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MDE - SCL

$122 Find Cheap Flights from Medellín to Santiago

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Medellín to Santiago departing on 12/8. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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Search hundreds of travel sites at once for deals on flights to Santiago

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Medellín to Santiago, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Medellín to Santiago, as well as popular online travel agencies
In the last 7 days travelers have searched 46,479,581 times on KAYAK, and here is why:

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Cheap Flight Deals from Medellín to Santiago (MDE-SCL)

 
These are the cheapest deals for flights from Medellín to Santiago currently on KAYAK along with options from the most popular airlines KAYAK users selected for this route. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.

Recent round-trip flight deals from Medellín to Santiago

Recommended round-trip deals departing in the coming months from the most popular airlines that fly from Medellín to Santiago.

Recent one-way flight deals from Medellín to Santiago

Only flying one-way? Below are some of the best one-way flight deals from Medellín to Santiago found on KAYAK recently.

Recent last minute flight deals from Medellín to Santiago

Leaving soon but still want a bargain? Check out these latest deals for last minute flights from Medellín to Santiago.

Recent direct flight deals from Medellín to Santiago

The latest deals for direct flights from Medellín to Santiago so you can sit back and relax without the need for a layover.

Cheap bus & train deals from Medellín to Santiago

Find recent round-trip train or bus tickets from Medellín to Santiago.

All round-trip flight deals to Santiago

The cheapest plane tickets to Santiago found on KAYAK recently.
Discover the best prices and deals for you by selecting your travel dates.
Choose your dates
10:00 am - 11:40 pmMDE-SCL
11h 40m2 stops
6:55 am - 2:43 pmSCL-MDE
9h 48m1 stop
$122Avianca
Find Deal
Sun, Dec 8 - Mon, Dec 9
10:00 am - 11:40 pmMDE-SCL
11h 40m2 stops
6:55 am - 4:12 pmSCL-MDE
11h 17m2 stops
$181Avianca
Find Deal
Sun, Dec 8 - Mon, Dec 9
11:30 am - 3:47 amMDE-SCL
14h 17m1 stop
1:32 am - 8:23 amSCL-MDE
8h 51m1 stop
$302Copa Airlines
Find Deal
Mon, Dec 30 - Fri, Feb 28
2:13 pm - 9:21 pmMDE-SCL
6h 08mnonstop
7:49 am - 1:13 pmSCL-MDE
6h 24mnonstop
$328JetSMART
Find Deal
Fri, Apr 11 - Sun, Apr 20
9:21 am - 12:05 amMDE-SCL
12h 44m1 stop
5:24 am - 8:20 pmSCL-MDE
16h 56m1 stop
$335Copa Airlines
Find Deal
Fri, Nov 15 - Sat, Nov 30
6:25 pm - 4:30 amMDE-SCL
8h 05m1 stop
8:10 am - 4:00 pmSCL-MDE
9h 50m1 stop
$338LATAM Airlines
Find Deal
Tue, Nov 12 - Tue, Nov 19
9:07 pm - 5:20 pmMDE-SCL
18h 13m2 stops
6:00 pm - 3:15 amSCL-MDE
11h 15m1 stop
$341LATAM Airlines
Find Deal
Tue, Nov 12 - Tue, Nov 19
1:59 pm - 9:41 amMDE-SCL
18h 42m1 stop
7:49 am - 1:13 pmSCL-MDE
6h 24mnonstop
$350JetSMART
Find Deal
Fri, Apr 11 - Sun, Apr 20
5:50 pm - 1:40 amMDE-SCL
5h 50mnonstop
8:55 pm - 3:30 pmSCL-MDE
20h 35m2 stops
Sun, Dec 8 - Mon, Dec 9
5:59 pm - 5:11 amMDE-SCL
9h 12m1 stop
2:55 pm - 3:00 amSCL-MDE
14h 05m1 stop
Thu, Nov 28 - Thu, Dec 5
6:25 pm - 4:30 amMDE-SCL
8h 05m1 stop
$184LATAM Airlines
Find Deal
Fri, Mar 28
8:47 am - 11:47 pmMDE-SCL
13h 00m1 stop
$186Copa Airlines
Find Deal
Tue, Nov 19
6:29 pm - 5:10 amMDE-SCL
8h 41m1 stop
$189Avianca
Find Deal
Wed, Dec 11
1:13 pm - 9:21 pmMDE-SCL
6h 08mnonstop
$192JetSMART
Find Deal
Fri, Mar 28
6:44 am - 6:17 pmMDE-SCL
9h 33m1 stop
$194JetSMART
Find Deal
Fri, Mar 28
4:15 am - 5:25 pmMDE-SCL
11h 10m1 stop
$217LATAM Airlines
Find Deal
Sat, Nov 16
11:30 am - 11:47 pmMDE-SCL
10h 17m1 stop
$222Copa Airlines
Find Deal
Wed, Nov 6
9:03 pm - 5:25 pmMDE-SCL
18h 22m2 stops
$225LATAM Airlines
Find Deal
Sun, Nov 17
7:22 am - 11:40 pmMDE-SCL
14h 18m2 stops
$235Avianca
Find Deal
Wed, Dec 11
8:19 am - 5:25 pmMDE-SCL
31h 06m3 stops
Sun, Nov 17
9:21 am - 3:38 amMDE-SCL
16h 17m1 stop
3:23 am - 8:20 pmSCL-MDE
18h 57m1 stop
$457Copa Airlines
Find Deal
Sat, Nov 2 - Mon, Nov 11
8:47 am - 3:38 amMDE-SCL
16h 51m1 stop
12:19 pm - 8:20 pmSCL-MDE
10h 01m1 stop
$469Copa Airlines
Find Deal
Sat, Nov 2 - Sun, Nov 10
9:21 am - 3:38 amMDE-SCL
16h 17m1 stop
1:28 am - 10:55 amSCL-MDE
11h 27m1 stop
$493Copa Airlines
Find Deal
Sat, Nov 2 - Tue, Feb 4
3:32 pm - 3:38 amMDE-SCL
10h 06m1 stop
3:23 am - 2:11 pmSCL-MDE
12h 48m1 stop
$764Copa Airlines
Find Deal
Sun, Nov 3 - Thu, Nov 14
11:30 am - 12:05 amMDE-SCL
10h 35m1 stop
3:23 am - 8:20 pmSCL-MDE
18h 57m1 stop
$850Copa Airlines
Find Deal
Sun, Nov 3 - Tue, Nov 12
11:30 am - 3:38 amMDE-SCL
14h 08m1 stop
3:23 am - 5:00 pmSCL-MDE
15h 37m1 stop
$883Copa Airlines
Find Deal
Sun, Nov 3 - Fri, Nov 29
12:15 pm - 3:38 amMDE-SCL
13h 23m1 stop
1:11 am - 8:44 amSCL-MDE
9h 33m1 stop
$975Copa Airlines
Find Deal
Sun, Nov 3 - Sat, Nov 9
2:13 pm - 9:21 pmMDE-SCL
6h 08mnonstop
7:49 am - 1:13 pmSCL-MDE
6h 24mnonstop
$328JetSMART
Find Deal
Fri, Apr 11 - Sun, Apr 20
5:50 pm - 1:40 amMDE-SCL
5h 50mnonstop
3:05 am - 6:55 amSCL-MDE
5h 50mnonstop
$380Avianca
Find Deal
Wed, Dec 11 - Sun, Dec 22
5:50 pm - 1:40 amMDE-SCL
5h 50mnonstop
3:05 am - 6:55 amSCL-MDE
5h 50mnonstop
$407Avianca
Find Deal
Wed, Dec 11 - Sun, Dec 22
1:43 pm - 9:51 pmMDE-SCL
6h 08mnonstop
7:49 am - 12:13 pmSCL-MDE
6h 24mnonstop
$466JetSMART
Find Deal
Wed, Dec 11 - Mon, Dec 23
1:43 pm - 9:51 pmMDE-SCL
6h 08mnonstop
3:05 am - 6:55 amSCL-MDE
5h 50mnonstop
Sun, Dec 8 - Sun, Dec 8
1:43 pm - 9:51 pmMDE-SCL
6h 08mnonstop
7:49 am - 12:13 pmSCL-MDE
6h 24mnonstop
$488JetSMART
Find Deal
Sun, Dec 8 - Mon, Dec 9
1:43 pm - 9:51 pmMDE-SCL
6h 08mnonstop
7:49 am - 12:13 pmSCL-MDE
6h 24mnonstop
$501JetSMART
Find Deal
Wed, Dec 18 - Fri, Dec 27
1:13 pm - 9:21 pmMDE-SCL
6h 08mnonstop
7:49 am - 12:13 pmSCL-MDE
6h 24mnonstop
$514JetSMART
Find Deal
Wed, Jan 1 - Fri, Jan 10
2:38 pm - 10:46 pmMDE-SCL
6h 08mnonstop
7:49 am - 12:13 pmSCL-MDE
6h 24mnonstop
$751JetSMART
Find Deal
Sun, Dec 22 - Wed, Jan 8
5:50 pm - 1:40 amMDE-SCL
5h 50mnonstop
3:05 am - 6:55 amSCL-MDE
5h 50mnonstop
$1,259Avianca
Find Deal
Mon, Mar 3 - Wed, Mar 12

Flights from Medellín to Santiago - Travel Insights & Trends

Get data-powered insights and trends into flights from Medellín to Santiago to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Medellín to Santiago?

The average price of all flights from Medellín Jose Maria Cordova Intl Airport to Santiago clicked on KAYAK for each day over the last 12 months.
For Medellín to Santiago, Tuesday is the cheapest day to fly on average and Saturday is the most expensive. Flying from Santiago back to Medellín, the best deals are generally found on Tuesday, with Friday being the most expensive.

What is the cheapest month to fly from Medellín Jose Maria Cordova Intl Airport to Santiago?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for flights from Medellín Jose Maria Cordova Intl Airport to Santiago, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.
The cheapest month for flights from Medellín Jose Maria Cordova Intl Airport to Santiago is May, where tickets cost $289 on average. On the other hand, the most expensive months are January and February, where the average cost of tickets is $403 and $402 respectively.

How far in advance should I book a flight from Medellín Jose Maria Cordova Intl Airport to Santiago?

To calculate daily average prices, KAYAK takes all prices for each day before departure over the last year for flights from Medellín Jose Maria Cordova Intl Airport to Santiago, removes the top 0.1% to account for outliers, and then takes the average of all the values for each month.
To get a below average price on the flight from Medellín Jose Maria Cordova Intl Airport to Santiago, you should book around 2 days before departure. For the absolute cheapest price, our data suggests you should book 132 days before departure.

Good to know

Low season

February

High season

December

Cheapest flight

$122
Best time to beat the crowds but there is an average 19% increase in price.
Most popular time to fly with an average 9% increase in price.
Flight from Medellín to Santiago

When to book flights from Medellín to Santiago

Are your dates flexible? Find out the best times to travel from Medellín to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking Medellín to Santiago flights

  • What is the cheapest flight from Medellín Jose Maria Cordova Intl Airport to Santiago?

    In the last 3 days, the lowest price for a flight from Medellín Jose Maria Cordova Intl Airport to Santiago was $184 for a one-way ticket and $122 for a round-trip.

  • Do I need a passport to fly between Medellín and Santiago?

    A passport is required to fly from Medellín to Santiago.

  • Which aircraft models fly most regularly from Medellín to Santiago?

    The Airbus A320-100/200 is the aircraft model that flies most regularly on the Medellín to Santiago flight route.

  • Which airline alliances offer flights from Medellín to Santiago?

    Star Alliance is the only airline alliance operating flights between Medellín and Santiago.

  • On which days can I fly direct from Medellín to Santiago?

    You can catch a nonstop flight from Medellín to Santiago on Monday, Wednesday, Friday, Saturday, and Sunday.

  • Which is the best airline for flights from Medellín to Santiago, Copa Airlines or LATAM Airlines?

    The two airlines most popular with KAYAK users for flights from Medellín to Santiago are Copa Airlines and LATAM Airlines. With an average price for the route of $325 and an overall rating of 7.7, Copa Airlines is the most popular choice. LATAM Airlines is also a great choice for the route, with an average price of $327 and an overall rating of 7.5.

  • How does KAYAK find such low prices on flights from Medellín to Santiago?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Medellín to Santiago.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Medellín to Santiago?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santiago from Medellín is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Medellín to Santiago?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santiago with an airline and back to Medellín with another airline. Booking your flights between Medellín and SCL can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Medellín to Santiago?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santiago from Medellín up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

KAYAK’s top tips for finding a cheap flight from Medellín Jose Maria Cordova Intl Airport to Santiago

  • Looking for a cheap flight? 25% of our users found flights on this route for $234 or less one-way.

Prefer to fly non-stop from Medellín to Santiago?

Find which airlines fly direct from Medellín Jose Maria Cordova Intl Airport to Santiago Arturo Merino Benitez Airport, which days they fly and book direct flights.

Nonstop departures

Medellín Jose Maria Cordova Intl to Santiago Arturo Merino Benitez

Monday

Avianca, JetSMART

Avianca, JetSMART

Wednesday

Avianca, JetSMART

Avianca, JetSMART

Friday

Avianca, JetSMART

Avianca, JetSMART

Saturday

JetSMART

JetSMART

Sunday

Avianca, JetSMART

Avianca, JetSMART

See more direct flights

Nonstop returns

Santiago Arturo Merino Benitez to Medellín Jose Maria Cordova Intl

Monday

Avianca, JetSMART

Avianca, JetSMART

Tuesday

Avianca

Avianca

Wednesday

JetSMART

JetSMART

Thursday

Avianca

Avianca

Friday

JetSMART

JetSMART

Saturday

Avianca, JetSMART

Avianca, JetSMART

Sunday

JetSMART

JetSMART

See more direct flights
See more direct flights

Top 4 airlines serving from Medellín to Santiago

 
See real verified KAYAK customer reviews for airlines flying from Medellín to Santiago. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Medellín to Santiago? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.7
Copa AirlinesOverall score based on 1885 reviews
7.9Boarding
7.6Comfort
7.0Entertainment
8.2Crew
7.1Food
Airline reviews

Just a minor inconvinient with weather delay! but not Copa's fault

10.0 ExcellentAdrian, Oct 2024SJO - PTY
Read more Copa Airlines reviews

Just a minor inconvinient with weather delay! but not Copa's fault

Copa delayed the fight three times. We ended up flying about 24 hours after the original time.

The personnel at the counter was very helpful. Everything ran on time.

Very good, despite we had a delay because of some problems at the airport.

Copa me elige como "voluntario" para cambiarme y poder enviar a una familia a la cual había sobrevendido los tiquetes. Finalmente me envían a las carreras con Avianca, pero Copa lleva mis maletas hasta Panama y luego las devuelve a mi aeropuerto de origen, dejandome sin mis pertenencias y además no asumen la responsabilidad ya que dicen que es problema de Avianca Literalmente vi cuando el avión de Copa se lleva mis maletas, sus funcionarios en Bogota, incluyendo la gerente local me aseguran la entrega en Miami, pero simplemente era para poder engañarme y dar el cambio de silla por sobreventa

As usual, the flight with normal legroom was not very comfortable, but the second flight was much better because we had paid for extra legroom. It was very nice to check our bags without an extra fee.

other than a slight delay in takeoff from Panama , the flights were excellent ..... we will continue to use Copa whenever possible for flights to and from Central and South America ....

la atencion en el avion fue excelente, la facilidad del checkin es muy buena.

Cons: "The turbulence was really bad ! I couldn’t sleep at all !"
Pros: "Both of my flights were on time which i know sounds basic but all of the flights i’ve catched from SJO to X were late and this time my connection in Panama was only 1h15 and we got there earlier, so that was nice!"
Cons: "A bunch of seats were free and we were mostly sat all together (3 person next to each other).. With the covid situation i think it could be good to be more separate if possible"

The boading process was fine. Had to wait for bus from tarmac to terminal. Had to go through 2 or 3 security checkpoints in Lima to make next connecting flight.

It was a long and boring flight with no entertainment and no meal only a drink and very bad bag of chips

The crew was amazing. The best in the last times. Great group of people.

Just some cookies and water. There could be other options for food.

On time. At least they offer a drink and a small snack. Plane was clean

You delayed my trip three days for no reason other than your lack of preparedness, did not offer any compensation, including food or a bed. I couldn’t trust you so I moved up my return flight and lost another day at the end of my trip to hopefully make sure I make my next flight. I will never fly LATAM again. You have the worse accountability and reliability and clearly do not care that your clients have lives and what it cost to fly to another country.

Airline lost my luggage and after 20 days it has not been returned nor refunded any money.

I do not read or speak in Spanish. Only English. When asking for help, the people spoke quickly in English and pointed a lot. I wish they would’ve spoken a little slower for me to understand. There was much confusion and hurried in their message and I was unclear as to where to go

I didn't realize they didn't have bathrooms on the plane. Almost had a very bad situation.

It was confusing because I got a notification that my gate was changed when in reality it wasn’t

COP 7,000 for a cup of mediocre coffee. I thought I was on Spirit Airlines for a minute. Otherwise the flight was fine. Nothing exceptional to report.

Overpriced checked bag price of $120 and they charge you for carryon if the size is not minimal of $120.

Be very careful of the initial low price because Avianca wil bill you for a carryon of $120 or a checked bag for $120. Also, be careful with connections because the customs entry process is slow and the connecting terminal is not close.

My whole return flight itinerary, 3 flights, got canceled without any warning to me because I missed one of the earlier flights 3 weeks ago

The connection time is too short to pass through customs and once you do clear customs the connecting flight is in another terminal that is not close.

Boarding, crew and food. Seats are too small Love Avianca

Worst airline , charge for everything even for water, seat space is very bad

Horrible. I have been trying to speak to a representative to know why I was over charged but I get redirected to AI Vianca everytime with no results. Is there an agency that oversees airline gouging? I will never fly or recommend Avianca to anyone not that you care.

Felt very cramped in the back of plane. There was an hour delay for take off sitting on the runway, but we did arrive on time. They charge $120 for carry on bag and backpack at the airport its ridiculous.

Almost we lost our connection from Bogota to Aruba 🥴 Because we get out late from the plane of Medellin

There was no entertainment but everyone just used their phones.

The app told us that carry on luggage was included but we were made to pay for it again at the check in counter, making it a very expensive flight. Not happy

I was charged 168 soles for kids stroller. We have travelled across the world and have never charged for the stroller. Horrific airlines and the staff was extremely rude. They wouldn’t let us board unless we pay the extra baggage cost. Never ever flying this airline and I would recommend the same for the others.

Avoid this airline. They are unprofessional. The captain left several passengers on ground due to covid restrictions which were never communicated. As a chilean, I am ashamed that this low level airline comes from my country. Remember this horrible brand and avoid it... Jetsmart

Cons: "The plane was cramped. It was difficult to fit even small, personal items under the seat, especially if you want to put your feet there, too."
Pros: "They rescheduled the flight to 12 hours prior and I wasn’t notified and showed up at airport and didn’t have a flight got stuck kiwi said they wouldn’t help me were so mean had to buy new flight wasting thousands of dollars"
Cons: "Everything"
Cons: "Several safety issues onboard: luggage put in unsafe places, seatbelt sign missing during landing, restroom doors flapping open during flight. No free water. No towels or toilet paper."
Pros: "Worst experience and kayak take responsibility. Plane delayed 7 hours without message and with confusing timing. Was still showing plane flight 331 still at 3pm but delayed till 10pm. Showing. Arrival to still be 6pm. Then delayed again without any indication. Huge problem I lost a lot"
Cons: "Let us know when there is delay and be responsible"

Book cheap flights from Medellín to Santiago

Recent one-way flight deals

 
Only flying one-way? Below are some of the best one-way flight deals from Medellín to Santiago found on KAYAK in the last 72 hours.
3/28Fri
1 stopLATAM Airlines
8h 05mMDE-SCL
$184
11/19Tue
1 stopCopa Airlines
13h 00mMDE-SCL
$186
12/11Wed
1 stopAvianca
8h 41mMDE-SCL
$189
3/28Fri
nonstopJetSMART
6h 08mMDE-SCL
$192
3/28Fri
1 stopJetSMART
9h 33mMDE-SCL
$194
11/16Sat
1 stopLATAM Airlines
11h 10mMDE-SCL
$217
11/6Wed
1 stopCopa Airlines
10h 17mMDE-SCL
$222
11/17Sun
2 stopsLATAM Airlines
18h 22mMDE-SCL
$225
12/11Wed
2 stopsAvianca
14h 18mMDE-SCL
$235
11/17Sun
3 stops
31h 06mMDE-SCL
$286

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Last minute flights from Medellín to Santiago

Last minute flight, train and bus deals

 
These last-minute flight deals are the cheapest flights found on KAYAK in the last 72 hours for flights from Medellín to Santiago that are departing in the next 10 days.
11/2Sat
multi-stopCopa Airlines
16h 17mMDE-SCL
11/11Mon
multi-stopCopa Airlines
18h 57mSCL-MDE
$457
11/2Sat
multi-stopCopa Airlines
16h 51mMDE-SCL
11/10Sun
multi-stopCopa Airlines
10h 01mSCL-MDE
$469
11/2Sat
multi-stopCopa Airlines
16h 17mMDE-SCL
2/4Tue
multi-stopCopa Airlines
11h 27mSCL-MDE
$493
11/3Sun
multi-stopCopa Airlines
10h 06mMDE-SCL
11/14Thu
multi-stopCopa Airlines
12h 48mSCL-MDE
$764
11/3Sun
multi-stopCopa Airlines
10h 35mMDE-SCL
11/12Tue
multi-stopCopa Airlines
18h 57mSCL-MDE
$850
11/3Sun
multi-stopCopa Airlines
14h 08mMDE-SCL
11/29Fri
multi-stopCopa Airlines
15h 37mSCL-MDE
$883
11/3Sun
multi-stopCopa Airlines
13h 23mMDE-SCL
11/9Sat
multi-stopCopa Airlines
9h 33mSCL-MDE
$975

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Everything you need to know for your flight from Medellín to Santiago

Information on your arrival and departure airports