moines to San Antonio to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Des Moines to San Antonio?

The average price of all round-trip flights from Des Moines to San Antonio clicked on KAYAK for each day over the last 12 months.
For Des Moines to San Antonio, Wednesday is the cheapest day to fly on average and Monday is the most expensive. Flying from San Antonio back to Des Moines, the best deals are generally found on Tuesday, with Sunday being the most expensive.

What is the cheapest month to fly from Des Moines to San Antonio?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Des Moines to San Antonio, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.
The cheapest month for flights from Des Moines to San Antonio is July, where tickets cost $316 (return) on average. On the other hand, the most expensive months are March and February, where the average cost of round-trip tickets is $476 and $436 respectively.

How far in advance should I book a flight from Des Moines to San Antonio?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Des Moines to San Antonio, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.
To get a below average price on the flight from Des Moines to San Antonio, you should book around 3 weeks before departure. For the absolute cheapest price, our data suggests you should book 26 weeks before departure.

Good to know

Low season

June

High season

March

Cheapest flight

$149
Best time to beat the crowds with an average 4% drop in price.
Most popular time to fly with an average 24% increase in price.
Flight from Des Moines to San Antonio

When to book flights from Des Moines to San Antonio

Are your dates flexible? Find out the best times to travel from Des Moines to San Antonio based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Des Moines to San Antonio

  • What is the cheapest flight from Des Moines to San Antonio?

    In the last 3 days, the lowest price for a flight from Des Moines to San Antonio was $149 for a one-way ticket and $241 for a round-trip.

  • Do I need a passport to fly between Des Moines and San Antonio?

    A passport is not required to fly from Des Moines to San Antonio.

  • Which airports will I be using when flying from Des Moines to San Antonio?

    When flying out of Des Moines you will be using Des Moines. You will be landing at San Antonio, also known as San Antonio.

  • Which aircraft models fly most regularly from Des Moines to San Antonio?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Des Moines to San Antonio?

    oneworld, SkyTeam, and Star Alliance are the airline alliances operating flights between Des Moines and San Antonio, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from Des Moines to San Antonio, Delta or Southwest?

    The two airlines most popular with KAYAK users for flights from Des Moines to San Antonio are Delta and Southwest. With an average price for the route of $365 and an overall rating of 8.0, Delta is the most popular choice. Southwest is also a great choice for the route, with an average price of $396 and an overall rating of 8.0.

  • How does KAYAK find such low prices on flights from Des Moines to San Antonio?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to San Antonio.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to San Antonio?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Antonio from Des Moines is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to San Antonio?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Antonio with an airline and back to Des Moines with another airline. Booking your flights between Des Moines and SAT can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to San Antonio?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Antonio from Des Moines up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Top 5 airlines serving from Des Moines to San Antonio

 
See real verified KAYAK customer reviews for airlines flying from Des Moines to San Antonio. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Des Moines to San Antonio? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4280 reviews
8.0Comfort
7.1Food
8.6Crew
8.2Boarding
7.6Entertainment
Airline reviews

Plz don't take away free bags and free seating

10.0 ExcellentAnonymous, Apr 2025DAL - FLL
Read more Southwest reviews

Plz don't take away free bags and free seating

The seats were a bit cramped and worn, but otherwise okay.

I would have liked to arrive on time - not 5 hours late!

After a 3 hour layover in Denver my flight was delayed over 5 hours! No explanation; no assistance; no offer to provide compensation; no one at Southwest was willing to offer any assistance. 8 hours in the Denver airport - ridiculous!

It was a perfect flight in all aspects! Both legs!

Only one drink pass through the cabin for a 4 hour flight. Quite rough and bumpy landing.

Multiple delays and gate changes. Arrived at final destination 6 hours late. All rental cars had been taken.

The movies using Southwest WiFi kept pausing and I had to restart multiple times.

First, my flight was a usual flight nothing exceptional or unexpected. Over all it was a normal, good flight! Second, your questionaire is wholly lacking in the proper options to which one can answer a question. Often on short flights, there is no food let alone entertainment so why isn't that reflected in your questionaire? A simple "not applicable" would cover that issue appropriately but no, your form arbitrarily enters an answer based on the initial assessment which normally isn't factual. Until you provide an accurate means of assessing flights, I'll no longer be completing of these unimpressive and misleading assessements. Thank you!

Easy to book and to get check in and get on and off.

This had nothing to do with Delta… The flights were on time and flawless. The service was excellent. We purchased seats in (aisle/middle) comfort plus since this was a cross country flight. Unfortunately, the woman seated at the window was 300+ pounds and, as might be expected, covered up about a third of the middle seat also. there was absolutely nothing that Delta could have done about that… I just don’t know what the answer should be. If you purchase a seat, you should should be able to use the entire seat and not just the portion that someone else is not sitting/oozing in. Disappointing…there should be something that could be done….I'm just not sure what solution could be.

Delayed take-off. Very small plane so very scary with lots of bumps during the flight. Would never fly Delta on short flights in small 80 seaters plane again! Felt relieved when landed.

The worst part was I was NOT allowed in the lounge even though I was holding a first class ticket and have a premium American Express card. I have flown Business or First Class with many airlines. Delta is the ONLY one who does not extend this courtesy to anyone except people who hold the very expensive American Express card. As a result, I won’t fly Delta if I have any other choice.

A little bumpy ride . No food was being provided due the the turbulence. That was ok it was a short flight to my standards.

Simply outstanding. Their new lounge for Delta One customers is a cut above the rest.

The Dekta Rep that checked us in was great. She's very personable, pleasant, and can tell she enjoys her job.

The plane was old with small storage areas that had problems closing/latching and not enough storage for everyone, and worn, damaged seats. Service was great but feel a little unsafe on such well used planes.

Terrible and im avoiding them in the future. My initial flight was delayed causing me to rebook my flight and when speaking with the representative to rebook I explained this is the second time my flights were delayed and they did nothing to help me. I wasn't booked to comfort plus or given a voucher or anything. I was almost late for my meeting that I needed to attend on Monday because of the games delta played delaying my flights even more and putting me in the very back of the plane next to an extremely intoxicated passenger

Flights on time. .Ride was as comfortable as can be expected in steerage. Luggage arrived at destination. Attendants were fairly friendly.

Great staff. Wifi is terrible. Signing up for skylines is a painstaking process. Had to call customer service just to get my flight itinerary and confirmation sent to me. Consistent delays. A well staffed company that is run so poorly. Upper management needs to be renewed.

The plane pushed back from the gate on time. However, it stopped on the ramp, and we waited for over 20 minutes before the aircraft pulled back to the gate. Apparently, something of importance had to be removed from the aircraft by the gate agent. I found this to be odd. The delay was not significant, but I felt that whatever was on the aircraft that had to be taken off, should’ve been done before we pushed back from the gate.

Smooth boarding process. Early departure, smooth flight, early arrival. The entertainment package has very good recent movie options. The flight crew were friendly and professional.

I don’t understand the purpose of the orange “priority” tag on my bag. This tagged, my bag is last or near to the last bag to come down the carousel at IAH.

Oh my gosh, I loved my experience with United! they made me want to travel more often.

The planes are so dirty! Food crumbs and finger print smudges, Dust over the vents and carpet stains. It’s disgusting.

The bag drop personal were not helpful. There was no food on the flight. Boeing aircraft, lousy as always. Everything else was fine.

Asked several times dairy free options and was ignored. Was told chips was the only thing I could have that I should have put it on my profile “which it is”. Very unprofessional. WiFi didn’t work have the flight. Overall a very bad experience.

Plane still had screens for watching movies. Good selection too.

Flight crew was amazing! I don't like that the Polaris seats are side-by-side.

Everything was awful Flight attendant was condescending, rude and not helpful at all. Small outdated plane. No service, uncomfortable seats. Flight attendant was really the worst. He used hand gestures to communicate instead of words and whenever he used words he was condescending.

The flight to Tokyo AA61 took off about two hours late, but then had to turn back. By that time the crew had to be replaced. Then they kept promising to take off in an hour, then in 3, then switch to the next day.

Any sort of gluten free snack option would be nice

I had a carry on and a personal bag. I put my personal item under my seat and on way to the seat I put my bag up. I usually close my eyes and rest as I was on call for last 36 hours. I heard very loud announcements that someone needs to identify their bag. Pretty sure it was not mine until the hostess pointed out my jacket details attached to the bag. I asked why she got my bag out. I got berated and did not want to create a scene. But this person needs to be talked to.

Between Las Vegas and Dallas was okay But, once in the Dallas airport, notice, I have disability and ask for a wheelchair, they leave in a middle of nowhere, the personal in charge try to push me on a cart where I couldn't sit because was to high. Then they don't care about me, they bulling, till I start to yelling and crying, ask to everyone around, who can help me. The man in charge make a despective movements and said you are to loosing the fly. The last name in his batch started with an H, I did not have the full name. A nightmare. After all, a woman in charge was walking very slowly and asking me for a tip cause she was helping me to reach the fly. For years, AA has been the preferred airline. The personal in charge of the disabled people are discriminate me. Thank you Kayak.

Flight was late and missed connecting flight. They could have better accommodated, but instead did an overnight and had to arrive the next afternoon.

Awkward carry on process. Forced to check all carry on. No overhead space of worthiness. Left delayed, but made up the time. Crew was amicable.

April was the flight attendant in first class and was the most pleasant, cordial and efficient person I have seen on a flight in years. Good example of the type of people AA should hire to increase customer satisfacdtion.

Two flight changes before the scheduled flight. On the day of the flight, the flight was delayed, which caused the connecting flight to be missed. Then, I was directed to another airport (CUN) and traveled to Tulum. American gave a $12 voucher for lunch. The least expensive item on the menu at a Mexican restaurant was $9.99. Driving to Tulum was a bad auto crash, and traffic was delayed two-plus hours. The bottom line is that we should have been at the hotel at noon, but it ended up at 11:30 PM.

The boarding experience was good; $20 for wifi per flight is uncompetitive compared to Delta, Southwest, and others, and puts American lower on my list given similar pricing.

Flight didn’t get dinner on business. I was starving!

It was a short flight so no food or entertainment….

Seats are uncomfortable but price is good. Guess I can put up with misery for four hours.

I’ve never traveled on Frontier before. If you want basic, no frills, friendly service at great prices then give them a fly!

Cancelled and declined to find alternatives Earlier flight is 2 days later Sent the cancellation notification very late, wish I knew earlier would have stayed to watch the Miami open final game Very disappointing service

The worst flight of my life. Never will I fly frontier again

Landing in terminal 2, but my luggage is terminal 3. We (and others) were looking for it in terminal 1. We probably missed the crew broadcast, but the communication could have been clearer for non native (or elderly) passengers.

I chose the seats when booked the flight and paid for them. However after checking in I found we were assigned different seats!

Bag should not be so much money. This is how Frontier takes advantage of customers

The plane was comfortable. The time to board was way too slow and very unorganized! The crew was not as friendly as normally. The was not a single time that they offered water nor anything!!!

They switched my flight to Spirit, Never using Kayak again,

Everything you need to know for your flight from Des Moines to San Antonio

Information on your arrival and departure airports

Not what you’re looking for? Find thousands of other hotels, flights, car rentals and package deals with KAYAK.