$99 Find Cheap Flights from Charlotte to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Charlotte to South America departing on 2/23. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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1 adult, Economy, 0 bags

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Cheap Flights from Charlotte to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima1 stop$302
Bogotá
Bogotá2 stops$246
Buenos Aires
Buenos Aires3 stops$817
Sao Paulo
Sao Paulo1 stop$596
Rio de Janeiro
Rio de Janeiro2 stops$637
Santiago
Santiago2 stops$647
Cartagena
Cartagena1 stop$253
Quito
Quito3 stops$408
Guayaquil
Guayaquil1 stop$264
Cali
Cali1 stop$293
Cusco
Cusco2 stops$534
Pereira
Pereira3 stops$398
Montevideo
Montevideo2 stops$870
Barranquilla
Barranquilla1 stop$353
Santa Marta
Santa Marta2 stops$889
Lima
Lima1 stop$302
Bogotá
Bogotá2 stops$246
Buenos Aires
Buenos Aires3 stops$817
Sao Paulo
Sao Paulo1 stop$596
Rio de Janeiro
Rio de Janeiro2 stops$637
Santiago
Santiago2 stops$647
Cartagena
Cartagena1 stop$253
Quito
Quito3 stops$408
Guayaquil
Guayaquil1 stop$264
Cali
Cali1 stop$293
Cusco
Cusco2 stops$534
Pereira
Pereira3 stops$398
Montevideo
Montevideo2 stops$870
Barranquilla
Barranquilla1 stop$353
Santa Marta
Santa Marta2 stops$889

Book Cheap Charlotte to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Charlotte to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Charlotte to South America

Wed, Feb 11 - Sat, Feb 21
Spirit Airlines Logo
6:00 am - 2:15 pm
CLT
-
MDE
8h 15m1 stop
Spirit Airlines Logo
3:10 pm - 12:40 am
MDE
-
CLT
9h 30m1 stop
$224Spirit Airlines
Wed, Feb 11 - Sat, Feb 21
Spirit Airlines Logo
6:00 am - 2:15 pm
CLT
-
MDE
8h 15m1 stop
Spirit Airlines Logo
3:10 pm - 12:40 am
MDE
-
CLT
9h 30m1 stop
$225Spirit Airlines
Tue, Jan 27 - Tue, Feb 3
Spirit Airlines Logo
6:00 am - 2:15 pm
CLT
-
MDE
8h 15m1 stop
Spirit Airlines Logo
3:15 pm - 12:40 am
MDE
-
CLT
9h 25m1 stop
$235Spirit Airlines
Wed, Feb 11 - Fri, Feb 20
Spirit Airlines Logo
6:00 am - 2:15 pm
CLT
-
MDE
8h 15m1 stop
Spirit Airlines Logo
3:10 pm - 12:40 am
MDE
-
CLT
9h 30m1 stop
$242Spirit Airlines
Tue, Jan 20 - Tue, Jan 27
Spirit Airlines Logo
7:43 pm - 12:50 pm
CLT
-
BOG
17h 07m2 stops
Spirit Airlines Logo
3:06 pm - 4:54 pm
BOG
-
CLT
25h 48m2 stops
$246Spirit Airlines
Mon, Feb 9 - Thu, Feb 19
Spirit Airlines Logo
6:00 am - 2:15 pm
CLT
-
MDE
8h 15m1 stop
Spirit Airlines Logo
3:10 pm - 12:40 am
MDE
-
CLT
9h 30m1 stop
$247Spirit Airlines
Thu, Jan 22 - Wed, Jan 28
Multiple Airlines Logo
6:02 pm - 12:21 am
CLT
-
GYE
30h 19m1 stop
Multiple Airlines Logo
1:26 am - 8:55 pm
GYE
-
CLT
19h 29m1 stop
$270Multiple Airlines
Mon, Mar 2 - Fri, Mar 6
GOL Logo
2:42 pm - 10:45 am
CLT
-
VCP
18h 03m2 stops
GOL Logo
5:55 pm - 9:19 pm
VCP
-
CLT
29h 24m2 stops
$602GOL
Tue, Mar 3 - Tue, Mar 10
GOL Logo
4:13 pm - 10:45 am
CLT
-
VCP
16h 32m2 stops
GOL Logo
5:55 pm - 9:51 pm
VCP
-
CLT
28h 56m2 stops
$627GOL
Tue, Mar 3 - Tue, Mar 10
GOL Logo
2:15 pm - 1:25 pm
CLT
-
GRU
21h 10m2 stops
GOL Logo
9:00 am - 9:51 pm
GRU
-
CLT
37h 51m2 stops
$628GOL
Booking Insights

KAYAK's insights & trends for Charlotte to South America flights

Get data-powered insights and trends into flights from Charlotte to South America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Charlotte to South America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Charlotte to South America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Charlotte to South America is November, when tickets cost $693 (return) on average. On the other hand, the most expensive months are December and August, when the average cost of round-trip tickets is $865 and $848 respectively.

What’s the cheapest day of the week to fly from Charlotte to South America?

The average price of all round-trip flights from Charlotte to South America clicked on KAYAK for each day over the last 12 months.

For Charlotte to South America, Tuesday is the cheapest day to fly on average and Friday is the most expensive. Flying from South America back to Charlotte, the best deals are generally found on Tuesday, with Sunday being the most expensive.

How far in advance should I book a flight from Charlotte to South America?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Charlotte to South America, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Charlotte to South America, you should book around 4 weeks before departure, which saves you about 21% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 8 weeks before departure.

Good to know

Low seasonSeptember
Cheapest flight$99
Best time to beat the crowds with an average 20% drop in price.
Most popular time to fly with an average 25% increase in price.
Flight from Charlotte to Medellín

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Charlotte to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Charlotte to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Charlotte to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Charlotte to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Charlotte to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Charlotte to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Charlotte to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Charlotte to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to South America?

    The cheapest time of day to fly to South America is generally at night, when round-trip flights cost $685 on average. Morning departures are around 6% cheaper than evening flights, on average. The most expensive time of day to fly to South America is generally in the evening, which is peak travel time and where the average cost of a ticket is $874.

Reviews of the top 5 airlines serving from Charlotte to South America

 
Need help choosing which airline to fly with from Charlotte to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8011 reviews
7.9Entertainment
7.9Comfort
8.1Boarding
7.3Food
8.5Crew
Airline reviews

I fly Delta all the time, have Platinum Medallion status. But this route seems to have major problems with delays and seems to never leave on time! Have only taken it twice in the last two weeks, and each time it had delays of more than 1 hour... very disappointed!!!!

4.0 OkayCarl, Dec 2025
FLL - LGA
Read more Delta reviews

I fly Delta all the time, have Platinum Medallion status. But this route seems to have major problems with delays and seems to never leave on time! Have only taken it twice in the last two weeks, and each time it had delays of more than 1 hour... very disappointed!!!!

Getting to the flight was arduous and lengthy. The flight itself was good but the food option wasn’t a good selection. I need to do a Kosher option on my return. Flight crew were nice

Good seats in Main cabin, excellent service and excellent landing

My flight was cancelled with no explanation after I had already cleared security. I was given 4 options to rebook, only one being non-stop like I had paid for. I grabbed it. It was 4 plus hours later and then took off even later. Biggest complaint is that I booked early and had an aisle seat. They gave me a "window" seat in front of the exit row, so the seat did not decline. I weigh all of 103 #s and it was tight for me! For what I paid, I feel I was kind of ripped off. I think they should have given me the empty comfort seat for the inconvenience. There was no apology nor any explanation as to why the flight was cancelled. My guess is it benefitted Delta in some way.

Very smooth, on-time, and pleasantly uneventful flight. The team at the gate and on board were professional and genuinely courteous. The pilot kept us well updated throughout, and both takeoff and landing were steady and enjoyable without any drama. Just a good, solid flight. Thank you! 💗

Staff was exceptional! Everyone was kind, professional and friendly making the trip very pleasant. Thank you!

No lunch on a x-country flight scheduled for 10:50 am departure, arrived 5+ hrs later. That requires a black box label before you pay for the tickets. Worst, when I checked in online, it's specifically said that lunch was served on his flight for economy Plus passengers.

We had a lot of really rough weather but that was not Delta's fault. Pilot was amazing.

First, Delta needs more flights to/from Miami. Second, a 1000pm leaving at 1230pm is unacceptable from their biggest airport world hub. Another aircraft could have been used such as the aircraft scheduled to be used in the morning for that exact same route. Yes, I did get me there but the lack of sleep the next day didn't help me enjoy my entire trip since I was busy with activities during the weekend. This can be and is expected from Spirit (going bankrupt) and Frontier (despite they're nickel and dimers). But from Delta's World Hub? That's totally unacceptable!

This flight was straightforward and without difficulty. Service was OK, but I continue to be underwhelmed by level of attention given to Sky Priority passengers.

Good flight, boarding ok and crew very nice. Flight was not full so I was able to be very comfortable. Blanket and pillow provided with was good as it was very cold during the flight . Food was very good(small snack sandwich and an excellent piece of orange cake). Overall good flight, no complaints.

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

Just to drop my already labeled bag it took 50 minutes inline. Completely disappointed with Latam operation at GRU

I’m entitled to a refund per LATAM due to the mid flight itinerary change and being stuck in São Paulo for 24 hours and needing to get a hotel. The airline was dismissive and of no help.

The flight was late. Please do not delay next time.

I couldn't travel, now I can't get a refund and to change the date I have to pay an absurd fine.

Boarding was confusing with a delayed flight because there was no English translation

My biggest complaint is the comfort. I am not tall and there was no legroom. It was very uncomfortable. During my transfer in Sao Paola, the flight was slightly delayed so boarding was confusing because there were no instructions in English.

I never got this flight. You sent me to Chile!!! And from Chile I got the other flight to São Paulo... I've arrived 7h latter than I was supposed to arrive because of Delta delays.

Because the flight was late, we lost the connection to Brazil. You, Delta delayed, and you Delta anticipated the door closing in 15 min from Miami to GRU. Why? It caused a lot of stress! I almost could not see my mother in law alive because of your delay.

I was not able to get on the flight due to delays out of Philadelphia. I arrived in MIA at 10:30pm and there was no one at the GOL Desk. Is there any flight credit available for this flight?

I have a hand injury and the flight attendant denied to help me with luggage, she said "she couldn't help me because I should manage my own way to put the luggage on the plane" SO RUDE

I had two around 6 hours flight and they did not even offer water to us.

Overall it was good. The food was not great quality and seats were very uncomfortable. But overall the staff was very friendly and helpful.

We flew with Avianca, some how they are not n sync, making the process a bit uncomfortable.

Unfortunately it was very disappointed experience. Our first flight our was delayed 2 hours, as a consequence we missed our connecting international flight. Customer server at Miami American Airlines was very disrespectful, gave us the worst replace itenarary for the next day that we had to spend 2 hours calling Gol to get a better itinerary otherwise we wouldn't make it on time to fulfill our trip purpose. We would have missed the reason to travel all the way to Brazil if we didn't change for a better itinerary. The worst thing is that our baggage was missing for 4 days. We had no cloths for all this time, plus the aggravation to locate our baggage. Nobody knew where our baggage was. We ended up picking it up at the airport when they said that they will bring them home. Unfortunately our experience was very dissatisfied.

Flight on time, check in and flight attendants courteous and helpful. Smaller plane for international flights, tight space, no comfortable.

the boarding staff were incredibly officious. our carry-on case was borderline within dimensions but staff were not prepared to show ANY flexibility even though many others with larger carry-on luggage were allowed to board. we were understandably furious but the staff were incredibly disrespectful. we called the supervisor who eventually agreed to look on board the plane to see if there was room for our case (one case between 2 of us) and reluctantly agreed to allow us on. The staff on board were excellent though and realized we had been treated badly and were very helpful both in finding a place for our case, some distance from our seats, and helping us to retrieve it when we landed. We are regular travelers on Gol and have Diamante status and had chosen the better Conforto + seats, so we expected better treatment from the ground staff. Also the cabins are of a size that will only fit 3 cases of normal size with a large gap of about 30cm of wasted space. If our case were deemed to be oversize, which I dispute, the extra 1cm would not have made the slightest difference.

I did not like the way that baggage fees were charged. When I signed up for the flight, I knew that there were bag fees. However, the bag fees were so confusing that it felt like I was paying for overweight bags rather than just for having brought a bag with me. Also, the bag fees were based on the pair of tickets rather than per person. It seems to me that it should be first bag fee for passenger 1 and then first bag fee for passenger 2. I eventually got away with only paying $100 for two bags, but it was a struggle to understand the process. As for the flight, the seats were the standard uncomfortable seats that are on most Boeing aircraft. The airline aims to accommodate the standard height people, so us tall people are stuck. There was never an option to upgrade for leg room. It did not appear that there were any seats on the whole plane that had a little more leg room to even try to get. Other than that, I completely ignored the food for this red eye flight. I am not one to eat "dinner" at 2 am. They did not offer any drinks in the morning before landing. I recommend that you bring a bottle of water on board.

Lost luggage, people are not very nice to help you , I was just instructed to fill out a baggage claim online, they were not helpful when I had additional questions after I completed the form on my phone.

After arriving in Dallas, the aircraft taxied for an unusually long time and was unable to park at the gate, which caused a significant delay and made me miss my connecting flight. I then had to wait in a very long line to be rebooked, and I was told that no hotel or meal accommodations would be provided. What is even more unacceptable is that my luggage was mishandled and has still not been located. My suitcase contains important medications that I urgently need, and I have been unable to access them due to the airline’s mishandling. This situation has caused me considerable stress and inconvenience, and I need this issue to be resolved immediately.

Flight was delayed because of a bird strike. They had another plane available within 45 minutes.

You can plug your phone in & use their wifi to watch movies, etc, but the plane’s wifi was disconnected for most of the flight.

The trip was smooth but the crew were very abrupt, snatching things before finished and being quite snappy when asked questions.

Boarding: Boarding was a bit of a mess. Our tickets indicated "BC" for Business Class, but we and many others were confused as that was not indicated anywhere in the airport, so we didn't know when we're supposed to board. The airplane: The airplane was nice. However, we sat near the back of the business class cabin and the flight attendants and passengers from other cabins would constantly move the curtain (which was very loud), preventing me from fallling asleep on my 8 hour flight. The flight crew: Amazing, generally. However, they nearly forgot to serve breakfast to me. The flight food: I was able to select my meal for dinner, which was really good. Breakfast was a bit of a mess, however. The crew forgot to serve me breakfast until the last minute. Very little was available by the time they remembered. The entertainment: Paltry, underwhelming, and dated. Not one new movie was available. Bottom line: For the money, you might want to consider other options for your international business class flights.

Sat on the ground in Cincinnati for 50 minutes before deplaning

Overall fine, but the delay was annoying and the reasons for the delay were not communicated. The crew on board were phenomenal!

Boarding was very efficient. Everyone got on board and we got on our way very quickly. It was frustrating that the entertainment app was not functioning properly. I was not able to activate some of the movies offered. The crew on this flight appears to be pretty grumpy. They had no smile on their faces. I felt like they were doing us a favor for being there.

Delayed because of weather in Nashville. I think God or some higher power generally has cursed me when it comes to flying out of Charlotte on American. I'm delayed pretty much everytime. We need Team Cobra Kai types to come in and "sweep the leg(s)" of the Charlotte ops people on principle. Don't let the sweet southern rocking chairs fool you, Charlotte is a sinkhole

Long 5 hour and 45 min flight and only one drink service and cookie snack

Cancelled my flight and the earliest that they are willing give me for the next flight which was 3 days later on a weekday. Only accommodation they are willing to give was $30 airline credit that will expire in 1 year

Terrible Airline I will never fly that airline again. Shame on you for recommending them.

Flight was canceled, huge lines to get baggage returned. Most other airlines had delays but not widespread cancellations like Spirit.

never ever fly spirit airlines you will be screwed in the end

I didn't eat, so I can't rate the food. Delayed set off was beyond

No free snacks or drinks. Freezing. Uncomfortable. No plugs or entertainment. If you fly to LA the make you change terminals with a slow bus. Awful trip that took forever. Terrible airline- maybe the worst I’ve ever flown.

I hope you continue to be one of the great company

Crew are always very angry and dismissive like they seem they are being forced to work. In addition, there was a long line for the bathrooms, and only one was allowed to be used. No reason was given for only one bathroom being available; apparently, the stewardess was more interested in using the jumpseat instead of allowing the customers to use the bathroom.

Very positive in both directions. Safe travels, nice staff, lost and found in fact found my phone under my chair! I was out of cash after my NYC trip otherwise I would've offered a reward for helping my day out immensly! Thanks you so much Spirit staff!

I stopped flying spirit as much because they are crooks and thieves. It's not like other airlines where you can at least get credits they just take your money.

Everything you need to know for your flight to South America

Information on your arrival and departure airports