$110 Find Cheap Flights from Charlotte to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Charlotte to South America departing on 12/9. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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1 adult, Economy

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Cheap Flights from Charlotte to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima2 stops$515
Bogotá
Bogotá1 stop$358
Buenos Aires
Buenos Aires3 stops$778
Sao Paulo
Sao Paulo2 stops$602
Rio de Janeiro
Rio de Janeiro2 stops$652
Santiago
Santiago2 stops$635
Cartagena
Cartagena1 stop$317
Quito
Quito2 stops$542
Guayaquil
Guayaquil2 stops$344
Cali
Cali1 stop$376
Cusco
Cusco2 stops$688
Pereira
Pereira2 stops$447
Montevideo
Montevideo1 stop$760
Barranquilla
Barranquilla1 stop$483
Santa Marta
Santa Marta2 stops$473
Lima
Lima2 stops$515
Bogotá
Bogotá1 stop$358
Buenos Aires
Buenos Aires3 stops$778
Sao Paulo
Sao Paulo2 stops$602
Rio de Janeiro
Rio de Janeiro2 stops$652
Santiago
Santiago2 stops$635
Cartagena
Cartagena1 stop$317
Quito
Quito2 stops$542
Guayaquil
Guayaquil2 stops$344
Cali
Cali1 stop$376
Cusco
Cusco2 stops$688
Pereira
Pereira2 stops$447
Montevideo
Montevideo1 stop$760
Barranquilla
Barranquilla1 stop$483
Santa Marta
Santa Marta2 stops$473

Book Cheap Charlotte to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Charlotte to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Charlotte to South America

Fri, Dec 5 - Sun, Dec 7
Spirit Airlines Logo
3:15 pm - 1:20 amCLT-MDE
10h 05m1 stop
Spirit Airlines Logo
2:15 am - 9:39 amMDE-CLT
7h 24m1 stop
$279Spirit Airlines
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Fri, Dec 5 - Thu, Dec 11
Spirit Airlines Logo
3:15 pm - 1:20 amCLT-MDE
10h 05m1 stop
Spirit Airlines Logo
2:15 am - 9:39 amMDE-CLT
7h 24m1 stop
$297Spirit Airlines
Find Deal
Thu, Feb 5 - Thu, Feb 19
American Airlines Logo
5:15 am - 11:22 pmCLT-GYE
18h 07m1 stop
American Airlines Logo
2:33 pm - 9:14 amGYE-CLT
18h 41m1 stop
$503American Airlines
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Wed, Feb 4 - Thu, Feb 19
American Airlines Logo
10:50 am - 11:22 pmCLT-GYE
12h 32m2 stops
American Airlines Logo
2:33 pm - 8:16 amGYE-CLT
17h 43m1 stop
$508American Airlines
Find Deal
Mon, Dec 8 - Wed, Dec 17
Delta Logo
7:18 pm - 1:40 amCLT-GYE
30h 22m2 stops
Delta Logo
4:30 pm - 9:19 amGYE-CLT
16h 49m1 stop
$515Delta
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Mon, Jan 12 - Fri, Jan 23
Delta Logo
4:30 pm - 5:17 amCLT-UIO
12h 47m2 stops
Delta Logo
7:00 pm - 1:10 pmUIO-CLT
18h 10m2 stops
$548Delta
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Sun, Mar 8 - Fri, Mar 13
GOL Logo
7:30 pm - 1:25 pmCLT-GRU
40h 55m2 stops
GOL Logo
5:15 pm - 9:55 pmGRU-CLT
29h 40m2 stops
$602GOL
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Tue, Mar 24 - Sun, Apr 5
LATAM Airlines Logo
11:45 am - 8:35 pmCLT-UIO
9h 50m1 stop
LATAM Airlines Logo
11:30 pm - 8:40 amUIO-CLT
8h 10m1 stop
$609LATAM Airlines
Find Deal
Tue, Mar 24 - Sun, Apr 5
LATAM Airlines Logo
2:20 pm - 5:17 amCLT-UIO
15h 57m2 stops
LATAM Airlines Logo
11:30 pm - 8:40 amUIO-CLT
8h 10m1 stop
$613LATAM Airlines
Find Deal
Tue, Mar 10 - Fri, Mar 13
GOL Logo
4:15 pm - 7:50 amCLT-GRU
38h 35m2 stops
GOL Logo
6:00 am - 9:43 pmGRU-CLT
16h 43m2 stops
$626GOL
Find Deal
Booking Insights

KAYAK's insights & trends for Charlotte to South America flights

Get data-powered insights and trends into flights from Charlotte to South America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Charlotte to South America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Charlotte to South America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Charlotte to South America is March, when tickets cost $718 (return) on average. On the other hand, the most expensive months are December and August, when the average cost of round-trip tickets is $916 and $848 respectively.

What’s the cheapest day of the week to fly from Charlotte to South America?

The average price of all round-trip flights from Charlotte to South America clicked on KAYAK for each day over the last 12 months.

For Charlotte to South America, Tuesday is the cheapest day to fly on average and Friday is the most expensive. Flying from South America back to Charlotte, the best deals are generally found on Tuesday, with Sunday being the most expensive.

How far in advance should I book a flight from Charlotte to South America?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Charlotte to South America, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Charlotte to South America, you should book around 4 weeks before departure, which saves you about 21% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 11 weeks before departure.

Good to know

Low seasonSeptember
Cheapest flight$110
Best time to beat the crowds with an average 18% drop in price.
Most popular time to fly with an average 26% increase in price.
Flight from Charlotte to Medellín

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Charlotte to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Charlotte to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Charlotte to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Charlotte to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Charlotte to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Charlotte to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Charlotte to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Charlotte to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to South America?

    The cheapest time of day to fly to South America is generally at night, when round-trip flights cost $685 on average. Morning departures are around 6% cheaper than evening flights, on average. The most expensive time of day to fly to South America is generally in the evening, which is peak travel time and where the average cost of a ticket is $874.

Reviews of the top 5 airlines serving from Charlotte to South America

 
Need help choosing which airline to fly with from Charlotte to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 7982 reviews
8.5Crew
7.9Entertainment
7.9Comfort
7.3Food
8.2Boarding
Airline reviews

They changed planes and the new plane couldn’t carry enough fuel to fly across the country so we had to stop in Kansas City to refuel. Flight was delayed .

2.0 MediocreLeslie, Oct 2025BOS - SFO
Read more Delta reviews

They changed planes and the new plane couldn’t carry enough fuel to fly across the country so we had to stop in Kansas City to refuel. Flight was delayed .

Flight was too crowded and seats are too small, especially since passengrs are getting larger. Having a middle seat is ALWAYS tough! Woman on my left was large & kept creeping in to my space. Flight personnel were great! Have more savory rather than sweet snacks please.

Flight was crowded and the woman sitting on my left was large & kept crouching in to my space. You need bigger seats or smaller passengers to fit into the seats you DO have! Snack were OK. Would appreciate if airlines had more savory rather than sweet snacks, thank you!

Delayed flight (1hour) plus a long layover after an overnight flight with no backup plane available.

We were delayed, which I think had to do with air traffic control. Otherwise, everything was great.

The boarding process needs to be refined. Sometimes the gate crew calls out the zones and then flip to showing the.zones boarding on the gate monitor display. So, unless you are huddled around the gate lanes watching the monitor, you could miss your boarding zone. Suggest the zones be announced each time a new zone is allowed to board.

The boarding process needs to be refined. Sometimes the gate crew call out the boarding zone, and then flip to the monitor to show which zones are boarding. So unless everyone is gathered around to see the monitor there is usually confusion as wi which zones are boarding.

On time flight. Seat comfort could be better in the Comfort section.

My issue was with TSA agents for delta airlines. My luggage got flagged. The agent was going thru another persons first. He took 20 min to go thru hers. I asked them to bring mine closer so I could sit down . They said you can go sit it will be fine. I said I am supposed to keep my eyes on my bags at all times. The agent was meticulously unwrapping 2 gifts that the lady had and then tried to re warp it. He was trying to be kind i get it but 20 min for me to stand watching him do that was ridiculous. It was 6 am and there were a ton of travelers. Mine was flagged for some air packed tea that I bought in Turkey. My previous delta flight and 2 others before didn’t flag it. Consistency would be nice. Also on the flight the window shades were down for take off and landing - I thought that was very odd I thought they had to remain open for take off and landing.

The flight was an hour and a half late departing which was inconvenient

Just to drop my already labeled bag it took 50 minutes inline. Completely disappointed with Latam operation at GRU

Really bad experience – delayed for 6 hours without any notice, no food or drinks provided, and stuck in the horrible Cartagena airport.

I’m entitled to a refund per LATAM due to the mid flight itinerary change and being stuck in São Paulo for 24 hours and needing to get a hotel. The airline was dismissive and of no help.

The flight was late. Please do not delay next time.

I couldn't travel, now I can't get a refund and to change the date I have to pay an absurd fine.

Boarding was confusing with a delayed flight because there was no English translation

My biggest complaint is the comfort. I am not tall and there was no legroom. It was very uncomfortable. During my transfer in Sao Paola, the flight was slightly delayed so boarding was confusing because there were no instructions in English.

Horrible the worst airlines I have ever flown. Cancelled flight with no choices and when contacted them they were not helpful

I never got this flight. You sent me to Chile!!! And from Chile I got the other flight to São Paulo... I've arrived 7h latter than I was supposed to arrive because of Delta delays.

Because the flight was late, we lost the connection to Brazil. You, Delta delayed, and you Delta anticipated the door closing in 15 min from Miami to GRU. Why? It caused a lot of stress! I almost could not see my mother in law alive because of your delay.

I have a hand injury and the flight attendant denied to help me with luggage, she said "she couldn't help me because I should manage my own way to put the luggage on the plane" SO RUDE

I had two around 6 hours flight and they did not even offer water to us.

Overall it was good. The food was not great quality and seats were very uncomfortable. But overall the staff was very friendly and helpful.

We flew with Avianca, some how they are not n sync, making the process a bit uncomfortable.

Unfortunately it was very disappointed experience. Our first flight our was delayed 2 hours, as a consequence we missed our connecting international flight. Customer server at Miami American Airlines was very disrespectful, gave us the worst replace itenarary for the next day that we had to spend 2 hours calling Gol to get a better itinerary otherwise we wouldn't make it on time to fulfill our trip purpose. We would have missed the reason to travel all the way to Brazil if we didn't change for a better itinerary. The worst thing is that our baggage was missing for 4 days. We had no cloths for all this time, plus the aggravation to locate our baggage. Nobody knew where our baggage was. We ended up picking it up at the airport when they said that they will bring them home. Unfortunately our experience was very dissatisfied.

Flight on time, check in and flight attendants courteous and helpful. Smaller plane for international flights, tight space, no comfortable.

the boarding staff were incredibly officious. our carry-on case was borderline within dimensions but staff were not prepared to show ANY flexibility even though many others with larger carry-on luggage were allowed to board. we were understandably furious but the staff were incredibly disrespectful. we called the supervisor who eventually agreed to look on board the plane to see if there was room for our case (one case between 2 of us) and reluctantly agreed to allow us on. The staff on board were excellent though and realized we had been treated badly and were very helpful both in finding a place for our case, some distance from our seats, and helping us to retrieve it when we landed. We are regular travelers on Gol and have Diamante status and had chosen the better Conforto + seats, so we expected better treatment from the ground staff. Also the cabins are of a size that will only fit 3 cases of normal size with a large gap of about 30cm of wasted space. If our case were deemed to be oversize, which I dispute, the extra 1cm would not have made the slightest difference.

I did not like the way that baggage fees were charged. When I signed up for the flight, I knew that there were bag fees. However, the bag fees were so confusing that it felt like I was paying for overweight bags rather than just for having brought a bag with me. Also, the bag fees were based on the pair of tickets rather than per person. It seems to me that it should be first bag fee for passenger 1 and then first bag fee for passenger 2. I eventually got away with only paying $100 for two bags, but it was a struggle to understand the process. As for the flight, the seats were the standard uncomfortable seats that are on most Boeing aircraft. The airline aims to accommodate the standard height people, so us tall people are stuck. There was never an option to upgrade for leg room. It did not appear that there were any seats on the whole plane that had a little more leg room to even try to get. Other than that, I completely ignored the food for this red eye flight. I am not one to eat "dinner" at 2 am. They did not offer any drinks in the morning before landing. I recommend that you bring a bottle of water on board.

Lost luggage, people are not very nice to help you , I was just instructed to fill out a baggage claim online, they were not helpful when I had additional questions after I completed the form on my phone.

They are not ready for international flights, poor service and food, no screen info on the seat.

Flight was delayed because of a bird strike. They had another plane available within 45 minutes.

You can plug your phone in & use their wifi to watch movies, etc, but the plane’s wifi was disconnected for most of the flight.

The trip was smooth but the crew were very abrupt, snatching things before finished and being quite snappy when asked questions.

Boarding: Boarding was a bit of a mess. Our tickets indicated "BC" for Business Class, but we and many others were confused as that was not indicated anywhere in the airport, so we didn't know when we're supposed to board. The airplane: The airplane was nice. However, we sat near the back of the business class cabin and the flight attendants and passengers from other cabins would constantly move the curtain (which was very loud), preventing me from fallling asleep on my 8 hour flight. The flight crew: Amazing, generally. However, they nearly forgot to serve breakfast to me. The flight food: I was able to select my meal for dinner, which was really good. Breakfast was a bit of a mess, however. The crew forgot to serve me breakfast until the last minute. Very little was available by the time they remembered. The entertainment: Paltry, underwhelming, and dated. Not one new movie was available. Bottom line: For the money, you might want to consider other options for your international business class flights.

Sat on the ground in Cincinnati for 50 minutes before deplaning

Overall fine, but the delay was annoying and the reasons for the delay were not communicated. The crew on board were phenomenal!

Boarding was very efficient. Everyone got on board and we got on our way very quickly. It was frustrating that the entertainment app was not functioning properly. I was not able to activate some of the movies offered. The crew on this flight appears to be pretty grumpy. They had no smile on their faces. I felt like they were doing us a favor for being there.

Delayed because of weather in Nashville. I think God or some higher power generally has cursed me when it comes to flying out of Charlotte on American. I'm delayed pretty much everytime. We need Team Cobra Kai types to come in and "sweep the leg(s)" of the Charlotte ops people on principle. Don't let the sweet southern rocking chairs fool you, Charlotte is a sinkhole

Long 5 hour and 45 min flight and only one drink service and cookie snack

Newark airport grounded inbound flight and only announced when the flight was about to start taxing.

Vegas is such a quick flight that amenities aren’t the important part, in my opinion. Just get me there efficiently and safely, and that’s exactly what they did!

The flight was severely delayed due to the missing flight attendants.

Absolutely horrible. Usually pay $40-$50 to check luggage in. I tried to check my suitcase in and the price is raised to $70. That's ridiculously greedy c'mon. I had to leave my suitcase with all my clothes and hygiene products and repurchase once i landed in Atlanta. You guys make it really stressful to travel. Don't even want to travel anymore.

They cancelled the flight 3 hours prior departure. Had to spend $400 for a ne way flight with Delta Airlines! Spirit Airlines are not serios!

My luggage didn’t arrive at LAX, so that wasn’t a good experience.

Terrible seat, no in flight entertainment. No complimentary food or drinks. Seats really hurt my back after flying spirit for the day.

Plastic seat really hurt my back. Cannot even recline on the flight. Very hard to sleep on the plane due to terrible seats . Food and drinks were expensive and not very good. There were like 2 open exit rows behind me. My isle was full so I asked flight attendants if I could sit there. They told me it was a safety issue??? I think it more unsafe to have no one sitting there. In case of emergency, you’d want someone there to help.

The delays and the lack of communication and organization within the airport itself for Staffing this flight and coordinating the paper log necessary to depart was ridiculous and deplorable

It was a no show, so we got put in hotels for a nite. The A320 plane was very modern and flite and crew (if a pilot shows up were fine). Price was very good.

The entire staff from check in agents to flight attendants were pleasant and professional. Would suggest a complimentary water.

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